The association between birth size and atopy in young North-European adults
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results. METHODS: We wanted to inve...
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Online Access: | http://hdl.handle.net/2336/2776 https://doi.org/10.1111/j.1365-2222.2005.02289.x |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/2776 2023-05-15T16:51:12+02:00 The association between birth size and atopy in young North-European adults Laerum, B N Svanes, C Wentzel-Larsen, T Gulsvik, A Iversen, M Gislason, T Jögi, R Norrman, E Janson, C Omenaas, E 2005-08-01 YES http://hdl.handle.net/2336/2776 https://doi.org/10.1111/j.1365-2222.2005.02289.x en eng Blackwell Scientific Publications http://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2222.2005.02289.x Clin. Exp. Allergy 2005, 35(8):1022-7 0954-7894 16120083 doi:10.1111/j.1365-2222.2005.02289.x http://hdl.handle.net/2336/2776 Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Adult Age Distribution Birth Weight Denmark/epidemiology Eczema Estonia Female Head Humans Iceland/epidemiology Immunoglobulin E Male Middle Aged Norway/epidemiology Population Surveillance Prevalence Prospective Studies Respiratory Hypersensitivity Sex Distribution Sweden/epidemiology Article 2005 ftlandspitaliuni https://doi.org/10.1111/j.1365-2222.2005.02289.x 2022-05-29T08:20:50Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results. METHODS: We wanted to investigate the association of birth weight and head circumference with serum total or specific IgE, allergic rhinitis or eczema while addressing the influence of demographic and geographical factors. In this historic prospective cohort study, data were collected from birth records for 1683 men and women born in 1947-1973, from six Nordic-Baltic populations participating in the European Community Respiratory Health Survey. Blood tests for the measurement of serum total and specific IgE were available for 1494 subjects. In multiple regression analyses, adjustments were made for birth length, gender, age, study centre, adult body mass index, level of education, parental and adult smoking. RESULTS There was no association of birth weight (n=1230) and head circumference (n=285) with serum total IgE, specific IgE antibodies, allergic rhinitis or eczema. There were neither significant interactions by gender or age, nor heterogeneity between the study centres in the analyses of birth weight and adult atopy. CONCLUSION: Birth size was not associated with atopy among adults in this large Nordic-Baltic population study. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Norway Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy 35 8 1022 1027 |
institution |
Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adult Age Distribution Birth Weight Denmark/epidemiology Eczema Estonia Female Head Humans Iceland/epidemiology Immunoglobulin E Male Middle Aged Norway/epidemiology Population Surveillance Prevalence Prospective Studies Respiratory Hypersensitivity Sex Distribution Sweden/epidemiology |
spellingShingle |
Adult Age Distribution Birth Weight Denmark/epidemiology Eczema Estonia Female Head Humans Iceland/epidemiology Immunoglobulin E Male Middle Aged Norway/epidemiology Population Surveillance Prevalence Prospective Studies Respiratory Hypersensitivity Sex Distribution Sweden/epidemiology Laerum, B N Svanes, C Wentzel-Larsen, T Gulsvik, A Iversen, M Gislason, T Jögi, R Norrman, E Janson, C Omenaas, E The association between birth size and atopy in young North-European adults |
topic_facet |
Adult Age Distribution Birth Weight Denmark/epidemiology Eczema Estonia Female Head Humans Iceland/epidemiology Immunoglobulin E Male Middle Aged Norway/epidemiology Population Surveillance Prevalence Prospective Studies Respiratory Hypersensitivity Sex Distribution Sweden/epidemiology |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: There is evidence that atopic disorders may begin in intra-uterine life; however, studies of birth characteristics and atopy show conflicting results. METHODS: We wanted to investigate the association of birth weight and head circumference with serum total or specific IgE, allergic rhinitis or eczema while addressing the influence of demographic and geographical factors. In this historic prospective cohort study, data were collected from birth records for 1683 men and women born in 1947-1973, from six Nordic-Baltic populations participating in the European Community Respiratory Health Survey. Blood tests for the measurement of serum total and specific IgE were available for 1494 subjects. In multiple regression analyses, adjustments were made for birth length, gender, age, study centre, adult body mass index, level of education, parental and adult smoking. RESULTS There was no association of birth weight (n=1230) and head circumference (n=285) with serum total IgE, specific IgE antibodies, allergic rhinitis or eczema. There were neither significant interactions by gender or age, nor heterogeneity between the study centres in the analyses of birth weight and adult atopy. CONCLUSION: Birth size was not associated with atopy among adults in this large Nordic-Baltic population study. |
format |
Article in Journal/Newspaper |
author |
Laerum, B N Svanes, C Wentzel-Larsen, T Gulsvik, A Iversen, M Gislason, T Jögi, R Norrman, E Janson, C Omenaas, E |
author_facet |
Laerum, B N Svanes, C Wentzel-Larsen, T Gulsvik, A Iversen, M Gislason, T Jögi, R Norrman, E Janson, C Omenaas, E |
author_sort |
Laerum, B N |
title |
The association between birth size and atopy in young North-European adults |
title_short |
The association between birth size and atopy in young North-European adults |
title_full |
The association between birth size and atopy in young North-European adults |
title_fullStr |
The association between birth size and atopy in young North-European adults |
title_full_unstemmed |
The association between birth size and atopy in young North-European adults |
title_sort |
association between birth size and atopy in young north-european adults |
publisher |
Blackwell Scientific Publications |
publishDate |
2005 |
url |
http://hdl.handle.net/2336/2776 https://doi.org/10.1111/j.1365-2222.2005.02289.x |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2222.2005.02289.x Clin. Exp. Allergy 2005, 35(8):1022-7 0954-7894 16120083 doi:10.1111/j.1365-2222.2005.02289.x http://hdl.handle.net/2336/2776 Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology |
op_doi |
https://doi.org/10.1111/j.1365-2222.2005.02289.x |
container_title |
Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy |
container_volume |
35 |
container_issue |
8 |
container_start_page |
1022 |
op_container_end_page |
1027 |
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1766041306509869056 |