Retinal oximetry images must be standardized: a methodological analysis.
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Retinal vessel oximetry is a new technology and needs detailed methodological scrutiny. We determine (1) the repeatability of retinal vessel oxygen saturation measurements, (2) whet...
Published in: | Investigative Opthalmology & Visual Science |
---|---|
Main Authors: | , , , , , |
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Assoc Research Vision Ophthalmology
2013
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/301237 https://doi.org/10.1167/iovs.11-8621 |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301237 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/301237 2023-05-15T16:51:49+02:00 Retinal oximetry images must be standardized: a methodological analysis. Palsson, Olafur Geirsdottir, Asbjorg Hardarson, Sveinn Hakon Olafsdottir, Olof Birna Kristjansdottir, Jona Valgerdur Stefánsson, Einar University of Iceland, National University Hospital, Reykjavik, Iceland. 2013-09-06 http://hdl.handle.net/2336/301237 https://doi.org/10.1167/iovs.11-8621 en eng Assoc Research Vision Ophthalmology http://dx.doi.org/10.1167/iovs.11-8621 http://www.iovs.org/content/53/4/1729.long Invest. Ophthalmol. Vis. Sci. 2012, 53(4):1729-33 1552-5783 22395877 doi:10.1167/iovs.11-8621 http://hdl.handle.net/2336/301237 Investigative ophthalmology & visual science Archived with thanks to Investigative ophthalmology & visual science Open Access - Opinn aðgangur Adolescent Adult Arterioles Humans Oximetry Oxygen Oxygen Consumption Reproducibility of Results Retinal Vessels Venules Young Adult Article 2013 ftlandspitaliuni https://doi.org/10.1167/iovs.11-8621 2022-05-29T08:21:52Z To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Retinal vessel oximetry is a new technology and needs detailed methodological scrutiny. We determine (1) the repeatability of retinal vessel oxygen saturation measurements, (2) whether measured saturation is different between retinal quadrants, and (3) whether the angle of gaze changes measurements of the same vessels. Fundus oximetry images were obtained from 26 healthy individuals, 18 to 30 years old, using the Oxymap retinal oximeter. Oxygen saturation in the same vessel segments was compared between two similar images of each individual to determine repeatability. Vessel oxygen saturation was also compared between different quadrants of the retina in the same oximetry image. Finally, oxygen saturation measurements were made on the same vessel segments at different angles of gaze. Mean and standard deviation of saturation measurements was 93.1% ± 2.3% in arterioles and 64.9% ± 3.3% in venules. Standard deviation of repeated saturation measurements on the same vessel segment was 1.0% in arterioles and 1.4% in venules. Significant differences were seen between retinal quadrants. When angle of gaze was altered, measured saturation was lower in the same vessels when they were located in the inferior portion compared with other parts of the image (-1.3% ± 1.7%, P = 0.0004 in arterioles and -1.9 ± 2.4%, P = 0.0007 in venules). Retinal vessel oxygen saturation measurements are repeatable with a small standard deviation. When oximetry results are compared between time points or eyes, the imaging must be standardized and similar parts of the images analyzed. Icelandic Center for Research (Rannis) University of Iceland Research Fund Landspitali University Hospital Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Investigative Opthalmology & Visual Science 53 4 1729 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adolescent Adult Arterioles Humans Oximetry Oxygen Oxygen Consumption Reproducibility of Results Retinal Vessels Venules Young Adult |
spellingShingle |
Adolescent Adult Arterioles Humans Oximetry Oxygen Oxygen Consumption Reproducibility of Results Retinal Vessels Venules Young Adult Palsson, Olafur Geirsdottir, Asbjorg Hardarson, Sveinn Hakon Olafsdottir, Olof Birna Kristjansdottir, Jona Valgerdur Stefánsson, Einar Retinal oximetry images must be standardized: a methodological analysis. |
topic_facet |
Adolescent Adult Arterioles Humans Oximetry Oxygen Oxygen Consumption Reproducibility of Results Retinal Vessels Venules Young Adult |
description |
To access publisher's full text version of this article. Please click on the hyperlink in Additional Links field. Retinal vessel oximetry is a new technology and needs detailed methodological scrutiny. We determine (1) the repeatability of retinal vessel oxygen saturation measurements, (2) whether measured saturation is different between retinal quadrants, and (3) whether the angle of gaze changes measurements of the same vessels. Fundus oximetry images were obtained from 26 healthy individuals, 18 to 30 years old, using the Oxymap retinal oximeter. Oxygen saturation in the same vessel segments was compared between two similar images of each individual to determine repeatability. Vessel oxygen saturation was also compared between different quadrants of the retina in the same oximetry image. Finally, oxygen saturation measurements were made on the same vessel segments at different angles of gaze. Mean and standard deviation of saturation measurements was 93.1% ± 2.3% in arterioles and 64.9% ± 3.3% in venules. Standard deviation of repeated saturation measurements on the same vessel segment was 1.0% in arterioles and 1.4% in venules. Significant differences were seen between retinal quadrants. When angle of gaze was altered, measured saturation was lower in the same vessels when they were located in the inferior portion compared with other parts of the image (-1.3% ± 1.7%, P = 0.0004 in arterioles and -1.9 ± 2.4%, P = 0.0007 in venules). Retinal vessel oxygen saturation measurements are repeatable with a small standard deviation. When oximetry results are compared between time points or eyes, the imaging must be standardized and similar parts of the images analyzed. Icelandic Center for Research (Rannis) University of Iceland Research Fund Landspitali University Hospital |
author2 |
University of Iceland, National University Hospital, Reykjavik, Iceland. |
format |
Article in Journal/Newspaper |
author |
Palsson, Olafur Geirsdottir, Asbjorg Hardarson, Sveinn Hakon Olafsdottir, Olof Birna Kristjansdottir, Jona Valgerdur Stefánsson, Einar |
author_facet |
Palsson, Olafur Geirsdottir, Asbjorg Hardarson, Sveinn Hakon Olafsdottir, Olof Birna Kristjansdottir, Jona Valgerdur Stefánsson, Einar |
author_sort |
Palsson, Olafur |
title |
Retinal oximetry images must be standardized: a methodological analysis. |
title_short |
Retinal oximetry images must be standardized: a methodological analysis. |
title_full |
Retinal oximetry images must be standardized: a methodological analysis. |
title_fullStr |
Retinal oximetry images must be standardized: a methodological analysis. |
title_full_unstemmed |
Retinal oximetry images must be standardized: a methodological analysis. |
title_sort |
retinal oximetry images must be standardized: a methodological analysis. |
publisher |
Assoc Research Vision Ophthalmology |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/301237 https://doi.org/10.1167/iovs.11-8621 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1167/iovs.11-8621 http://www.iovs.org/content/53/4/1729.long Invest. Ophthalmol. Vis. Sci. 2012, 53(4):1729-33 1552-5783 22395877 doi:10.1167/iovs.11-8621 http://hdl.handle.net/2336/301237 Investigative ophthalmology & visual science |
op_rights |
Archived with thanks to Investigative ophthalmology & visual science Open Access - Opinn aðgangur |
op_doi |
https://doi.org/10.1167/iovs.11-8621 |
container_title |
Investigative Opthalmology & Visual Science |
container_volume |
53 |
container_issue |
4 |
container_start_page |
1729 |
_version_ |
1766041924190339072 |