Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study.
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Radical cystectomy (RC) is the standard treatment for muscle-invasive bladder cancer. Postoperative complications are reported to be as high as 65%. The objective of this study was to invest...
Published in: | Scandinavian Journal of Urology |
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Taylor & Francis
2016
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Online Access: | http://hdl.handle.net/2336/606063 https://doi.org/10.3109/21681805.2015.1085088 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/606063 2023-05-15T16:48:45+02:00 Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. Björnsson, Oddur Gudmundsson, Eirikur Orri Marteinsson, Valur Thor Jonsson, Eirikur 1 Landspitali Univ Hosp, Dept Urol, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 2 Akureyri Hosp, Dept Surg, Reykjavik, Iceland 2016 http://hdl.handle.net/2336/606063 https://doi.org/10.3109/21681805.2015.1085088 en eng Taylor & Francis http://dx.doi.org/ 10.3109/21681805.2015.1085088 Scand J Urol. 2016, 50 (1):65-70 2168-1813 26390011 doi:10.3109/21681805.2015.1085088 http://hdl.handle.net/2336/606063 Scandinavian journal of urology Archived with thanks to Scandinavian journal of urology Open Access - Opinn aðgangur Þvagblaðra Krabbamein Lífslíkur URS12 Urinary Bladder Neoplasms/complications Cystectomy Survival Article 2016 ftlandspitaliuni https://doi.org/10.3109/21681805.2015.1085088 2022-05-29T08:22:09Z To access publisher's full text version of this article click on the hyperlink at the bottom of the page Radical cystectomy (RC) is the standard treatment for muscle-invasive bladder cancer. Postoperative complications are reported to be as high as 65%. The objective of this study was to investigate complications and survival in Icelandic patients with bladder cancer who underwent RC. All patients who had bladder cancer and underwent RC in Iceland from 2003 to 2012 were included. Information was obtained retrospectively from patients' medical records and from the Icelandic Cause of Death Registry. Complications were classified according to the Clavien-Dindo classification system. The Kaplan-Meier method was used in the survival analysis. Only patients with transitional cell carcinoma (TCC) were included in the survival analysis. Overall, 108 patients (male 81%, median age 68 years) underwent the procedure during the study period and 100 of them had TCC. Ileal conduit was performed in 86% of procedures and orthotopic neobladder in 14%. The median operation time was 266 min and the median blood loss during the procedure was 1000 ml. No patient died within 30 days of surgery, but one patient (0.9%) died within 90 days of surgery from complications of the surgery. Complications were reported for 62 patients (57%) overall. Major complications (Clavien 3-5) were reported in 32 patients (29%), and 30 patients (28%) had only minor complications (Clavien 1-2). Twenty-four patients (22%) had to undergo reoperation. Overall 5 year survival was 54%. Morbidity after RC is high but similar to that seen in other studies. Long-term survival of Icelandic patients is comparable to that in neighboring countries. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Meier ENVELOPE(-45.900,-45.900,-60.633,-60.633) Scandinavian Journal of Urology 50 1 65 70 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Þvagblaðra Krabbamein Lífslíkur URS12 Urinary Bladder Neoplasms/complications Cystectomy Survival |
spellingShingle |
Þvagblaðra Krabbamein Lífslíkur URS12 Urinary Bladder Neoplasms/complications Cystectomy Survival Björnsson, Oddur Gudmundsson, Eirikur Orri Marteinsson, Valur Thor Jonsson, Eirikur Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
topic_facet |
Þvagblaðra Krabbamein Lífslíkur URS12 Urinary Bladder Neoplasms/complications Cystectomy Survival |
description |
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Radical cystectomy (RC) is the standard treatment for muscle-invasive bladder cancer. Postoperative complications are reported to be as high as 65%. The objective of this study was to investigate complications and survival in Icelandic patients with bladder cancer who underwent RC. All patients who had bladder cancer and underwent RC in Iceland from 2003 to 2012 were included. Information was obtained retrospectively from patients' medical records and from the Icelandic Cause of Death Registry. Complications were classified according to the Clavien-Dindo classification system. The Kaplan-Meier method was used in the survival analysis. Only patients with transitional cell carcinoma (TCC) were included in the survival analysis. Overall, 108 patients (male 81%, median age 68 years) underwent the procedure during the study period and 100 of them had TCC. Ileal conduit was performed in 86% of procedures and orthotopic neobladder in 14%. The median operation time was 266 min and the median blood loss during the procedure was 1000 ml. No patient died within 30 days of surgery, but one patient (0.9%) died within 90 days of surgery from complications of the surgery. Complications were reported for 62 patients (57%) overall. Major complications (Clavien 3-5) were reported in 32 patients (29%), and 30 patients (28%) had only minor complications (Clavien 1-2). Twenty-four patients (22%) had to undergo reoperation. Overall 5 year survival was 54%. Morbidity after RC is high but similar to that seen in other studies. Long-term survival of Icelandic patients is comparable to that in neighboring countries. |
author2 |
1 Landspitali Univ Hosp, Dept Urol, IS-101 Reykjavik, Iceland Organization-Enhanced Name(s) Landspitali National University Hospital 2 Akureyri Hosp, Dept Surg, Reykjavik, Iceland |
format |
Article in Journal/Newspaper |
author |
Björnsson, Oddur Gudmundsson, Eirikur Orri Marteinsson, Valur Thor Jonsson, Eirikur |
author_facet |
Björnsson, Oddur Gudmundsson, Eirikur Orri Marteinsson, Valur Thor Jonsson, Eirikur |
author_sort |
Björnsson, Oddur |
title |
Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
title_short |
Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
title_full |
Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
title_fullStr |
Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
title_full_unstemmed |
Radical cystectomy in the treatment of bladder cancer in Iceland: A population-based study. |
title_sort |
radical cystectomy in the treatment of bladder cancer in iceland: a population-based study. |
publisher |
Taylor & Francis |
publishDate |
2016 |
url |
http://hdl.handle.net/2336/606063 https://doi.org/10.3109/21681805.2015.1085088 |
long_lat |
ENVELOPE(-45.900,-45.900,-60.633,-60.633) |
geographic |
Meier |
geographic_facet |
Meier |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/ 10.3109/21681805.2015.1085088 Scand J Urol. 2016, 50 (1):65-70 2168-1813 26390011 doi:10.3109/21681805.2015.1085088 http://hdl.handle.net/2336/606063 Scandinavian journal of urology |
op_rights |
Archived with thanks to Scandinavian journal of urology Open Access - Opinn aðgangur |
op_doi |
https://doi.org/10.3109/21681805.2015.1085088 |
container_title |
Scandinavian Journal of Urology |
container_volume |
50 |
container_issue |
1 |
container_start_page |
65 |
op_container_end_page |
70 |
_version_ |
1766038831290646528 |