Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study.
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. The aim of this study was to investigate the associations between loss of a life partner a...
Published in: | American Journal of Epidemiology |
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Main Authors: | , , , , , , , , , , , |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Oxford Univ Press
2015
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Online Access: | http://hdl.handle.net/2336/552697 https://doi.org/10.1093/aje/kwt321 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
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language |
English |
topic |
Elliglöp Ekkjur Aged 80 and over Apolipoproteins E Cognition Dementia Executive Function Female Humans Iceland Male Memory Mild Cognitive Impairment Sex Factors Socioeconomic Factors Stress Psychological Time Factors Widowhood |
spellingShingle |
Elliglöp Ekkjur Aged 80 and over Apolipoproteins E Cognition Dementia Executive Function Female Humans Iceland Male Memory Mild Cognitive Impairment Sex Factors Socioeconomic Factors Stress Psychological Time Factors Widowhood Vidarsdottir, Halldora Fang, Fang Chang, Milan Aspelund, Thor Fall, Katja Jonsdottir, Maria K Jonsson, Palmi V Cotch, Mary Frances Harris, Tamara B Launer, Lenore J Gudnason, Vilmundur Valdimarsdottir, Unnur Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
topic_facet |
Elliglöp Ekkjur Aged 80 and over Apolipoproteins E Cognition Dementia Executive Function Female Humans Iceland Male Memory Mild Cognitive Impairment Sex Factors Socioeconomic Factors Stress Psychological Time Factors Widowhood |
description |
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. The aim of this study was to investigate the associations between loss of a life partner and the development of dementia and decline in cognitive function in later life. We used an Icelandic cohort of 4,370 participants in the Age, Gene/Environment Susceptibility-Reykjavik Study who were living as married in 1978 (born in 1907-1935) and were either still married (unexposed cohort) or widowed (exposed cohort) at follow-up (in 2002-2006). We ascertained history of marital status and spouse's death by record linkage to the Registry of the Total Population, Statistics Iceland. The outcome measures were as follows: 1) dementia and mild cognitive impairment; and 2) memory, speed of processing, and executive function. During the observation period, 3,007 individuals remained married and 1,363 lost a spouse through death. We did not find any significant associations between loss of a spouse and our outcome variables, except that widowed women had poorer executive function (mean = -0.08) during the first 2 years after their husbands' deaths compared with still-married women (mean = 0.09). Our findings do not support the notion that the risk of dementia is increased following the loss of a spouse, yet women demonstrate a seemingly temporary decline in executive function following the death of a partner. University of Iceland Research Fund for Graduate Students Icelandic Research Fund for Graduate Students (Rannis) Memorial Fund of Helga Jonsdottir and Sigurlidi Kristjansson Research Fund of Oldrunarrad Islands Icelandic Gerontological Society Research Fund Fund of Gudmundur Andresson Swedish Society for Medical Research National Institute on Aging N01-AG-1-2100 National Institute on Aging Icelandic Parliament Icelandic Heart Association |
author2 |
Addresses: Show the Organization-Enhanced name(s) 1 Univ Iceland, Ctr Publ Hlth Sci, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 2 Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden Show the Organization-Enhanced name(s) 3 Natl Univ Hosp Reykjavik, Geriatr Res Ctr, Reykjavik, Iceland Show the Organization-Enhanced name(s) 4 Reykjavik Univ, Sch Sci & Engn, Dept Sports Sci, Reykjavik, Iceland 5 Iceland Heart Assoc, Kopavogur, Iceland Show the Organization-Enhanced name(s) 6 Orebro Univ Hosp, Dept Clin Epidemiol & Biostat, Orebro, Sweden Show the Organization-Enhanced name(s) 7 Univ Iceland, Fac Psychol, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 8 Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 9 Natl Univ Hosp Reykjavik, Dept Geriatr, Reykjavik, Iceland Show the Organization-Enhanced name(s) 10 NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 11 NIA, Lab Epidemiol Demog & Biometry, NIH, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 12 Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA |
format |
Article in Journal/Newspaper |
author |
Vidarsdottir, Halldora Fang, Fang Chang, Milan Aspelund, Thor Fall, Katja Jonsdottir, Maria K Jonsson, Palmi V Cotch, Mary Frances Harris, Tamara B Launer, Lenore J Gudnason, Vilmundur Valdimarsdottir, Unnur |
author_facet |
Vidarsdottir, Halldora Fang, Fang Chang, Milan Aspelund, Thor Fall, Katja Jonsdottir, Maria K Jonsson, Palmi V Cotch, Mary Frances Harris, Tamara B Launer, Lenore J Gudnason, Vilmundur Valdimarsdottir, Unnur |
author_sort |
Vidarsdottir, Halldora |
title |
Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
title_short |
Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
title_full |
Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
title_fullStr |
Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
title_full_unstemmed |
Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. |
title_sort |
spousal loss and cognitive function in later life: a 25-year follow-up in the ages-reykjavik study. |
publisher |
Oxford Univ Press |
publishDate |
2015 |
url |
http://hdl.handle.net/2336/552697 https://doi.org/10.1093/aje/kwt321 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/ 10.1093/aje/kwt321 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939848/ 2014, 179 (6):674-83 Am. J. Epidemiol. 1476-6256 24444551 doi:10.1093/aje/kwt321 http://hdl.handle.net/2336/552697 American journal of epidemiology |
op_rights |
Archived with thanks to American journal of epidemiology Open Access |
op_doi |
https://doi.org/10.1093/aje/kwt321 |
container_title |
American Journal of Epidemiology |
container_volume |
179 |
container_issue |
6 |
container_start_page |
674 |
op_container_end_page |
683 |
_version_ |
1766038156549816320 |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/552697 2023-05-15T16:48:03+02:00 Spousal loss and cognitive function in later life: a 25-year follow-up in the AGES-Reykjavik study. Vidarsdottir, Halldora Fang, Fang Chang, Milan Aspelund, Thor Fall, Katja Jonsdottir, Maria K Jonsson, Palmi V Cotch, Mary Frances Harris, Tamara B Launer, Lenore J Gudnason, Vilmundur Valdimarsdottir, Unnur Addresses: Show the Organization-Enhanced name(s) 1 Univ Iceland, Ctr Publ Hlth Sci, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 2 Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden Show the Organization-Enhanced name(s) 3 Natl Univ Hosp Reykjavik, Geriatr Res Ctr, Reykjavik, Iceland Show the Organization-Enhanced name(s) 4 Reykjavik Univ, Sch Sci & Engn, Dept Sports Sci, Reykjavik, Iceland 5 Iceland Heart Assoc, Kopavogur, Iceland Show the Organization-Enhanced name(s) 6 Orebro Univ Hosp, Dept Clin Epidemiol & Biostat, Orebro, Sweden Show the Organization-Enhanced name(s) 7 Univ Iceland, Fac Psychol, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 8 Univ Iceland, Fac Med, IS-101 Reykjavik, Iceland Show the Organization-Enhanced name(s) 9 Natl Univ Hosp Reykjavik, Dept Geriatr, Reykjavik, Iceland Show the Organization-Enhanced name(s) 10 NEI, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 11 NIA, Lab Epidemiol Demog & Biometry, NIH, Bethesda, MD 20892 USA Show the Organization-Enhanced name(s) 12 Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA 2015 http://hdl.handle.net/2336/552697 https://doi.org/10.1093/aje/kwt321 en eng Oxford Univ Press http://dx.doi.org/ 10.1093/aje/kwt321 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3939848/ 2014, 179 (6):674-83 Am. J. Epidemiol. 1476-6256 24444551 doi:10.1093/aje/kwt321 http://hdl.handle.net/2336/552697 American journal of epidemiology Archived with thanks to American journal of epidemiology Open Access Elliglöp Ekkjur Aged 80 and over Apolipoproteins E Cognition Dementia Executive Function Female Humans Iceland Male Memory Mild Cognitive Impairment Sex Factors Socioeconomic Factors Stress Psychological Time Factors Widowhood Article 2015 ftlandspitaliuni https://doi.org/10.1093/aje/kwt321 2022-05-29T08:22:05Z To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files. This article is open access. The aim of this study was to investigate the associations between loss of a life partner and the development of dementia and decline in cognitive function in later life. We used an Icelandic cohort of 4,370 participants in the Age, Gene/Environment Susceptibility-Reykjavik Study who were living as married in 1978 (born in 1907-1935) and were either still married (unexposed cohort) or widowed (exposed cohort) at follow-up (in 2002-2006). We ascertained history of marital status and spouse's death by record linkage to the Registry of the Total Population, Statistics Iceland. The outcome measures were as follows: 1) dementia and mild cognitive impairment; and 2) memory, speed of processing, and executive function. During the observation period, 3,007 individuals remained married and 1,363 lost a spouse through death. We did not find any significant associations between loss of a spouse and our outcome variables, except that widowed women had poorer executive function (mean = -0.08) during the first 2 years after their husbands' deaths compared with still-married women (mean = 0.09). Our findings do not support the notion that the risk of dementia is increased following the loss of a spouse, yet women demonstrate a seemingly temporary decline in executive function following the death of a partner. University of Iceland Research Fund for Graduate Students Icelandic Research Fund for Graduate Students (Rannis) Memorial Fund of Helga Jonsdottir and Sigurlidi Kristjansson Research Fund of Oldrunarrad Islands Icelandic Gerontological Society Research Fund Fund of Gudmundur Andresson Swedish Society for Medical Research National Institute on Aging N01-AG-1-2100 National Institute on Aging Icelandic Parliament Icelandic Heart Association Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive American Journal of Epidemiology 179 6 674 683 |