Indications and surgical outcome following pulmonary metastasectomy: a nationwide study.
The aim of this retrospective nationwide study was to investigate indications and surgical outcome after pulmonary metastasectomy (PM) in a well-defined cohort of patients and to calculate the proportion of cancer patients who were operated on. Between 1984 and 2008, 81 patients (age 54.8 years, 50....
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/302011 2023-05-15T16:47:43+02:00 Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. Vidarsdottir, Halla Moller, Pall H Jonasson, Jon G Pfannschmidt, Joachim Gudbjartsson, Tomas Department of Surgery, Landspitali University Hospital, Reykjavik, Iceland. 2013-09-20 http://hdl.handle.net/2336/302011 https://doi.org/10.1055/s-0031-1293602 en eng Thieme http://dx.doi.org/10.1055/s-0031-1293602 Thorac Cardiovasc Surg 2012, 60(6):383-9 1439-1902 22215491 doi:10.1055/s-0031-1293602 http://hdl.handle.net/2336/302011 Thoracic and cardiovascular surgeon Archived with thanks to The Thoracic and cardiovascular surgeon Closed - Lokað Adolescent Adult Aged 80 and over Carcinoma Renal Cell Chi-Square Distribution Child Preschool Colorectal Neoplasms Disease-Free Survival Female Hospital Mortality Humans Iceland Kaplan-Meier Estimate Kidney Neoplasms Lung Neoplasms Male Metastasectomy Middle Aged Pneumonectomy Registries Retrospective Studies Risk Assessment Risk Factors Sarcoma Time Factors Treatment Outcome Young Adult Article 2013 ftlandspitaliuni https://doi.org/10.1055/s-0031-1293602 2022-05-29T08:21:52Z The aim of this retrospective nationwide study was to investigate indications and surgical outcome after pulmonary metastasectomy (PM) in a well-defined cohort of patients and to calculate the proportion of cancer patients who were operated on. Between 1984 and 2008, 81 patients (age 54.8 years, 50.6% men) underwent 100 PMs with curative intent in Iceland. For all patients, information on demographics, number of metastases, type of surgery, and complications were collected. Overall survival was estimated with median follow-up of 45 months. For the three most common malignancies, the proportion of patients who underwent PM was calculated using information from the Icelandic Cancer Registry on all cases diagnosed. Of 100 PMs, there were 62 wedge resections, 34 lobectomies, and 4 pneumonectomies. The most common complication was persistent air leakage (>96 hour; 11.1%), and operative mortality was 1.2%. Of the 12 kinds of primary malignancies operated, three were most common: colorectal carcinoma (CRC, n = 27), sarcoma (n = 21), and renal cell carcinoma (RCC, n = 14). The proportion of patients who underwent PM was 1.0% for CRC, 6.5% for sarcoma, and 1.4% for RCC, and their 5-year overall survival was 45.2, 18.6, and 38.5%, respectively (p = 0.11). Survival for all patients was 30.8%. The surgical outcome and survival of patients who underwent PM in Iceland are comparable to those in the other studies. Although there was no control group and selection bias cannot be eliminated, the survival of PM patients was better than for the nonoperated patients. However, a relatively small proportion of patients with CRC, RCC, and sarcoma underwent metastasectomy. Landspitali Research Fund Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Meier ENVELOPE(-45.900,-45.900,-60.633,-60.633) The Thoracic and Cardiovascular Surgeon 60 06 383 389 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Chi-Square Distribution Child Preschool Colorectal Neoplasms Disease-Free Survival Female Hospital Mortality Humans Iceland Kaplan-Meier Estimate Kidney Neoplasms Lung Neoplasms Male Metastasectomy Middle Aged Pneumonectomy Registries Retrospective Studies Risk Assessment Risk Factors Sarcoma Time Factors Treatment Outcome Young Adult |
spellingShingle |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Chi-Square Distribution Child Preschool Colorectal Neoplasms Disease-Free Survival Female Hospital Mortality Humans Iceland Kaplan-Meier Estimate Kidney Neoplasms Lung Neoplasms Male Metastasectomy Middle Aged Pneumonectomy Registries Retrospective Studies Risk Assessment Risk Factors Sarcoma Time Factors Treatment Outcome Young Adult Vidarsdottir, Halla Moller, Pall H Jonasson, Jon G Pfannschmidt, Joachim Gudbjartsson, Tomas Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
topic_facet |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Chi-Square Distribution Child Preschool Colorectal Neoplasms Disease-Free Survival Female Hospital Mortality Humans Iceland Kaplan-Meier Estimate Kidney Neoplasms Lung Neoplasms Male Metastasectomy Middle Aged Pneumonectomy Registries Retrospective Studies Risk Assessment Risk Factors Sarcoma Time Factors Treatment Outcome Young Adult |
description |
The aim of this retrospective nationwide study was to investigate indications and surgical outcome after pulmonary metastasectomy (PM) in a well-defined cohort of patients and to calculate the proportion of cancer patients who were operated on. Between 1984 and 2008, 81 patients (age 54.8 years, 50.6% men) underwent 100 PMs with curative intent in Iceland. For all patients, information on demographics, number of metastases, type of surgery, and complications were collected. Overall survival was estimated with median follow-up of 45 months. For the three most common malignancies, the proportion of patients who underwent PM was calculated using information from the Icelandic Cancer Registry on all cases diagnosed. Of 100 PMs, there were 62 wedge resections, 34 lobectomies, and 4 pneumonectomies. The most common complication was persistent air leakage (>96 hour; 11.1%), and operative mortality was 1.2%. Of the 12 kinds of primary malignancies operated, three were most common: colorectal carcinoma (CRC, n = 27), sarcoma (n = 21), and renal cell carcinoma (RCC, n = 14). The proportion of patients who underwent PM was 1.0% for CRC, 6.5% for sarcoma, and 1.4% for RCC, and their 5-year overall survival was 45.2, 18.6, and 38.5%, respectively (p = 0.11). Survival for all patients was 30.8%. The surgical outcome and survival of patients who underwent PM in Iceland are comparable to those in the other studies. Although there was no control group and selection bias cannot be eliminated, the survival of PM patients was better than for the nonoperated patients. However, a relatively small proportion of patients with CRC, RCC, and sarcoma underwent metastasectomy. Landspitali Research Fund |
author2 |
Department of Surgery, Landspitali University Hospital, Reykjavik, Iceland. |
format |
Article in Journal/Newspaper |
author |
Vidarsdottir, Halla Moller, Pall H Jonasson, Jon G Pfannschmidt, Joachim Gudbjartsson, Tomas |
author_facet |
Vidarsdottir, Halla Moller, Pall H Jonasson, Jon G Pfannschmidt, Joachim Gudbjartsson, Tomas |
author_sort |
Vidarsdottir, Halla |
title |
Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
title_short |
Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
title_full |
Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
title_fullStr |
Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
title_full_unstemmed |
Indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
title_sort |
indications and surgical outcome following pulmonary metastasectomy: a nationwide study. |
publisher |
Thieme |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/302011 https://doi.org/10.1055/s-0031-1293602 |
long_lat |
ENVELOPE(-45.900,-45.900,-60.633,-60.633) |
geographic |
Meier |
geographic_facet |
Meier |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1055/s-0031-1293602 Thorac Cardiovasc Surg 2012, 60(6):383-9 1439-1902 22215491 doi:10.1055/s-0031-1293602 http://hdl.handle.net/2336/302011 Thoracic and cardiovascular surgeon |
op_rights |
Archived with thanks to The Thoracic and cardiovascular surgeon Closed - Lokað |
op_doi |
https://doi.org/10.1055/s-0031-1293602 |
container_title |
The Thoracic and Cardiovascular Surgeon |
container_volume |
60 |
container_issue |
06 |
container_start_page |
383 |
op_container_end_page |
389 |
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1766037812441776128 |