Glomerular filtration rate after a 12-wk resistance exercise program with post-exercise protein ingestion in community dwelling elderly.

• Published in: Nutrition
• Main Authors: Ramel, Alfons, Arnarson, Atli, Geirsdottir, Olof G, Jonsson, Palmi V, Thorsdottir, Inga
• Other Authors: Univ Iceland, Natl Univ Hosp, Unit Nutr Res, Reykjavik, Iceland, Univ Iceland, Fac Food Sci & Nutr, Reykjavik, Iceland, Univ Iceland, Natl Univ Hosp, Iceland Gerontol Res Ctr, Reykjavik, Iceland, Univ Iceland, Fac Med, Reykjavik, Iceland, Univ Iceland, Natl Univ Hosp, Dept Geriatr, Reykjavik, Iceland
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier Science Inc 2014
• Subjects: Mataræði; Prótín; Mjólk; Líkamsrækt; Nýru; Drykkir; Aldraðir; Lyftingar; Aged; 80 and over; Animals; Beverages; Diet; Dietary Carbohydrates; Dietary Proteins; Dietary Supplements; Energy Intake; Exercise; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Milk; Milk Proteins; Resistance Training; Weight Lifting; Iceland
• Online Access: http://hdl.handle.net/2336/322355; https://doi.org/10.1016/j.nut.2012.10.002

To access publisher's full text version of this article click on the hyperlink at the bottom of the page Increased protein intake and resistance exercise can be beneficial for maintenance of lean body mass (LBM) in older adults. However, these factors could also negatively affect renal function. We investigated changes in renal function after a 12-wk resistance exercise program combined with protein supplementation in community dwelling older adults. Patients (N = 237, 73.7 ± 5.7 y, 58.2% female) participated in a 12-wk resistance exercise program (3 times/wk) designed to increase strength and muscle mass of major muscle groups. Participants were randomly assigned to one of three dietary supplements consumed directly after training: whey protein drink (20 g whey protein, 20 g carbohydrates), milk protein drink (20 g milk protein, 20 g carbohydrates), or carbohydrate drink (40 g carbohydrates). Renal function was estimated as glomerular filtration rate (GFR, Cockcroft-Gault formula), and dietary intake was measured as 3-d-weighed food record at baseline and endpoint. During the intervention, energy intake did not increase. Carbohydrate intake increased in the carbohydrate group and protein intake increased in the milk group, both approximately in accordance with the supplementation. In the whey group, protein intake did not increase, but carbohydrate intake did. GFR increased after the intervention (+4.4 mL/min/1.73 m2; P < 0.001), and the changes were similar in men and women or in the age quartiles. Changes in GFR at endpoint were not associated with LBM, dietary supplements, or total protein intake. A 12-wk resistance exercise program combined with protein supplementation in community dwelling older adults does not negatively affect GFR. The supplementation had only minor effects on total dietary intake. Icelandic Technology Development Fund/ 071323008 University of Iceland Landspitali University Hospital Helga Jonsdottir and Sigurlidi Kristjansson Geriatric Research Fund