Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital.
Air pollutants in Iceland's capital area include hydrogen sulfide (H2S) emissions from geothermal power plants, particle pollution (PM10) and traffic-related pollutants. Respiratory health effects of exposure to PM and traffic pollutants are well documented, yet this is one of the first studies...
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/297941 2023-05-15T16:49:08+02:00 Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. Carlsen, Hanne Krage Zoëga, Helga Valdimarsdóttir, Unnur Gíslason, Thórarinn Hrafnkelsson, Birgir Centre of Public Health Sciences, School of Health Sciences, University of Iceland, Stapi v/Hringbraut, 101 Reykjavik, Iceland. hkc1@hi.is 2013-08-12 http://hdl.handle.net/2336/297941 https://doi.org/10.1016/j.envres.2011.10.010 en eng http://dx.doi.org/10.1016/j.envres.2011.10.010 http://www.sciencedirect.com/science/article/pii/S0013935111002866 Environ. Res. 2012, 113:33-9 1096-0953 22264878 doi:10.1016/j.envres.2011.10.010 http://hdl.handle.net/2336/297941 Environmental research Archived with thanks to Environmental research National Consortium - Landsaðgangur Adult Aged 80 and over Air Pollutants Air Pollution Anti-Asthmatic Agents Asthma Drug Utilization Humans Hydrogen Sulfide Iceland Inhalation Exposure Lung Diseases Obstructive Middle Aged Nitrogen Dioxide Ozone Particulate Matter Poisson Distribution Registries Regression Analysis Risk Seasons Urban Population Weather Article 2013 ftlandspitaliuni https://doi.org/10.1016/j.envres.2011.10.010 2022-05-29T08:21:51Z Air pollutants in Iceland's capital area include hydrogen sulfide (H2S) emissions from geothermal power plants, particle pollution (PM10) and traffic-related pollutants. Respiratory health effects of exposure to PM and traffic pollutants are well documented, yet this is one of the first studies to investigate short-term health effects of ambient H2S exposure. The aim of this study was to investigate the associations between daily ambient levels of H2S, PM10, nitrogen dioxide (NO2) and ozone (O3), and the use of drugs for obstructive pulmonary diseases in adults in Iceland's capital area. The study period was 8 March 2006 to 31 December 2009. We used log-linear Poisson generalized additive regression models with cubic splines to estimate relative risks of individually dispensed drugs by air pollution levels. A three-day moving average of the exposure variables gave the best fit to the data. Final models included significant covariates adjusting for climate and influenza epidemics, as well as time-dependent variables. The three-day moving average of H2S and PM10 levels were positively associated with the number of individuals who were dispensed drugs at lag 3-5, corresponding to a 2.0% (95% confidence interval [CI] 0.4, 3.6) and 0.9% (95% CI 0.1, 1.8) per 10 μg/m3 pollutant concentration increase, respectively. Our findings indicated that intermittent increases in levels of particle matter from traffic and natural sources and ambient H2S levels were weakly associated with increased dispensing of drugs for obstructive pulmonary disease in Iceland's capital area. These weak associations could be confounded by unevaluated variables hence further studies are needed. Oddur Olafsson Memorial Fund Support and Memorial of the Icelandic Asthma and Allergy Society Icelandic Road Administration University of Iceland Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Environmental Research 113 33 39 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adult Aged 80 and over Air Pollutants Air Pollution Anti-Asthmatic Agents Asthma Drug Utilization Humans Hydrogen Sulfide Iceland Inhalation Exposure Lung Diseases Obstructive Middle Aged Nitrogen Dioxide Ozone Particulate Matter Poisson Distribution Registries Regression Analysis Risk Seasons Urban Population Weather |
spellingShingle |
Adult Aged 80 and over Air Pollutants Air Pollution Anti-Asthmatic Agents Asthma Drug Utilization Humans Hydrogen Sulfide Iceland Inhalation Exposure Lung Diseases Obstructive Middle Aged Nitrogen Dioxide Ozone Particulate Matter Poisson Distribution Registries Regression Analysis Risk Seasons Urban Population Weather Carlsen, Hanne Krage Zoëga, Helga Valdimarsdóttir, Unnur Gíslason, Thórarinn Hrafnkelsson, Birgir Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
topic_facet |
Adult Aged 80 and over Air Pollutants Air Pollution Anti-Asthmatic Agents Asthma Drug Utilization Humans Hydrogen Sulfide Iceland Inhalation Exposure Lung Diseases Obstructive Middle Aged Nitrogen Dioxide Ozone Particulate Matter Poisson Distribution Registries Regression Analysis Risk Seasons Urban Population Weather |
description |
Air pollutants in Iceland's capital area include hydrogen sulfide (H2S) emissions from geothermal power plants, particle pollution (PM10) and traffic-related pollutants. Respiratory health effects of exposure to PM and traffic pollutants are well documented, yet this is one of the first studies to investigate short-term health effects of ambient H2S exposure. The aim of this study was to investigate the associations between daily ambient levels of H2S, PM10, nitrogen dioxide (NO2) and ozone (O3), and the use of drugs for obstructive pulmonary diseases in adults in Iceland's capital area. The study period was 8 March 2006 to 31 December 2009. We used log-linear Poisson generalized additive regression models with cubic splines to estimate relative risks of individually dispensed drugs by air pollution levels. A three-day moving average of the exposure variables gave the best fit to the data. Final models included significant covariates adjusting for climate and influenza epidemics, as well as time-dependent variables. The three-day moving average of H2S and PM10 levels were positively associated with the number of individuals who were dispensed drugs at lag 3-5, corresponding to a 2.0% (95% confidence interval [CI] 0.4, 3.6) and 0.9% (95% CI 0.1, 1.8) per 10 μg/m3 pollutant concentration increase, respectively. Our findings indicated that intermittent increases in levels of particle matter from traffic and natural sources and ambient H2S levels were weakly associated with increased dispensing of drugs for obstructive pulmonary disease in Iceland's capital area. These weak associations could be confounded by unevaluated variables hence further studies are needed. Oddur Olafsson Memorial Fund Support and Memorial of the Icelandic Asthma and Allergy Society Icelandic Road Administration University of Iceland |
author2 |
Centre of Public Health Sciences, School of Health Sciences, University of Iceland, Stapi v/Hringbraut, 101 Reykjavik, Iceland. hkc1@hi.is |
format |
Article in Journal/Newspaper |
author |
Carlsen, Hanne Krage Zoëga, Helga Valdimarsdóttir, Unnur Gíslason, Thórarinn Hrafnkelsson, Birgir |
author_facet |
Carlsen, Hanne Krage Zoëga, Helga Valdimarsdóttir, Unnur Gíslason, Thórarinn Hrafnkelsson, Birgir |
author_sort |
Carlsen, Hanne Krage |
title |
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
title_short |
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
title_full |
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
title_fullStr |
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
title_full_unstemmed |
Hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in Iceland's capital. |
title_sort |
hydrogen sulfide and particle matter levels associated with increased dispensing of anti-asthma drugs in iceland's capital. |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/297941 https://doi.org/10.1016/j.envres.2011.10.010 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1016/j.envres.2011.10.010 http://www.sciencedirect.com/science/article/pii/S0013935111002866 Environ. Res. 2012, 113:33-9 1096-0953 22264878 doi:10.1016/j.envres.2011.10.010 http://hdl.handle.net/2336/297941 Environmental research |
op_rights |
Archived with thanks to Environmental research National Consortium - Landsaðgangur |
op_doi |
https://doi.org/10.1016/j.envres.2011.10.010 |
container_title |
Environmental Research |
container_volume |
113 |
container_start_page |
33 |
op_container_end_page |
39 |
_version_ |
1766039211304026112 |