Mortality after surgery in Europe: a 7 day cohort study.
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve c...
Published in: | The Lancet |
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Elsevier Science
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Online Access: | http://hdl.handle.net/2336/301239 https://doi.org/10.1016/S0140-6736(12)61148-9 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301239 2023-05-15T16:52:47+02:00 Mortality after surgery in Europe: a 7 day cohort study. Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew Sigurdsson, GH Karason, S Sigurbjörnsson, FT Sigurdardottir, EE Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. 2012-09-22 http://hdl.handle.net/2336/301239 https://doi.org/10.1016/S0140-6736(12)61148-9 en eng Elsevier Science http://dx.doi.org/10.1016/S0140-6736(12)61148-9 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493988/ Lancet 2012, 380(9847):1059-65 1474-547X 22998715 doi:10.1016/S0140-6736(12)61148-9 http://hdl.handle.net/2336/301239 Lancet Archived with thanks to Lancet Open Access - Opinn aðgangur Adult Aged Cohort Studies Critical Care Europe Female Hospital Mortality Hospitalization Humans Length of Stay Male Middle Aged Postoperative Care Surgical Procedures Operative Treatment Outcome Article 2012 ftlandspitaliuni https://doi.org/10.1016/S0140-6736(12)61148-9 2022-05-29T08:21:52Z To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ(2) and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. We included 46,539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9-3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0-3·0] for Iceland to 21·5% [16·9-26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19-1·05; p=0·06] for Finland to 6·92 [2·37-20·27; p=0·0004] for Poland). The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive The Lancet 380 9847 1059 1065 |
institution |
Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adult Aged Cohort Studies Critical Care Europe Female Hospital Mortality Hospitalization Humans Length of Stay Male Middle Aged Postoperative Care Surgical Procedures Operative Treatment Outcome |
spellingShingle |
Adult Aged Cohort Studies Critical Care Europe Female Hospital Mortality Hospitalization Humans Length of Stay Male Middle Aged Postoperative Care Surgical Procedures Operative Treatment Outcome Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew Sigurdsson, GH Karason, S Sigurbjörnsson, FT Sigurdardottir, EE Mortality after surgery in Europe: a 7 day cohort study. |
topic_facet |
Adult Aged Cohort Studies Critical Care Europe Female Hospital Mortality Hospitalization Humans Length of Stay Male Middle Aged Postoperative Care Surgical Procedures Operative Treatment Outcome |
description |
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Clinical outcomes after major surgery are poorly described at the national level. Evidence of heterogeneity between hospitals and health-care systems suggests potential to improve care for patients but this potential remains unconfirmed. The European Surgical Outcomes Study was an international study designed to assess outcomes after non-cardiac surgery in Europe. We did this 7 day cohort study between April 4 and April 11, 2011. We collected data describing consecutive patients aged 16 years and older undergoing inpatient non-cardiac surgery in 498 hospitals across 28 European nations. Patients were followed up for a maximum of 60 days. The primary endpoint was in-hospital mortality. Secondary outcome measures were duration of hospital stay and admission to critical care. We used χ(2) and Fisher's exact tests to compare categorical variables and the t test or the Mann-Whitney U test to compare continuous variables. Significance was set at p<0·05. We constructed multilevel logistic regression models to adjust for the differences in mortality rates between countries. We included 46,539 patients, of whom 1855 (4%) died before hospital discharge. 3599 (8%) patients were admitted to critical care after surgery with a median length of stay of 1·2 days (IQR 0·9-3·6). 1358 (73%) patients who died were not admitted to critical care at any stage after surgery. Crude mortality rates varied widely between countries (from 1·2% [95% CI 0·0-3·0] for Iceland to 21·5% [16·9-26·2] for Latvia). After adjustment for confounding variables, important differences remained between countries when compared with the UK, the country with the largest dataset (OR range from 0·44 [95% CI 0·19-1·05; p=0·06] for Finland to 6·92 [2·37-20·27; p=0·0004] for Poland). The mortality rate for patients undergoing inpatient non-cardiac surgery was higher than anticipated. Variations in mortality between countries suggest the need for ... |
author2 |
Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. |
format |
Article in Journal/Newspaper |
author |
Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew Sigurdsson, GH Karason, S Sigurbjörnsson, FT Sigurdardottir, EE |
author_facet |
Pearse, Rupert M Moreno, Rui P Bauer, Peter Pelosi, Paolo Metnitz, Philipp Spies, Claudia Vallet, Benoit Vincent, Jean-Louis Hoeft, Andreas Rhodes, Andrew Sigurdsson, GH Karason, S Sigurbjörnsson, FT Sigurdardottir, EE |
author_sort |
Pearse, Rupert M |
title |
Mortality after surgery in Europe: a 7 day cohort study. |
title_short |
Mortality after surgery in Europe: a 7 day cohort study. |
title_full |
Mortality after surgery in Europe: a 7 day cohort study. |
title_fullStr |
Mortality after surgery in Europe: a 7 day cohort study. |
title_full_unstemmed |
Mortality after surgery in Europe: a 7 day cohort study. |
title_sort |
mortality after surgery in europe: a 7 day cohort study. |
publisher |
Elsevier Science |
publishDate |
2012 |
url |
http://hdl.handle.net/2336/301239 https://doi.org/10.1016/S0140-6736(12)61148-9 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1016/S0140-6736(12)61148-9 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493988/ Lancet 2012, 380(9847):1059-65 1474-547X 22998715 doi:10.1016/S0140-6736(12)61148-9 http://hdl.handle.net/2336/301239 Lancet |
op_rights |
Archived with thanks to Lancet Open Access - Opinn aðgangur |
op_doi |
https://doi.org/10.1016/S0140-6736(12)61148-9 |
container_title |
The Lancet |
container_volume |
380 |
container_issue |
9847 |
container_start_page |
1059 |
op_container_end_page |
1065 |
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1766043187092127744 |