A randomized controlled trial reporting functional outcomes of cognitive-behavioural therapy in medication-treated adults with ADHD and comorbid psychopathology.

• Published in: European Archives of Psychiatry and Clinical Neuroscience
• Main Authors: Young, Susan, Emilsson, Brynjar, Sigurdsson, Jon Fridrik, Khondoker, Mizanur, Philipp-Wiegmann, Florence, Baldursson, Gisli, Olafsdottir, Halldora, Gudjonsson, Gisli
• Other Authors: 1 Centre for Psychiatry, Imperial College London, Du Cane Road, London, W12 0NN, UK. [e-mail]. 2 Broadmoor Hospital, WLMHT, Crowthorne, UK. [e-mail]. 3 Reykjavik University, Reykjavik, Iceland. [e-mail]. 4 Institute of Psychiatry Psychology and Neuroscience, King's College London, London, UK. 5 Landspitali -The National University Hospital of Iceland, Reykjavik, Iceland. 6 Reykjavik University, Reykjavik, Iceland. 7 University of Iceland, Reykjavik, Iceland. 8 Department of Applied Health Research, University College London, London, UK. 9 Broadmoor Hospital, WLMHT, Crowthorne, UK.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Heidelberg 2017
• Subjects: ADHD; Atferlismeðferð; PSY12; PSC12; Adolescent; Adult; Aged; Antisocial Personality Disorder; Attention Deficit Disorder with Hyperactivity; Cognitive Therapy; Female; Follow-Up Studies; Humans; Linear Models; Male; Middle Aged; Psychiatric Status Rating Scales; Treatment Outcome; Young Adult; Smella; Iceland
• Online Access: http://hdl.handle.net/2336/620177; https://doi.org/10.1007/s00406-016-0735-0

Efst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Studies assessing psychological treatment of attention deficit hyperactivity disorder (ADHD) in adults are increasingly reported. However, functional outcomes are often neglected in favour of symptom outcomes. We investigated functional outcomes in 95 adults with ADHD who were already treated with medication and randomized to receive treatment as usual (TAU/MED) or psychological treatment (CBT/MED) using a cognitive-behavioural programme, R&R2ADHD, which employs both group and individual modalities. RATE-S functional outcomes associated with ADHD symptoms, social functioning, emotional control and antisocial behaviour were given at baseline, end of treatment and three-month follow-up. The Total composite score of these scales is associated with life satisfaction. In addition, independent evaluator ratings of clinicians who were blind to treatment arm were obtained on the Clinical Global Impression scale at each time point. CBT/MED showed overall (combined outcome at end of treatment and 3-month follow-up) significantly greater functional improvement on all scales. Post-group treatment effects were maintained at follow-up with the exception of emotional control and the Total composite scales, which continued to improve. The largest treatment effect was for the RATE-S Total composite scale, associated with life satisfaction. CGI significantly correlated with all outcomes except for social functioning scale at follow-up. The study provides further evidence for the effectiveness of R&R2ADHD and demonstrates the importance of measuring functional outcomes. The key mechanism associated with improved functional outcomes is likely to be behavioural control. Janssen Eli Lilly Shire Novartis and Flynn Pharma RANNIS the Icelandic Centre for Research Landspitali Science Fund Janssen-Cilag, Iceland National Institute for Health Research (NIHR) [Mental Health Biomedical Research Centre] at South London Maudsley NHS Foundation ...