Increasing incidence of candidemia: results from a 20-year nationwide study in Iceland

• Published in: Journal of Clinical Microbiology
• Main Authors: Asmundsdottir, Lena Ros, Erlendsdottir, Helga, Gottfredsson, Magnus
• Other Authors: University of Iceland, Reykjavik, Iceland.
• Format: Article in Journal/Newspaper
• Language: English
• Published: American Society for Microbiology 2008
• Subjects: Adolescent; Adult; Age Distribution; Aged; Antifungal Agents; Blood; Candida; Candida albicans; Candidiasis; Child; Preschool; Culture Media; Fungemia; Humans; Iceland; Incidence; Infant; Microbial Sensitivity Tests; Middle Aged
• Online Access: http://hdl.handle.net/2336/32393; https://doi.org/10.1128/JCM.40.9.3489-3492.2002

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field A nationwide study on candidemia was conducted in Iceland from 1980 to 1999. The annual incidence increased from 1.4 cases/100,000 inhabitants/year between 1980 and 1984 to 4.9 cases/100,000 inhabitants/year between 1995 and 1999 (P < 0.0001). Candidemia episodes at university hospitals increased from 0.15/1,000 admissions to 0.55/1,000 admissions (P < 0.0001). Candida albicans was the predominant species responsible (64.4%). The national import of fluconazole increased approximately fourfold during the second half of the study, but increased resistance to this agent was not observed.