The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis.
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. To investigate the ability of Magnetic resonance cholangiopancreatography (MRCP) to exclud...
Published in: | Scandinavian Journal of Gastroenterology |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Taylor & Francis
2016
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Online Access: | http://hdl.handle.net/2336/620043 https://doi.org/10.1080/00365521.2016.1182584 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/620043 2023-05-15T16:51:49+02:00 The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. Hjartarson, Jón H Hannesson, Pétur Sverrisson, Ingvar Blöndal, Sigurður Ívarsson, Bjarki Björnsson, Einar S 1 Natl Univ Hosp Iceland, Dept Gastroenterol & Hepatol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 2 Natl Univ Hosp Iceland, Dept Radiol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 3 Natl Univ Hosp Iceland, Dept Surg, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 4 Vastmanlands Hosp, Dept Surg, Vasteras 72189, Sweden 5 Hosp Heden Horsens, Billeddiagnost Afdeling, Sundvej 30, DK-8700 Horsens, Denmark 2016 http://hdl.handle.net/2336/620043 https://doi.org/10.1080/00365521.2016.1182584 en eng Taylor & Francis http://dx.doi.org/ 10.1080/00365521.2016.1182584 The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. 2016, 51 (10):1249-56 Scand. J. Gastroenterol. 1502-7708 27181286 doi:10.1080/00365521.2016.1182584 GAS12 DAI12 SAG12 http://hdl.handle.net/2336/620043 Scandinavian journal of gastroenterology Archived with thanks to Scandinavian journal of gastroenterology Open Access GAS12 SAG12 DAI12 SAM12 Cholangiopancreatography Magnetic Resonance Choledocholithiasis Endoscopic Retrograde Common Bile Duct Logistic Models Article 2016 ftlandspitaliuni https://doi.org/10.1080/00365521.2016.1182584 2022-05-29T08:22:12Z To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. To investigate the ability of Magnetic resonance cholangiopancreatography (MRCP) to exclude choledocholithiasis (CDL) in symptomatic patients. Patients suspected of choledocholithiasis who underwent MRCP from 2008 through 2013 in a population based study at the National University Hospital of Iceland were retrospectively analysed, using ERCP and/or intraoperative cholangiography as a gold standard diagnosis for CDL. Overall 920 patients [66% women, mean age 55 years (SD 21)] underwent MRCP. A total of 392 patients had a normal MRCP of which 71 underwent an ERCP investigation demonstrating a CBD stone in 29 patients. A normal MRCP was found to have a 93% negative predictive value (NPV) and 89% probability of having no CBD stone demonstrated as well as no readmission due to gallstone disease within six months following MRCP. During a 6-month follow-up period of the 321 patients who did not undergo an ERCP nine (2.8%) patients were readmitted with right upper quadrant pain and elevated liver tests which later normalised with no CBD stone being demonstrated, three (0.9%) patients were readmitted with presumed gallstone pancreatitis, two (0.6%) patients were readmitted with cholecystitis and two (0.6%) patients were lost to follow-up. Seven patients of those 321 underwent an intraoperative cholangiography (IOC) and all were negative for CBD stones. For the sub-group requiring ERCP following a normal MRCP the NPV was 63%. Our results support the use of MRCP as a tool for exclusion of choledocholithiasis with the potential to reduce the amount of unnecessary ERCP procedures. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Scandinavian Journal of Gastroenterology 51 10 1249 1256 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
GAS12 SAG12 DAI12 SAM12 Cholangiopancreatography Magnetic Resonance Choledocholithiasis Endoscopic Retrograde Common Bile Duct Logistic Models |
spellingShingle |
GAS12 SAG12 DAI12 SAM12 Cholangiopancreatography Magnetic Resonance Choledocholithiasis Endoscopic Retrograde Common Bile Duct Logistic Models Hjartarson, Jón H Hannesson, Pétur Sverrisson, Ingvar Blöndal, Sigurður Ívarsson, Bjarki Björnsson, Einar S The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
topic_facet |
GAS12 SAG12 DAI12 SAM12 Cholangiopancreatography Magnetic Resonance Choledocholithiasis Endoscopic Retrograde Common Bile Duct Logistic Models |
description |
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. To investigate the ability of Magnetic resonance cholangiopancreatography (MRCP) to exclude choledocholithiasis (CDL) in symptomatic patients. Patients suspected of choledocholithiasis who underwent MRCP from 2008 through 2013 in a population based study at the National University Hospital of Iceland were retrospectively analysed, using ERCP and/or intraoperative cholangiography as a gold standard diagnosis for CDL. Overall 920 patients [66% women, mean age 55 years (SD 21)] underwent MRCP. A total of 392 patients had a normal MRCP of which 71 underwent an ERCP investigation demonstrating a CBD stone in 29 patients. A normal MRCP was found to have a 93% negative predictive value (NPV) and 89% probability of having no CBD stone demonstrated as well as no readmission due to gallstone disease within six months following MRCP. During a 6-month follow-up period of the 321 patients who did not undergo an ERCP nine (2.8%) patients were readmitted with right upper quadrant pain and elevated liver tests which later normalised with no CBD stone being demonstrated, three (0.9%) patients were readmitted with presumed gallstone pancreatitis, two (0.6%) patients were readmitted with cholecystitis and two (0.6%) patients were lost to follow-up. Seven patients of those 321 underwent an intraoperative cholangiography (IOC) and all were negative for CBD stones. For the sub-group requiring ERCP following a normal MRCP the NPV was 63%. Our results support the use of MRCP as a tool for exclusion of choledocholithiasis with the potential to reduce the amount of unnecessary ERCP procedures. |
author2 |
1 Natl Univ Hosp Iceland, Dept Gastroenterol & Hepatol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 2 Natl Univ Hosp Iceland, Dept Radiol, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 3 Natl Univ Hosp Iceland, Dept Surg, Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 4 Vastmanlands Hosp, Dept Surg, Vasteras 72189, Sweden 5 Hosp Heden Horsens, Billeddiagnost Afdeling, Sundvej 30, DK-8700 Horsens, Denmark |
format |
Article in Journal/Newspaper |
author |
Hjartarson, Jón H Hannesson, Pétur Sverrisson, Ingvar Blöndal, Sigurður Ívarsson, Bjarki Björnsson, Einar S |
author_facet |
Hjartarson, Jón H Hannesson, Pétur Sverrisson, Ingvar Blöndal, Sigurður Ívarsson, Bjarki Björnsson, Einar S |
author_sort |
Hjartarson, Jón H |
title |
The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
title_short |
The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
title_full |
The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
title_fullStr |
The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
title_full_unstemmed |
The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
title_sort |
value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. |
publisher |
Taylor & Francis |
publishDate |
2016 |
url |
http://hdl.handle.net/2336/620043 https://doi.org/10.1080/00365521.2016.1182584 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/ 10.1080/00365521.2016.1182584 The value of magnetic resonance cholangiopancreatography for the exclusion of choledocholithiasis. 2016, 51 (10):1249-56 Scand. J. Gastroenterol. 1502-7708 27181286 doi:10.1080/00365521.2016.1182584 GAS12 DAI12 SAG12 http://hdl.handle.net/2336/620043 Scandinavian journal of gastroenterology |
op_rights |
Archived with thanks to Scandinavian journal of gastroenterology Open Access |
op_doi |
https://doi.org/10.1080/00365521.2016.1182584 |
container_title |
Scandinavian Journal of Gastroenterology |
container_volume |
51 |
container_issue |
10 |
container_start_page |
1249 |
op_container_end_page |
1256 |
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1766041932858916864 |