Association of Morbus Ledderhose with Dupuytren's contracture.
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Fibromatous nodules in the sole of the foot are often called Ledderhose disease. It is a benign nodular formation in the plantar aponeurosis, typically at the distal medial border. A lump fo...
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Online Access: | http://hdl.handle.net/2336/324697 https://doi.org/10.1177/1071100713475352 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/324697 2023-05-15T16:49:08+02:00 Association of Morbus Ledderhose with Dupuytren's contracture. Gudmundsson, Kristján G Jónsson, Thorbjörn Arngrímsson, Reynir Reykjavik Primary Hlth Care, IS-104 Reykjavik, Iceland, Univ Iceland, Reykjavik, Iceland, Landspitali Univ Hosp, Blood Bank, Reykjavik, Iceland, Landspitali Univ Hosp, Dept Genet & Mol Med, Reykjavik, Iceland, Univ Iceland, Dept Biochem & Mol Biol, Biomed Ctr, IS-101 Reykjavik, Iceland 2013 http://hdl.handle.net/2336/324697 https://doi.org/10.1177/1071100713475352 en eng SAGE Publications http://dx.doi.org/10.1177/1071100713475352 http://fai.sagepub.com/content/34/6/841.full.pdf Foot Ankle Int. 2013, 34 (6):841-5 1071-1007 23386754 doi:10.1177/1071100713475352 http://hdl.handle.net/2336/324697 Foot & ankle international. / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society Archived with thanks to Foot & ankle international. / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society National Consortium - Landsaðgangur Fætur Æxli Hendur Age of Onset Case-Control Studies Dupuytren Contracture Fibroma Follow-Up Studies Foot Diseases Humans Iceland Male Article 2013 ftlandspitaliuni https://doi.org/10.1177/1071100713475352 2022-05-29T08:21:58Z To access publisher's full text version of this article click on the hyperlink at the bottom of the page Fibromatous nodules in the sole of the foot are often called Ledderhose disease. It is a benign nodular formation in the plantar aponeurosis, typically at the distal medial border. A lump forms and it can be a few centimeters in diameter. It is frequently seen as an isolated disease, but a relationship to Dupuytren's has been noted in some patients. The study was a part of a large cohort study, the Reykjavík study. Men with Dupuytren's disease (n = 122) were invited to follow-up 18 years after the initial observation. An equal number of controls, matched for age and smoking habits, were also invited. A total of 92 Dupuytren's patients and 101 control subjects attended for follow-up and were examined for plantar nodules. Statistical evaluation was carried out using chi-square test and presented as odds ratio (OR) and 95% confidence interval (95% CI). Ledderhose disease was identified in 14 of the 92 (15.2%) men with Dupuytren's disease, while it was only in 4 of the 101 (3.9%) matched controls (OR = 4.35, 95% CI, 1.3-16.7, P < 0.01). Men operated for Dupuytren's disease or with finger contractures were more likely to have plantar nodules than those with only nodules or strings in the palms (OR = 6.1, 95% CI, 1.8-27.1, P < 0.001). The plantar involvement was related to family history of Dupuytren's disease (OR = 3.1, 95% CI, 1.1-8.5, P = 0.02). Men with manifestations of finger contractures or who need surgery for Dupuytren's disease are more likely to also develop plantar fibromas. Level III, retrospective comparative series. Icelandic Centre for Research Science Fund of Family Physicians in Iceland Article in Journal/Newspaper Iceland Reykjavík Reykjavík Hirsla - Landspítali University Hospital research archive Reykjavík Foot & Ankle International 34 6 841 845 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Fætur Æxli Hendur Age of Onset Case-Control Studies Dupuytren Contracture Fibroma Follow-Up Studies Foot Diseases Humans Iceland Male |
spellingShingle |
Fætur Æxli Hendur Age of Onset Case-Control Studies Dupuytren Contracture Fibroma Follow-Up Studies Foot Diseases Humans Iceland Male Gudmundsson, Kristján G Jónsson, Thorbjörn Arngrímsson, Reynir Association of Morbus Ledderhose with Dupuytren's contracture. |
topic_facet |
Fætur Æxli Hendur Age of Onset Case-Control Studies Dupuytren Contracture Fibroma Follow-Up Studies Foot Diseases Humans Iceland Male |
description |
To access publisher's full text version of this article click on the hyperlink at the bottom of the page Fibromatous nodules in the sole of the foot are often called Ledderhose disease. It is a benign nodular formation in the plantar aponeurosis, typically at the distal medial border. A lump forms and it can be a few centimeters in diameter. It is frequently seen as an isolated disease, but a relationship to Dupuytren's has been noted in some patients. The study was a part of a large cohort study, the Reykjavík study. Men with Dupuytren's disease (n = 122) were invited to follow-up 18 years after the initial observation. An equal number of controls, matched for age and smoking habits, were also invited. A total of 92 Dupuytren's patients and 101 control subjects attended for follow-up and were examined for plantar nodules. Statistical evaluation was carried out using chi-square test and presented as odds ratio (OR) and 95% confidence interval (95% CI). Ledderhose disease was identified in 14 of the 92 (15.2%) men with Dupuytren's disease, while it was only in 4 of the 101 (3.9%) matched controls (OR = 4.35, 95% CI, 1.3-16.7, P < 0.01). Men operated for Dupuytren's disease or with finger contractures were more likely to have plantar nodules than those with only nodules or strings in the palms (OR = 6.1, 95% CI, 1.8-27.1, P < 0.001). The plantar involvement was related to family history of Dupuytren's disease (OR = 3.1, 95% CI, 1.1-8.5, P = 0.02). Men with manifestations of finger contractures or who need surgery for Dupuytren's disease are more likely to also develop plantar fibromas. Level III, retrospective comparative series. Icelandic Centre for Research Science Fund of Family Physicians in Iceland |
author2 |
Reykjavik Primary Hlth Care, IS-104 Reykjavik, Iceland, Univ Iceland, Reykjavik, Iceland, Landspitali Univ Hosp, Blood Bank, Reykjavik, Iceland, Landspitali Univ Hosp, Dept Genet & Mol Med, Reykjavik, Iceland, Univ Iceland, Dept Biochem & Mol Biol, Biomed Ctr, IS-101 Reykjavik, Iceland |
format |
Article in Journal/Newspaper |
author |
Gudmundsson, Kristján G Jónsson, Thorbjörn Arngrímsson, Reynir |
author_facet |
Gudmundsson, Kristján G Jónsson, Thorbjörn Arngrímsson, Reynir |
author_sort |
Gudmundsson, Kristján G |
title |
Association of Morbus Ledderhose with Dupuytren's contracture. |
title_short |
Association of Morbus Ledderhose with Dupuytren's contracture. |
title_full |
Association of Morbus Ledderhose with Dupuytren's contracture. |
title_fullStr |
Association of Morbus Ledderhose with Dupuytren's contracture. |
title_full_unstemmed |
Association of Morbus Ledderhose with Dupuytren's contracture. |
title_sort |
association of morbus ledderhose with dupuytren's contracture. |
publisher |
SAGE Publications |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/324697 https://doi.org/10.1177/1071100713475352 |
geographic |
Reykjavík |
geographic_facet |
Reykjavík |
genre |
Iceland Reykjavík Reykjavík |
genre_facet |
Iceland Reykjavík Reykjavík |
op_relation |
http://dx.doi.org/10.1177/1071100713475352 http://fai.sagepub.com/content/34/6/841.full.pdf Foot Ankle Int. 2013, 34 (6):841-5 1071-1007 23386754 doi:10.1177/1071100713475352 http://hdl.handle.net/2336/324697 Foot & ankle international. / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society |
op_rights |
Archived with thanks to Foot & ankle international. / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society National Consortium - Landsaðgangur |
op_doi |
https://doi.org/10.1177/1071100713475352 |
container_title |
Foot & Ankle International |
container_volume |
34 |
container_issue |
6 |
container_start_page |
841 |
op_container_end_page |
845 |
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1766039213990477824 |