Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.

To access publisher's full text version of this article click on the hyperlink at the bottom of the page Several sequence variants are known to have effects on serum levels of non-high-density lipoprotein (HDL) cholesterol that alter the risk of coronary artery disease. We sequenced the genomes...

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Published in:New England Journal of Medicine
Main Authors: Nioi, Paul, Sigurdsson, Asgeir, Thorleifsson, Gudmar, Helgason, Hannes, Agustsdottir, Arna B, Norddahl, Gudmundur L, Helgadottir, Anna, Magnusdottir, Audur, Jonasdottir, Aslaug, Gretarsdottir, Solveig, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Swinkels, Dorine W, Galesloot, Tessel E, Grarup, Niels, Jørgensen, Torben, Vestergaard, Henrik, Hansen, Torben, Lauritzen, Torsten, Linneberg, Allan, Friedrich, Nele, Krarup, Nikolaj T, Fenger, Mogens, Abildgaard, Ulrik, Hansen, Peter R, Galløe, Anders M, Braund, Peter S, Nelson, Christopher P, Hall, Alistair S, Williams, Michael J A, van Rij, Andre M, Jones, Gregory T, Patel, Riyaz S, Levey, Allan I, Hayek, Salim, Shah, Svati H, Reilly, Muredach, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Kiemeney, Lambertus A, Quyyumi, Arshed A, Rader, Daniel J, Kraus, William E, Samani, Nilesh J, Pedersen, Oluf, Thorgeirsson, Gudmundur, Masson, Gisli, Holm, Hilma
Other Authors: eCODE Genetics-Amgen, Faculty of Medicine School of Engineering and Natural Sciences , University of Iceland, the Laboratory in Mjodd Department of Clinical Biochemistry, Division of Cardiology, Department of Internal Medicine , Landspitali, National University Hospital of Iceland, Reykjavik, Department of Clinical Biochemistry, Akureyri Hospital, Akureyri, Iceland, Radboud Institute for Molecular Life Sciences, Department of Laboratory Medicine , Radboud Institute for Health Sciences, Department of Health Evidence , Radboud University Medical Center Nijmegen, Nijmegen, the Netherlands; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics , Institute of Public Health, Faculty of Health and Medical Science, University of Copenhagen, and Research Center for Prevention and Health, Capital Region of Denmark, Copenhagen, Faculty of Medicine, University of Aalborg, Aalborg , Faculty of Health Sciences, University of Southern Denmark, Odense , Department of Public Health, Section of General Practice, University of Aarhus, Aarhus , Department of Clinical Experimental Research, Rigshospitalet, Glostrup , Department of Clinical Biochemistry, University Hospital of Copenhagen at Hvidovre, Hvidovre , Department of Cardiology, Gentofte University Hospital, Hellerup, Department of Cardiology, Roskilde Hospital, Roskilde Denmark;
Format: Article in Journal/Newspaper
Language:English
Published: Massachusetts Medical Society 2016
Subjects:
DNA
Online Access:http://hdl.handle.net/2336/619041
https://doi.org/10.1056/NEJMoa1508419