Vitamin D Intake and Status in 6-Year-Old Icelandic Children Followed up from Infancy.

• Published in: Nutrients
• Main Authors: Thorisdottir, Birna, Gunnarsdottir, Ingibjorg, Steingrimsdottir, Laufey, Palsson, Gestur I, Birgisdottir, Bryndis E, Thorsdottir, Inga
• Other Authors: 1 Univ Iceland, Sch Hlth Sci, Fac Food Sci & Nutr, Unit Nutr Res, IS-101 Reykjavik, Iceland 2 Landspitali Univ Hosp, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 3 Landspitali Univ Hosp, Childrens Hosp, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital
• Format: Article in Journal/Newspaper
• Language: English
• Published: MDPI AG 2016
• Subjects: D vítamín; Börn; NUR12; PED12; 25-Hydroxyvitamin D 2; Child; Dietary Supplements; Seasons; Vitamin D; Iceland
• Online Access: http://hdl.handle.net/2336/607200; https://doi.org/10.3390/nu8020075

To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. High serum 25-hydroxyvitamin D (25(OH)D) levels have been observed in infants in Nordic countries, likely due to vitamin D supplement use. Internationally, little is known about tracking vitamin D status from infancy to childhood. Following up 1-year-old infants in our national longitudinal cohort, our aims were to study vitamin D intake and status in healthy 6-year-old Icelandic children (n = 139) and to track vitamin D status from one year of age. At six years, the mean 25(OH)D level was 56.5 nmol/L (SD 17.9) and 64% of children were vitamin D sufficient (25(OH)D ≥ 50 nmol/L). A logistic regression model adjusted for gender and breastfeeding showed that higher total vitamin D intake (Odds ratio (OR) = 1.27, 95% confidence interval (CI) = 1.08-1.49), blood samples collected in summer (OR = 8.88, 95% CI = 1.83-43.23) or autumn (OR = 5.64, 95% CI = 1.16-27.32) compared to winter/spring, and 25(OH)D at age one (OR = 1.02, 95% CI = 1.002-1.04) were independently associated with vitamin D sufficiency at age six. The correlation between 25(OH)D at age one and six was 0.34 (p = 0.003). Our findings suggest that vitamin D status in infancy, current vitamin D intake and season are predictors of vitamin D status in early school age children. Our finding of vitamin D status tracking from infancy to childhood provides motivation for further studies on tracking and its clinical significance. Icelandic Research Fund of the Icelandic Centre for Research University of Iceland Research Fund Landspitali University Hospital Research Fund