Increased disk size in glaucomatous eyes vs normal eyes in the Reykjavik eye study

• Published in: American Journal of Ophthalmology
• Main Authors: Wang, Lan, Damji, Karim F, Munger, Rejean, Jonasson, Fridbert, Arnarsson, Arsaell, Sasaki, Hiroshi, Sasaki, Kazuyuki
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier Science 2003
• Subjects: Comparative Study; Glaucoma; Open-Angle; Humans; Iceland; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Photography; ROC Curve; Research Support; Non-U.S. Gov't
• Online Access: http://hdl.handle.net/2336/4626; https://doi.org/10.1016/S0002-9394(02)01928-1

PURPOSE: To evaluate the use of disk diameter as an indicator in the identification of glaucomatous optic neuropathy. METHODS: We evaluated all available stereofundus photographs for 1,040 right eyes obtained in the Reykjavik Eye Study. Horizontal and vertical disk diameters were determined in a masked manner by a glaucoma specialist (K.F.D.). All disk diameters were corrected for refractive error. RESULTS: There were significant differences (P <.05) between the corrected vertical disk diameters of normal subjects (0.189 +/- 0.018 inches) and those suspected of having glaucoma (0.202 +/- 0.020 inches) as well as between the normal and the glaucoma groups (0.206 +/- 0.029 inches). The corrected horizontal measurement showed the same pattern. CONCLUSIONS: In the Reykjavik Eye Study, optic disks meeting structural criteria for glaucoma are significantly larger than normal nerves.