Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study.
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Understanding the determinants of health burden after a fracture in ageing populations is important. Assess the effect of clinical vertebral and other osteoporotic fractures on func...
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Online Access: | http://hdl.handle.net/2336/301397 https://doi.org/10.1093/ageing/afs003 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301397 2023-05-15T16:52:20+02:00 Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. Siggeirsdottir, Kristin Aspelund, Thor Jonsson, Brynjolfur Y Mogensen, Brynjolfur Launer, Lenore J Harris, Tamara B Sigurdsson, Gunnar Gudnason, Vilmundur Icelandic Heart Association Research Institute, Kopavogur, Iceland. 2013-09-10 http://hdl.handle.net/2336/301397 https://doi.org/10.1093/ageing/afs003 en eng Oxford University Press http://dx.doi.org/10.1093/ageing/afs003 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335370/pdf/afs003.pdf http://ageing.oxfordjournals.org/content/41/3/351 Age Ageing 2012, 41(3):351-7 1468-2834 22367357 doi:10.1093/ageing/afs003 http://hdl.handle.net/2336/301397 Age and ageing Archived with thanks to Age and ageing Open Access - Opinn aðgangur Activities of Daily Living Age Factors Aged 80 and over Aging Biomechanics Comorbidity Female Follow-Up Studies Hospitalization Humans Iceland Linear Models Male Muscle Strength Osteoporosis Proportional Hazards Models Prospective Studies Quality of Life Risk Assessment Risk Factors Spinal Fractures Time Factors Article 2013 ftlandspitaliuni https://doi.org/10.1093/ageing/afs003 2022-05-29T08:21:52Z To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Understanding the determinants of health burden after a fracture in ageing populations is important. Assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. A total of 5,764 individuals, 57.7% women, born 1907-35, mean age 77. Method: four groups with a verified fracture status were used; vertebral fractures, other osteoporotic fractures excluding vertebral, non-osteoporotic fractures and not-fractured were compared and analysed for the effect on mobility, strength, QoL, ADL, co-morbidity and hospitalisation. Worst performance on functional tests was in the vertebral fracture group for women (P < 0.0001) and the other osteoporotic fractures group for men (P < 0.05). Both vertebral and other osteoporotic fractures, showed an increased risk of hospitalisation, HR = 1.4 (95% CI: 1.3-1.7) and 1.2 (95% CI: 1.1-1.2) respectively (P < 0.0001). Individuals with vertebral fractures had 50% (P < 0.0001) longer hospitalisation than not-fractured and 33% (P < 0.002) longer than the other osteoporotic fractures group. Individuals with a history of clinical vertebral fracture seem to carry the greatest health burden compared with other fracture groups, emphasising the attention which should be given to those individuals. National Institutes of Health, USA N01-AG-12100 National Institute on Aging Hjartavernd (The Icelandic Heart Association) Althingi (The Icelandic Parliament) Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Age and Ageing 41 3 351 357 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Activities of Daily Living Age Factors Aged 80 and over Aging Biomechanics Comorbidity Female Follow-Up Studies Hospitalization Humans Iceland Linear Models Male Muscle Strength Osteoporosis Proportional Hazards Models Prospective Studies Quality of Life Risk Assessment Risk Factors Spinal Fractures Time Factors |
spellingShingle |
Activities of Daily Living Age Factors Aged 80 and over Aging Biomechanics Comorbidity Female Follow-Up Studies Hospitalization Humans Iceland Linear Models Male Muscle Strength Osteoporosis Proportional Hazards Models Prospective Studies Quality of Life Risk Assessment Risk Factors Spinal Fractures Time Factors Siggeirsdottir, Kristin Aspelund, Thor Jonsson, Brynjolfur Y Mogensen, Brynjolfur Launer, Lenore J Harris, Tamara B Sigurdsson, Gunnar Gudnason, Vilmundur Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
topic_facet |
Activities of Daily Living Age Factors Aged 80 and over Aging Biomechanics Comorbidity Female Follow-Up Studies Hospitalization Humans Iceland Linear Models Male Muscle Strength Osteoporosis Proportional Hazards Models Prospective Studies Quality of Life Risk Assessment Risk Factors Spinal Fractures Time Factors |
description |
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Understanding the determinants of health burden after a fracture in ageing populations is important. Assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. A total of 5,764 individuals, 57.7% women, born 1907-35, mean age 77. Method: four groups with a verified fracture status were used; vertebral fractures, other osteoporotic fractures excluding vertebral, non-osteoporotic fractures and not-fractured were compared and analysed for the effect on mobility, strength, QoL, ADL, co-morbidity and hospitalisation. Worst performance on functional tests was in the vertebral fracture group for women (P < 0.0001) and the other osteoporotic fractures group for men (P < 0.05). Both vertebral and other osteoporotic fractures, showed an increased risk of hospitalisation, HR = 1.4 (95% CI: 1.3-1.7) and 1.2 (95% CI: 1.1-1.2) respectively (P < 0.0001). Individuals with vertebral fractures had 50% (P < 0.0001) longer hospitalisation than not-fractured and 33% (P < 0.002) longer than the other osteoporotic fractures group. Individuals with a history of clinical vertebral fracture seem to carry the greatest health burden compared with other fracture groups, emphasising the attention which should be given to those individuals. National Institutes of Health, USA N01-AG-12100 National Institute on Aging Hjartavernd (The Icelandic Heart Association) Althingi (The Icelandic Parliament) |
author2 |
Icelandic Heart Association Research Institute, Kopavogur, Iceland. |
format |
Article in Journal/Newspaper |
author |
Siggeirsdottir, Kristin Aspelund, Thor Jonsson, Brynjolfur Y Mogensen, Brynjolfur Launer, Lenore J Harris, Tamara B Sigurdsson, Gunnar Gudnason, Vilmundur |
author_facet |
Siggeirsdottir, Kristin Aspelund, Thor Jonsson, Brynjolfur Y Mogensen, Brynjolfur Launer, Lenore J Harris, Tamara B Sigurdsson, Gunnar Gudnason, Vilmundur |
author_sort |
Siggeirsdottir, Kristin |
title |
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
title_short |
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
title_full |
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
title_fullStr |
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
title_full_unstemmed |
Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study. |
title_sort |
effect of vertebral fractures on function, quality of life and hospitalisation the ages-reykjavik study. |
publisher |
Oxford University Press |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/301397 https://doi.org/10.1093/ageing/afs003 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1093/ageing/afs003 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335370/pdf/afs003.pdf http://ageing.oxfordjournals.org/content/41/3/351 Age Ageing 2012, 41(3):351-7 1468-2834 22367357 doi:10.1093/ageing/afs003 http://hdl.handle.net/2336/301397 Age and ageing |
op_rights |
Archived with thanks to Age and ageing Open Access - Opinn aðgangur |
op_doi |
https://doi.org/10.1093/ageing/afs003 |
container_title |
Age and Ageing |
container_volume |
41 |
container_issue |
3 |
container_start_page |
351 |
op_container_end_page |
357 |
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1766042497972174848 |