Acute kidney injury in intensive care units according to RIFLE classification: a population-based study.
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Recent studies of the incidence of acute kidney injury (AKI) are largely based on estimated baseline serum creatinine values. The aim of this study was to more accurately determine...
Published in: | Acta Anaesthesiologica Scandinavica |
---|---|
Main Authors: | , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wiley-Blackwell
2013
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/301421 https://doi.org/10.1111/j.1399-6576.2012.02767.x |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301421 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301421 2023-05-15T16:49:08+02:00 Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. Sigurdsson, M I Vesteinsdottir, I O Sigvaldason, K Helgadottir, S Indridason, O S Sigurdsson, G H Department of Anaesthesia & Intensive Care Medicine, Landspitali University Hospital, Reykjavik, Iceland. 2013-09-10 http://hdl.handle.net/2336/301421 https://doi.org/10.1111/j.1399-6576.2012.02767.x en eng Wiley-Blackwell http://dx.doi.org/10.1111/j.1399-6576.2012.02767.x http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2012.02767.x/pdf Acta Anaesthesiol Scand 2012, 56(10):1291-7 1399-6576 22999042 doi:10.1111/j.1399-6576.2012.02767.x http://hdl.handle.net/2336/301421 Acta anaesthesiologica Scandinavica Archived with thanks to Acta anaesthesiologica Scandinavica National Consortium - Landsaðgangur Acute Kidney Injury Adolescent Adult Age Factors Aged 80 and over Confidence Intervals Creatinine Female Humans Iceland Intensive Care Units Kaplan-Meier Estimate Kidney Failure Chronic Male Middle Aged Population Renal Replacement Therapy Retrospective Studies Risk Factors Survival Young Adult Article 2013 ftlandspitaliuni https://doi.org/10.1111/j.1399-6576.2012.02767.x 2022-05-29T08:21:52Z To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Recent studies of the incidence of acute kidney injury (AKI) are largely based on estimated baseline serum creatinine values. The aim of this study was to more accurately determine the incidence of AKI using the RIFLE criteria for intensive care unit (ICU) patients of a whole population. All adult patients admitted to the ICUs of Landspitali - The National University Hospital of Iceland in 2007 (n = 1026) were studied with meticulous search for baseline creatinine. The underlying risk factors and contributing causes for AKI were defined, and survival and ratio of end-stage renal failure evaluated. A measured baseline creatinine value was found for all but two patients with AKI. The incidence of AKI according to RIFLE criteria was 21.7% [95% confidence interval (CI): 19.0-24.1%], with 7.1% (95 CI: 5.6-8.9%), 6.8% (95 CI: 5.3-8.5%) and 7.8% (95 CI: 6.2-9.6%) in the risk, injury and failure subgroups. Using estimated baseline creatinine overestimated the incidence of AKI by 3.5%. The sensitivity and specificity of the RIFLE criteria using estimated baseline creatinine were 76% and 95%. Renal replacement therapy was required for 17% of the AKI patients. One year survival of AKI patients was 51%, but only 2.5% of patients surviving 90 days required chronic renal replacement therapy. The incidence of AKI in the ICU was lower than previously published, perhaps due to overestimation of AKI using estimated baseline creatinine or bias from tertiary referrals. AKI patients have high mortality, but the survivors have a low incidence of end-stage renal failure. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Meier ENVELOPE(-45.900,-45.900,-60.633,-60.633) Acta Anaesthesiologica Scandinavica 56 10 1291 1297 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Acute Kidney Injury Adolescent Adult Age Factors Aged 80 and over Confidence Intervals Creatinine Female Humans Iceland Intensive Care Units Kaplan-Meier Estimate Kidney Failure Chronic Male Middle Aged Population Renal Replacement Therapy Retrospective Studies Risk Factors Survival Young Adult |
spellingShingle |
Acute Kidney Injury Adolescent Adult Age Factors Aged 80 and over Confidence Intervals Creatinine Female Humans Iceland Intensive Care Units Kaplan-Meier Estimate Kidney Failure Chronic Male Middle Aged Population Renal Replacement Therapy Retrospective Studies Risk Factors Survival Young Adult Sigurdsson, M I Vesteinsdottir, I O Sigvaldason, K Helgadottir, S Indridason, O S Sigurdsson, G H Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
topic_facet |
Acute Kidney Injury Adolescent Adult Age Factors Aged 80 and over Confidence Intervals Creatinine Female Humans Iceland Intensive Care Units Kaplan-Meier Estimate Kidney Failure Chronic Male Middle Aged Population Renal Replacement Therapy Retrospective Studies Risk Factors Survival Young Adult |
description |
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Recent studies of the incidence of acute kidney injury (AKI) are largely based on estimated baseline serum creatinine values. The aim of this study was to more accurately determine the incidence of AKI using the RIFLE criteria for intensive care unit (ICU) patients of a whole population. All adult patients admitted to the ICUs of Landspitali - The National University Hospital of Iceland in 2007 (n = 1026) were studied with meticulous search for baseline creatinine. The underlying risk factors and contributing causes for AKI were defined, and survival and ratio of end-stage renal failure evaluated. A measured baseline creatinine value was found for all but two patients with AKI. The incidence of AKI according to RIFLE criteria was 21.7% [95% confidence interval (CI): 19.0-24.1%], with 7.1% (95 CI: 5.6-8.9%), 6.8% (95 CI: 5.3-8.5%) and 7.8% (95 CI: 6.2-9.6%) in the risk, injury and failure subgroups. Using estimated baseline creatinine overestimated the incidence of AKI by 3.5%. The sensitivity and specificity of the RIFLE criteria using estimated baseline creatinine were 76% and 95%. Renal replacement therapy was required for 17% of the AKI patients. One year survival of AKI patients was 51%, but only 2.5% of patients surviving 90 days required chronic renal replacement therapy. The incidence of AKI in the ICU was lower than previously published, perhaps due to overestimation of AKI using estimated baseline creatinine or bias from tertiary referrals. AKI patients have high mortality, but the survivors have a low incidence of end-stage renal failure. |
author2 |
Department of Anaesthesia & Intensive Care Medicine, Landspitali University Hospital, Reykjavik, Iceland. |
format |
Article in Journal/Newspaper |
author |
Sigurdsson, M I Vesteinsdottir, I O Sigvaldason, K Helgadottir, S Indridason, O S Sigurdsson, G H |
author_facet |
Sigurdsson, M I Vesteinsdottir, I O Sigvaldason, K Helgadottir, S Indridason, O S Sigurdsson, G H |
author_sort |
Sigurdsson, M I |
title |
Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
title_short |
Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
title_full |
Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
title_fullStr |
Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
title_full_unstemmed |
Acute kidney injury in intensive care units according to RIFLE classification: a population-based study. |
title_sort |
acute kidney injury in intensive care units according to rifle classification: a population-based study. |
publisher |
Wiley-Blackwell |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/301421 https://doi.org/10.1111/j.1399-6576.2012.02767.x |
long_lat |
ENVELOPE(-45.900,-45.900,-60.633,-60.633) |
geographic |
Meier |
geographic_facet |
Meier |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1111/j.1399-6576.2012.02767.x http://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.2012.02767.x/pdf Acta Anaesthesiol Scand 2012, 56(10):1291-7 1399-6576 22999042 doi:10.1111/j.1399-6576.2012.02767.x http://hdl.handle.net/2336/301421 Acta anaesthesiologica Scandinavica |
op_rights |
Archived with thanks to Acta anaesthesiologica Scandinavica National Consortium - Landsaðgangur |
op_doi |
https://doi.org/10.1111/j.1399-6576.2012.02767.x |
container_title |
Acta Anaesthesiologica Scandinavica |
container_volume |
56 |
container_issue |
10 |
container_start_page |
1291 |
op_container_end_page |
1297 |
_version_ |
1766039212566511616 |