Severe vitamin D deficiency is common in critically ill patients at a high northern latitude.

• Published in: Acta Anaesthesiologica Scandinavica
• Main Authors: Kvaran, R B, Sigurdsson, M I, Skarphedinsdottir, S J, Sigurdsson, G H
• Other Authors: 1 Landspitali Univ Hosp, Dept Anaesthesia & Intens Care Med, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 2 Univ Iceland, Fac Med, Reykjavik, Iceland 3 Brigham & Womens Hosp, Dept Anaesthesia Perioperat & Pain Med, 75 Francis St, Boston, MA 02115 USA
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wiley-Blackwell 2016
• Subjects: D vítamín; Sjúklingar; Gjörgæsla; AAA12; Critical Illness; Vitamin D Deficiency; Scandinavian and Nordic Countries; Iceland; Length of Stay; Prevalence
• Online Access: http://hdl.handle.net/2336/620045; https://doi.org/10.1111/aas.12748

To access publisher's full text version of this article click on the hyperlink at the bottom of the page Critically ill patients at southern latitudes have been shown to have low vitamin D levels that were associated with prolonged hospital stay. To our knowledge no studies have been conducted on vitamin D status amongst critically ill patients at high northern latitudes. Despite the Icelandic population traditionally taking vitamin D supplements, we hypothesized that the majority of critically ill patients in Reykjavik, Iceland have low vitamin D levels. This was a prospective observational study on 122 patients admitted to Landspitali University Hospital intensive care unit. Serum vitamin D (25(OH)D) was measured in all patients on two occasions (first and second day). The prevalence of vitamin D deficiency and its effect on hospital stay was calculated. Only 9% of patients had vitamin D levels recommended for good health (>75 nmol/l) and 69% were deficient (25(OH)D < 50 nmol/l). The average difference between the first and second vitamin D samples was 2.8 nmol/l. Forty-three percentage of the severely vitamin D deficient stayed in the ICU for more than 4 days compared to 19% of patients with better status (P = 0.196). Vitamin D deficiency is very common in critically ill patients at high northern latitudes and patients with severely deficient vitamin D levels had trend towards longer intensive care unit stay. Furthermore, 43% of the patients had vitamin D levels under 25 nmol/l that is associated with osteomalacia. It appears that a single vitamin D measurement gives a reasonable clue about the vitamin D status in critically ill patients. Landspitali University Hospital Research Fund University of Iceland Research Fund, Reykjavik, Iceland