5-year incidence of age-related maculopathy in the Reykjavik Eye Study
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To examine the age- and gender-specific 5-year incidence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik. DESIGN: Population-ba...
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/2797 2023-05-15T16:48:44+02:00 5-year incidence of age-related maculopathy in the Reykjavik Eye Study Jonasson, Fridbert Arnarsson, Arsaell Peto, Tunde Sasaki, Hiroshi Sasaki, Kazuyuki Bird, Alan C 2005-01-01 YES http://hdl.handle.net/2336/2797 https://doi.org/10.1016/j.ophtha.2004.07.020 en eng Elsevier http://www.sciencedirect.com/science/article/B6VT2-4DW8TFM-C/2/6f7ffff017416492ebcbd8d6b92e78cb Ophthalmology 2005, 112(1):132-8 0161-6420 15629833 doi:10.1016/j.ophtha.2004.07.020 OPH12 http://hdl.handle.net/2336/2797 1549-4713 Ophthalmology Research Support Non-U.S. Gov't Macular Degeneration Sex Distribution Age Distribution Aged 80 and over Middle Aged Iceland/epidemiology Male Female Population Surveillance Cohort Studies Prospective Studies Article 2005 ftlandspitaliuni https://doi.org/10.1016/j.ophtha.2004.07.020 2022-05-29T08:20:50Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To examine the age- and gender-specific 5-year incidence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik. DESIGN: Population-based, prospective cohort study. PARTICIPANTS: The cohort was a population-based random sample of citizens 50 years and older. Of 1379 eligible subjects, 1045 had a baseline examination in 1996; 846 of the 958 survivors (88.2%) had a 5-year follow-up examination in 2001. METHODS: The incidence of various characteristics of drusen and pigmentary changes that are typical of ARM were determined using the international classification and grading system for ARM and AMD. MAIN OUTCOME MEASURES: Early ARM and AMD were assessed by masked grading of stereo fundus photographs. RESULTS: Hypopigmentation developed at 5 years in 10.7% of people 50 to 59 years of age (95% confidence interval [CI], 6.9-14.4) and in 25.7% those 70 to 79 years of age (95% CI, 18.4-33.0) at baseline. Age-related macular degeneration developed in no one who was 50 to 59 years of age at baseline. Geographic atrophy (GA) developed in 4.6% (95% CI, 1.2-7.9) and exudative AMD in none of those who were 70 years and older at baseline. CONCLUSIONS: Geographic atrophy is the predominant type of AMD in Iceland, and the ratio of GA to neovascular AMD is higher than in racially similar populations. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Ophthalmology 112 1 132 138 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Research Support Non-U.S. Gov't Macular Degeneration Sex Distribution Age Distribution Aged 80 and over Middle Aged Iceland/epidemiology Male Female Population Surveillance Cohort Studies Prospective Studies |
spellingShingle |
Research Support Non-U.S. Gov't Macular Degeneration Sex Distribution Age Distribution Aged 80 and over Middle Aged Iceland/epidemiology Male Female Population Surveillance Cohort Studies Prospective Studies Jonasson, Fridbert Arnarsson, Arsaell Peto, Tunde Sasaki, Hiroshi Sasaki, Kazuyuki Bird, Alan C 5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
topic_facet |
Research Support Non-U.S. Gov't Macular Degeneration Sex Distribution Age Distribution Aged 80 and over Middle Aged Iceland/epidemiology Male Female Population Surveillance Cohort Studies Prospective Studies |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To examine the age- and gender-specific 5-year incidence of age-related maculopathy (ARM) and age-related macular degeneration (AMD) in citizens of Reykjavik. DESIGN: Population-based, prospective cohort study. PARTICIPANTS: The cohort was a population-based random sample of citizens 50 years and older. Of 1379 eligible subjects, 1045 had a baseline examination in 1996; 846 of the 958 survivors (88.2%) had a 5-year follow-up examination in 2001. METHODS: The incidence of various characteristics of drusen and pigmentary changes that are typical of ARM were determined using the international classification and grading system for ARM and AMD. MAIN OUTCOME MEASURES: Early ARM and AMD were assessed by masked grading of stereo fundus photographs. RESULTS: Hypopigmentation developed at 5 years in 10.7% of people 50 to 59 years of age (95% confidence interval [CI], 6.9-14.4) and in 25.7% those 70 to 79 years of age (95% CI, 18.4-33.0) at baseline. Age-related macular degeneration developed in no one who was 50 to 59 years of age at baseline. Geographic atrophy (GA) developed in 4.6% (95% CI, 1.2-7.9) and exudative AMD in none of those who were 70 years and older at baseline. CONCLUSIONS: Geographic atrophy is the predominant type of AMD in Iceland, and the ratio of GA to neovascular AMD is higher than in racially similar populations. |
format |
Article in Journal/Newspaper |
author |
Jonasson, Fridbert Arnarsson, Arsaell Peto, Tunde Sasaki, Hiroshi Sasaki, Kazuyuki Bird, Alan C |
author_facet |
Jonasson, Fridbert Arnarsson, Arsaell Peto, Tunde Sasaki, Hiroshi Sasaki, Kazuyuki Bird, Alan C |
author_sort |
Jonasson, Fridbert |
title |
5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
title_short |
5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
title_full |
5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
title_fullStr |
5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
title_full_unstemmed |
5-year incidence of age-related maculopathy in the Reykjavik Eye Study |
title_sort |
5-year incidence of age-related maculopathy in the reykjavik eye study |
publisher |
Elsevier |
publishDate |
2005 |
url |
http://hdl.handle.net/2336/2797 https://doi.org/10.1016/j.ophtha.2004.07.020 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.sciencedirect.com/science/article/B6VT2-4DW8TFM-C/2/6f7ffff017416492ebcbd8d6b92e78cb Ophthalmology 2005, 112(1):132-8 0161-6420 15629833 doi:10.1016/j.ophtha.2004.07.020 OPH12 http://hdl.handle.net/2336/2797 1549-4713 Ophthalmology |
op_doi |
https://doi.org/10.1016/j.ophtha.2004.07.020 |
container_title |
Ophthalmology |
container_volume |
112 |
container_issue |
1 |
container_start_page |
132 |
op_container_end_page |
138 |
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1766038817443151872 |