Dietary supplement use in the older population of Iceland and association with mortality.
Dietary supplements are often used by the elderly to improve their nutritional status. However, intake above the recommended dietary levels may be detrimental, and uncertainty exists on the potential health benefits of supplementation in this population. The aim of this study was to describe supplem...
Published in: | British Journal of Nutrition |
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Format: | Article in Journal/Newspaper |
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Cambridge University Press
2017
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Online Access: | http://hdl.handle.net/2336/620278 https://doi.org/10.1017/S0007114517001313 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620278 2023-05-15T16:47:31+02:00 Dietary supplement use in the older population of Iceland and association with mortality. Ólafsdóttir, Birta Gunnarsdóttir, Ingibjörg Nikulásdóttir, Hjálmfríður Eiríksdóttir, Guðný Harris, Tamara B Launer, Lenore J Guðnason, Vilmundur Halldórsson, Thórhallur I Einarsdóttir, Kristjana 1 Univ Iceland, Sch Hlth Sci, Unit Nutr Res, Eiriksgata 29, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 2 Landspitali Univ Hosp, Eiriksgata 29, IS-101 Reykjavik, Iceland 3 Iceland Heart Assoc, Holtasmari 1, IS-201 Kopavogur, Iceland Show the Organization-Enhanced name(s) 4 NIA, 31 Ctr Dr,MSC 2292, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 5 Univ Iceland, Saemundargata 2, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 6 Univ Iceland, Ctr Publ Hlth Sci, Sch Hlth Sci, Sturlugata 8, IS-101 Reykjavik, Iceland 2017-05 http://hdl.handle.net/2336/620278 https://doi.org/10.1017/S0007114517001313 en eng Cambridge University Press https://www.cambridge.org/core/services/aop-cambridge-core/content/view/CC7EE49AAB7A9274E24D0A563EDADDDB/S0007114517001313a.pdf/dietary_supplement_use_in_the_older_population_of_iceland_and_association_with_mortality.pdf Dietary supplement use in the older population of Iceland and association with mortality. 2017, 117 (10):1463-1469 Br. J. Nutr. 1475-2662 28606218 doi:10.1017/S0007114517001313 http://hdl.handle.net/2336/620278 The British journal of nutrition Archived with thanks to The British journal of nutrition Landspitali Access - LSH-aðgangur Aldraðir Vítamín Lífslíkur NUR12 Aged 80 and over Dietary Supplements Female Humans Iceland Male Nutrition Surveys Nutritional Requirements Vitamins Article 2017 ftlandspitaliuni https://doi.org/10.1017/S0007114517001313 2022-05-29T08:22:16Z Dietary supplements are often used by the elderly to improve their nutritional status. However, intake above the recommended dietary levels may be detrimental, and uncertainty exists on the potential health benefits of supplementation in this population. The aim of this study was to describe supplement use among Icelandic older adults and to assess its association with total mortality and CVD-related mortality. This study used data from the Age Gene/Environment Susceptibility-Reykjavik study, which recruited 5764 participants aged 66-98 years in 2002-2006. Intake of vitamins and minerals from dietary supplements was estimated from interviews. Hazard ratios (HR) for mortality were estimated in multivariate analyses with follow-up ending in 2009. The results showed that most (77 %) of the participants used supplements. Overall, the consumption of vitamins and minerals from supplements was moderate although 22 and 14 % of users exceeded the upper recommended intake levels for vitamin B6 and Zn, respectively. Supplement users followed in general a healthier lifestyle than non-users. There were 1221 deaths including 525 CVD-related deaths during the follow-up period. When comparing multivitamin users with non-users in multivariable models, no associations with total mortality (HR 0·91; 95 % CI: 0·77, 1·08) or CVD-related mortality (HR 0·91; 95 % CI 0·70, 1·18) were observed. In conclusion, users of supplements generally lead healthier lifestyles than non-users and supplements did not confer any added advantage or harm relative to mortality risk. However, the intake of vitamin B6 and Zn from dietary supplements exceeded the recommended daily intake for almost a quarter of the supplement users. University of Iceland Research Fund Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive British Journal of Nutrition 117 10 1463 1469 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Aldraðir Vítamín Lífslíkur NUR12 Aged 80 and over Dietary Supplements Female Humans Iceland Male Nutrition Surveys Nutritional Requirements Vitamins |
spellingShingle |
Aldraðir Vítamín Lífslíkur NUR12 Aged 80 and over Dietary Supplements Female Humans Iceland Male Nutrition Surveys Nutritional Requirements Vitamins Ólafsdóttir, Birta Gunnarsdóttir, Ingibjörg Nikulásdóttir, Hjálmfríður Eiríksdóttir, Guðný Harris, Tamara B Launer, Lenore J Guðnason, Vilmundur Halldórsson, Thórhallur I Einarsdóttir, Kristjana Dietary supplement use in the older population of Iceland and association with mortality. |
topic_facet |
Aldraðir Vítamín Lífslíkur NUR12 Aged 80 and over Dietary Supplements Female Humans Iceland Male Nutrition Surveys Nutritional Requirements Vitamins |
description |
Dietary supplements are often used by the elderly to improve their nutritional status. However, intake above the recommended dietary levels may be detrimental, and uncertainty exists on the potential health benefits of supplementation in this population. The aim of this study was to describe supplement use among Icelandic older adults and to assess its association with total mortality and CVD-related mortality. This study used data from the Age Gene/Environment Susceptibility-Reykjavik study, which recruited 5764 participants aged 66-98 years in 2002-2006. Intake of vitamins and minerals from dietary supplements was estimated from interviews. Hazard ratios (HR) for mortality were estimated in multivariate analyses with follow-up ending in 2009. The results showed that most (77 %) of the participants used supplements. Overall, the consumption of vitamins and minerals from supplements was moderate although 22 and 14 % of users exceeded the upper recommended intake levels for vitamin B6 and Zn, respectively. Supplement users followed in general a healthier lifestyle than non-users. There were 1221 deaths including 525 CVD-related deaths during the follow-up period. When comparing multivitamin users with non-users in multivariable models, no associations with total mortality (HR 0·91; 95 % CI: 0·77, 1·08) or CVD-related mortality (HR 0·91; 95 % CI 0·70, 1·18) were observed. In conclusion, users of supplements generally lead healthier lifestyles than non-users and supplements did not confer any added advantage or harm relative to mortality risk. However, the intake of vitamin B6 and Zn from dietary supplements exceeded the recommended daily intake for almost a quarter of the supplement users. University of Iceland Research Fund |
author2 |
1 Univ Iceland, Sch Hlth Sci, Unit Nutr Res, Eiriksgata 29, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 2 Landspitali Univ Hosp, Eiriksgata 29, IS-101 Reykjavik, Iceland 3 Iceland Heart Assoc, Holtasmari 1, IS-201 Kopavogur, Iceland Show the Organization-Enhanced name(s) 4 NIA, 31 Ctr Dr,MSC 2292, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 5 Univ Iceland, Saemundargata 2, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 6 Univ Iceland, Ctr Publ Hlth Sci, Sch Hlth Sci, Sturlugata 8, IS-101 Reykjavik, Iceland |
format |
Article in Journal/Newspaper |
author |
Ólafsdóttir, Birta Gunnarsdóttir, Ingibjörg Nikulásdóttir, Hjálmfríður Eiríksdóttir, Guðný Harris, Tamara B Launer, Lenore J Guðnason, Vilmundur Halldórsson, Thórhallur I Einarsdóttir, Kristjana |
author_facet |
Ólafsdóttir, Birta Gunnarsdóttir, Ingibjörg Nikulásdóttir, Hjálmfríður Eiríksdóttir, Guðný Harris, Tamara B Launer, Lenore J Guðnason, Vilmundur Halldórsson, Thórhallur I Einarsdóttir, Kristjana |
author_sort |
Ólafsdóttir, Birta |
title |
Dietary supplement use in the older population of Iceland and association with mortality. |
title_short |
Dietary supplement use in the older population of Iceland and association with mortality. |
title_full |
Dietary supplement use in the older population of Iceland and association with mortality. |
title_fullStr |
Dietary supplement use in the older population of Iceland and association with mortality. |
title_full_unstemmed |
Dietary supplement use in the older population of Iceland and association with mortality. |
title_sort |
dietary supplement use in the older population of iceland and association with mortality. |
publisher |
Cambridge University Press |
publishDate |
2017 |
url |
http://hdl.handle.net/2336/620278 https://doi.org/10.1017/S0007114517001313 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/CC7EE49AAB7A9274E24D0A563EDADDDB/S0007114517001313a.pdf/dietary_supplement_use_in_the_older_population_of_iceland_and_association_with_mortality.pdf Dietary supplement use in the older population of Iceland and association with mortality. 2017, 117 (10):1463-1469 Br. J. Nutr. 1475-2662 28606218 doi:10.1017/S0007114517001313 http://hdl.handle.net/2336/620278 The British journal of nutrition |
op_rights |
Archived with thanks to The British journal of nutrition Landspitali Access - LSH-aðgangur |
op_doi |
https://doi.org/10.1017/S0007114517001313 |
container_title |
British Journal of Nutrition |
container_volume |
117 |
container_issue |
10 |
container_start_page |
1463 |
op_container_end_page |
1469 |
_version_ |
1766037602211725312 |