Leghálskrabbameinsleit á Norðurlöndum til 1995 : könnun á nýgengi og dánartíðni, markaldri og bili milli skoðana

• Main Author: Kristján Sigurðsson
• Format: Article in Journal/Newspaper
• Language: Icelandic
• Published: Læknafélag Íslands, Læknafélag Reykjavíkur 2009
• Subjects: Leghálskrabbamein; Dánartíðni; Frumubreytingar; Kirtilkrabbamein; Uterine Cervical Neoplasms; Mass Screening; Adenocarcinoma; Mortality; Norway; Smella; Iceland
• Online Access: http://hdl.handle.net/2336/47193

Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Background: The objective of cervical cancer screening is to lower the incidence and mortality rates of the disease. The Nordic countries have a long experience in cervical cancer screening. Based on this experience this study evaluates the UICC and EC guidelines regarding the effectiveness of organized vs. spontaneous screening, targeted age groups and screening intervals. Material and methods: The study analyses the features of the Icelandic and the Nordic screening programmes and the observed trends in the incidence and mortality rates in these countries through 1995. It also analyses the trends for cytologic preinvasive lesions at first visit and at second and later visits after a normal test(s). The frequency of histologic lesions was calculated for the birth cohort 1920-1926 from the age of 60 and among women referred for colposcopic examination in 1994. Results: Organized screening started in all the Nordic countries except Norway soon after 1960. Up to 1985 the target age group and screening interval were most intensive in Iceland. All countries intensified the screening intervals after 1985. The reduction in both the mortality and the incidence rates was greatest in Iceland and Finland, intermediate in Sweden and Denmark, and lowest in Norway but in that country organized screening started in 1994. The age-specific incidence in the 20-29 age group has been increasing since 1971 in all the Nordic countries, except in Finland. In Iceland screening has greatly affected the rate of all stages of squamous cell carcinoma, but not the rate of adeno-and adenosquamous carcinomas. The prevalence of preinvasive disease has increased significantly since 1980. The rate of moderate to high-grade cytologic changes begins increasing as early as at 20 years of age and moderate to high-grade histologic lesions start to accumulate at 24 to 36 months after a normal smear. The rate of these lesions decreases with the number of ...