The Prevalence of Depression among Untreated Obstructive Sleep Apnea Patients Using a Standardized Psychiatric Interview.

• Published in: Journal of Clinical Sleep Medicine
• Main Authors: Björnsdóttir, Erla, Benediktsdóttir, Bryndís, Pack, Allan I, Arnardottir, Erna Sif, Kuna, Samuel T, Gíslason, Thorarinn, Keenan, Brendan T, Maislin, Greg, Sigurdsson, Jón Fridrik
• Other Authors: 1 Univ Iceland, Fac Med, Reykjavik, Iceland 2 Landspitali, Dept Resp Med & Sleep, Reykjavik, Iceland 3 Univ Penn, Sch Med, Ctr Sleep & Circadian Neurobiol, Philadelphia, PA 19104 USA 4 Univ Penn, Sch Med, Dept Med, Div Sleep Med, Philadelphia, PA 19104 USA 5 Landspitali, Mental Hlth Serv, Reykjavik, Iceland 6 Reykjavik Univ, Reykjavik, Iceland 7 Michael J Crescenz Vet Affairs Med Ctr, Philadelphia, PA USA
• Format: Article in Journal/Newspaper
• Language: English
• Published: Amer Acad Sleep Medicine 2016
• Subjects: Þunglyndi; Kæfisvefn; PAD12; NAF12; PSC12; Depression; Sleep Apnea; Obstructive; Psychiatric Status Rating Scales; Iceland
• Online Access: http://hdl.handle.net/2336/618536; https://doi.org/10.5664/jcsm.5406

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. The aims of this study were: (1) to use a standardized psychiatric interview, conducted by a trained psychologist to assess the prevalence of depression among patients with untreated OSA, and (2) to identify if OSA severity or other comorbid disorders (insomnia, hypertension, and diabetes) are related to depression among patients with untreated OSA. Participants were newly diagnosed patients with OSA (n = 284) waiting to start positive airway pressure (PAP) treatment. The Mini International Neuropsychiatric Interview (MINI) was used to assess depression. Overall, 15.5% of the sample met the diagnosis for dysthymia. Women had a significantly higher prevalence (29.5% versus 11.7% among men, p < 0.001). The prevalence of major depression was 6% in the overall sample and there was no difference in the prevalence among sexes (5.8% among men versus 6.6 % among women). Obesity, daytime sleepiness, low physical activity, initial and late insomnia, low quality of life, and sleep medication and antidepressant use were all related to depression, whereas OSA severity, as measured by apnea-hypopnea index or oxygen desaturation index, was not. Daytime sleepiness, initial insomnia, and sleep medication use were the strongest predictors of depression in multivariable analyses. Sleep medication use, daytime sleepiness, and symptoms of initial insomnia were independently related to depression but OSA severity was not. Increased awareness of the relationship between depression and OSA and the appropriate use of assessment tools might substantially improve diagnostic accuracy as well as treatment outcome for both disorders. Eimskip Fund of the University of Iceland Landspitali University Hospital Research Fund/HL94307