A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open The Alzheimer's Disease Assessment Scale (ADAS) is designed for screening of cognitive and non-cognitive dysfunctions characteristic of persons with probable Alzheimer's disease (AD). The cogni...
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Taylor & Francis Health Sciences
2008
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Online Access: | http://hdl.handle.net/2336/31494 https://doi.org/10.1080/080394802317607183 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/31494 2023-05-15T16:52:20+02:00 A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population Hannesdottir, Kristin Snaedal, Jon Memory Clinic, Department of Geriatrics, Landakot, University Hospital, Reykjavik, Iceland. 2008-07-10 http://hdl.handle.net/2336/31494 https://doi.org/10.1080/080394802317607183 en eng Taylor & Francis Health Sciences http://www.informaworld.com/10.1080/080394802317607183 Nord J Psychiatry. 2002, 56(3):201-6 0803-9488 12079572 doi:10.1080/080394802317607183 http://hdl.handle.net/2336/31494 Nordic journal of psychiatry Aged 80 and over Alzheimer Disease Cognition Disorders Female Humans Iceland Male Questionnaires Severity of Illness Index Article 2008 ftlandspitaliuni https://doi.org/10.1080/080394802317607183 2022-05-29T08:21:10Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open The Alzheimer's Disease Assessment Scale (ADAS) is designed for screening of cognitive and non-cognitive dysfunctions characteristic of persons with probable Alzheimer's disease (AD). The cognitive part of the scale (ADAS-Cog) is both convenient for screening of probable AD and as a measure of cognitive functioning during drug intervention. The aim of this study was to translate the ADAS-Cognitive sub-test (ADAS-Cog) into Icelandic and to study its application in an elderly Icelandic population. The Mini-Mental State Examination (MMSE) and the ADAS-Cog were administered to 20 AD patients and 20 controls. Each patient was also rated on the Global Deterioration Scale (GDS). The probable AD patients were divided into two groups based on their GDS: 3-4 and 5-6 points. The patients were also divided into two groups based on their MMSE score: very mild to mild (23-30 points) and mild to moderate (15-22 points). Furthermore, the subjects were divided into two age groups: 65-76 and 77-92 years. Results revealed a highly significant difference on MMSE (22.3 +/- 3.4; 26.8 +/- 1.6; P < 0.05) and ADAS-Cog (18.4 +/- 7.7; 7.3 +/- 3.5; P < 0.05) scores for patients and controls respectively. AD patients also performed significantly worse than the elderly control group on eight of the 11 sub-tests. Thus, the present findings are mainly in line with those of previous studies. The scale exceeds other screening tests such as the MMSE in that it addresses in more detail the symptoms of AD and is valuable for early detection of the illness and staging. ADAS-Cog plays an important role in the diagnostic makeup of AD along with other detailed investigations, such as neuropsychological assessment. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Smella ENVELOPE(29.443,29.443,69.896,69.896) Nordic Journal of Psychiatry 56 3 201 206 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Aged 80 and over Alzheimer Disease Cognition Disorders Female Humans Iceland Male Questionnaires Severity of Illness Index |
spellingShingle |
Aged 80 and over Alzheimer Disease Cognition Disorders Female Humans Iceland Male Questionnaires Severity of Illness Index Hannesdottir, Kristin Snaedal, Jon A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
topic_facet |
Aged 80 and over Alzheimer Disease Cognition Disorders Female Humans Iceland Male Questionnaires Severity of Illness Index |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open The Alzheimer's Disease Assessment Scale (ADAS) is designed for screening of cognitive and non-cognitive dysfunctions characteristic of persons with probable Alzheimer's disease (AD). The cognitive part of the scale (ADAS-Cog) is both convenient for screening of probable AD and as a measure of cognitive functioning during drug intervention. The aim of this study was to translate the ADAS-Cognitive sub-test (ADAS-Cog) into Icelandic and to study its application in an elderly Icelandic population. The Mini-Mental State Examination (MMSE) and the ADAS-Cog were administered to 20 AD patients and 20 controls. Each patient was also rated on the Global Deterioration Scale (GDS). The probable AD patients were divided into two groups based on their GDS: 3-4 and 5-6 points. The patients were also divided into two groups based on their MMSE score: very mild to mild (23-30 points) and mild to moderate (15-22 points). Furthermore, the subjects were divided into two age groups: 65-76 and 77-92 years. Results revealed a highly significant difference on MMSE (22.3 +/- 3.4; 26.8 +/- 1.6; P < 0.05) and ADAS-Cog (18.4 +/- 7.7; 7.3 +/- 3.5; P < 0.05) scores for patients and controls respectively. AD patients also performed significantly worse than the elderly control group on eight of the 11 sub-tests. Thus, the present findings are mainly in line with those of previous studies. The scale exceeds other screening tests such as the MMSE in that it addresses in more detail the symptoms of AD and is valuable for early detection of the illness and staging. ADAS-Cog plays an important role in the diagnostic makeup of AD along with other detailed investigations, such as neuropsychological assessment. |
author2 |
Memory Clinic, Department of Geriatrics, Landakot, University Hospital, Reykjavik, Iceland. |
format |
Article in Journal/Newspaper |
author |
Hannesdottir, Kristin Snaedal, Jon |
author_facet |
Hannesdottir, Kristin Snaedal, Jon |
author_sort |
Hannesdottir, Kristin |
title |
A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
title_short |
A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
title_full |
A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
title_fullStr |
A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
title_full_unstemmed |
A study of the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) in an Icelandic elderly population |
title_sort |
study of the alzheimer's disease assessment scale-cognitive (adas-cog) in an icelandic elderly population |
publisher |
Taylor & Francis Health Sciences |
publishDate |
2008 |
url |
http://hdl.handle.net/2336/31494 https://doi.org/10.1080/080394802317607183 |
long_lat |
ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Smella |
geographic_facet |
Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.informaworld.com/10.1080/080394802317607183 Nord J Psychiatry. 2002, 56(3):201-6 0803-9488 12079572 doi:10.1080/080394802317607183 http://hdl.handle.net/2336/31494 Nordic journal of psychiatry |
op_doi |
https://doi.org/10.1080/080394802317607183 |
container_title |
Nordic Journal of Psychiatry |
container_volume |
56 |
container_issue |
3 |
container_start_page |
201 |
op_container_end_page |
206 |
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1766042475662671872 |