Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality.
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Excess childhood weight is associated with cardiovascular disease (CVD) in adulthood. Whether this is mediated through adult body mass index (BMI) and associated risk factors such as metabol...
Published in: | Nutrition, Metabolism and Cardiovascular Diseases |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Elsevier Science Ltd.
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Online Access: | http://hdl.handle.net/2336/325871 https://doi.org/10.1016/j.numecd.2014.01.001 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/325871 2023-05-15T16:49:39+02:00 Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. Imai, C M Gunnarsdottir, I Gudnason, V Aspelund, T Birgisdottir, B E Thorsdottir, I Halldorsson, T I Univ Iceland, Unit Nutr Res, IS-101 Reykjavik, Iceland, Landspitali Natl Univ Hosp, IS-101 Reykjavik, Iceland, Univ Iceland, Sch Hlth Sci, Fac Food Sci & Human Nutr, IS-101 Reykjavik, Iceland, Iceland Heart Assoc, IS-201 Kopavogur, Iceland, Univ Iceland, Sch Hlth Sci, Fac Med, IS-101 Reykjavik, Iceland 2014 http://hdl.handle.net/2336/325871 https://doi.org/10.1016/j.numecd.2014.01.001 en eng Elsevier Science Ltd. http://dx.doi.org/10.1016/j.numecd.2014.01.001 Nutr Metab Cardiovasc Dis. 2014, 24 (7):730-6 1590-3729 24560474 doi:10.1016/j.numecd.2014.01.001 http://hdl.handle.net/2336/325871 Nutrition, metabolism, and cardiovascular diseases : NMCD Archived with thanks to Nutrition, metabolism, and cardiovascular diseases : NMCD National Consortium - Landsaðgangur Offita Börn Hjartasjúkdómar Áhættuþættir Ísland Cardiovascular Diseases/etiology* Body Mass Index* Child Obesity/complications* Risk Factors Age Factors Cohort Studies Morbidity Adolescent Cardiovascular Diseases/epidemiology* Child Development* Female Follow-Up Studies Humans Iceland Longitudinal Studies Male Weight Gain* Article 2014 ftlandspitaliuni https://doi.org/10.1016/j.numecd.2014.01.001 2022-05-29T08:21:59Z To access publisher's full text version of this article click on the hyperlink at the bottom of the page Excess childhood weight is associated with cardiovascular disease (CVD) in adulthood. Whether this is mediated through adult body mass index (BMI) and associated risk factors such as metabolic derangements remains unclear. The aim was to examine whether childhood BMI velocity (Δkg m(-2) per year) was associated with adult CVD mortality and to examine how adult BMI and cardiometabolic risk factors contribute to the association. Subjects were 1924 Icelanders born between 1921 and 1935 and living in Reykjavik when recruited into a longitudinal study from 1967 to 1991. From ages 8-13 years, BMI velocity was calculated to quantify the association between childhood growth and adult CVD mortality. Deaths from recruitment to 31 December 2009 were extracted from the national register. There were 202 CVD deaths among men and 90 CVD deaths among women (mean follow-up: 25.9 years). Faster BMI velocity from ages 8-13 years was associated with CVD mortality when comparing those in the highest versus lowest tertile with corresponding hazard ratio (HR) (95% confidence interval (CI)): 1.49 (1.03, 2.15) among men and 2.32 (1.32, 4.08) among women after adjustment for mid-life BMI and CVD risk factors. Faster childhood BMI velocity was associated with elevated CVD risk factors among men at mid-life but these associations were less pronounced among women. Faster increase in BMI from ages 8-13 years was associated with an increased CVD mortality risk. Children with early growth spurts coupled with excess weight gain during this transition period from childhood into adolescence should be closely monitored to ensure better health in adulthood. University of Iceland Research Fund Landspitali National University Hospital Research Fund Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Nutrition, Metabolism and Cardiovascular Diseases 24 7 730 736 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Offita Börn Hjartasjúkdómar Áhættuþættir Ísland Cardiovascular Diseases/etiology* Body Mass Index* Child Obesity/complications* Risk Factors Age Factors Cohort Studies Morbidity Adolescent Cardiovascular Diseases/epidemiology* Child Development* Female Follow-Up Studies Humans Iceland Longitudinal Studies Male Weight Gain* |
spellingShingle |
Offita Börn Hjartasjúkdómar Áhættuþættir Ísland Cardiovascular Diseases/etiology* Body Mass Index* Child Obesity/complications* Risk Factors Age Factors Cohort Studies Morbidity Adolescent Cardiovascular Diseases/epidemiology* Child Development* Female Follow-Up Studies Humans Iceland Longitudinal Studies Male Weight Gain* Imai, C M Gunnarsdottir, I Gudnason, V Aspelund, T Birgisdottir, B E Thorsdottir, I Halldorsson, T I Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
topic_facet |
Offita Börn Hjartasjúkdómar Áhættuþættir Ísland Cardiovascular Diseases/etiology* Body Mass Index* Child Obesity/complications* Risk Factors Age Factors Cohort Studies Morbidity Adolescent Cardiovascular Diseases/epidemiology* Child Development* Female Follow-Up Studies Humans Iceland Longitudinal Studies Male Weight Gain* |
description |
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Excess childhood weight is associated with cardiovascular disease (CVD) in adulthood. Whether this is mediated through adult body mass index (BMI) and associated risk factors such as metabolic derangements remains unclear. The aim was to examine whether childhood BMI velocity (Δkg m(-2) per year) was associated with adult CVD mortality and to examine how adult BMI and cardiometabolic risk factors contribute to the association. Subjects were 1924 Icelanders born between 1921 and 1935 and living in Reykjavik when recruited into a longitudinal study from 1967 to 1991. From ages 8-13 years, BMI velocity was calculated to quantify the association between childhood growth and adult CVD mortality. Deaths from recruitment to 31 December 2009 were extracted from the national register. There were 202 CVD deaths among men and 90 CVD deaths among women (mean follow-up: 25.9 years). Faster BMI velocity from ages 8-13 years was associated with CVD mortality when comparing those in the highest versus lowest tertile with corresponding hazard ratio (HR) (95% confidence interval (CI)): 1.49 (1.03, 2.15) among men and 2.32 (1.32, 4.08) among women after adjustment for mid-life BMI and CVD risk factors. Faster childhood BMI velocity was associated with elevated CVD risk factors among men at mid-life but these associations were less pronounced among women. Faster increase in BMI from ages 8-13 years was associated with an increased CVD mortality risk. Children with early growth spurts coupled with excess weight gain during this transition period from childhood into adolescence should be closely monitored to ensure better health in adulthood. University of Iceland Research Fund Landspitali National University Hospital Research Fund |
author2 |
Univ Iceland, Unit Nutr Res, IS-101 Reykjavik, Iceland, Landspitali Natl Univ Hosp, IS-101 Reykjavik, Iceland, Univ Iceland, Sch Hlth Sci, Fac Food Sci & Human Nutr, IS-101 Reykjavik, Iceland, Iceland Heart Assoc, IS-201 Kopavogur, Iceland, Univ Iceland, Sch Hlth Sci, Fac Med, IS-101 Reykjavik, Iceland |
format |
Article in Journal/Newspaper |
author |
Imai, C M Gunnarsdottir, I Gudnason, V Aspelund, T Birgisdottir, B E Thorsdottir, I Halldorsson, T I |
author_facet |
Imai, C M Gunnarsdottir, I Gudnason, V Aspelund, T Birgisdottir, B E Thorsdottir, I Halldorsson, T I |
author_sort |
Imai, C M |
title |
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
title_short |
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
title_full |
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
title_fullStr |
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
title_full_unstemmed |
Faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
title_sort |
faster increase in body mass index between ages 8 and 13 is associated with risk factors for cardiovascular morbidity and mortality. |
publisher |
Elsevier Science Ltd. |
publishDate |
2014 |
url |
http://hdl.handle.net/2336/325871 https://doi.org/10.1016/j.numecd.2014.01.001 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1016/j.numecd.2014.01.001 Nutr Metab Cardiovasc Dis. 2014, 24 (7):730-6 1590-3729 24560474 doi:10.1016/j.numecd.2014.01.001 http://hdl.handle.net/2336/325871 Nutrition, metabolism, and cardiovascular diseases : NMCD |
op_rights |
Archived with thanks to Nutrition, metabolism, and cardiovascular diseases : NMCD National Consortium - Landsaðgangur |
op_doi |
https://doi.org/10.1016/j.numecd.2014.01.001 |
container_title |
Nutrition, Metabolism and Cardiovascular Diseases |
container_volume |
24 |
container_issue |
7 |
container_start_page |
730 |
op_container_end_page |
736 |
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1766039812948623360 |