Beinþéttni ungra kvenna með sögu um lystarstol
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text OBJECTIVE: A decrease in bone mineral density (BMD) is frequently seen in patients with anorexia nervosa (AN). This study was designed to assess BMD of young Icelandic women with...
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | Icelandic |
Published: |
Læknafélag Íslands, Læknafélag Reykjavíkur
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/255254 |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/255254 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/255254 2023-05-15T16:50:01+02:00 Beinþéttni ungra kvenna með sögu um lystarstol Bone mineral density of young women with history of anorexia nervosa Rebekka Guðrún Rúnarsdóttir Guðlaug Þorsteinsdóttir Ólafur Skúli Indriðason Gunnar Sigurðsson Landspitali The National University Hospital, Reykjavík, Iceland. Faculty of Medicine, University of Iceland, Iceland. 2012-12-11 http://hdl.handle.net/2336/255254 ice is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is Læknablaðið 2012, 98(10):523-9 0023-7213 23043065 http://hdl.handle.net/2336/255254 Læknablaðið Archived with thanks to Læknablađiđ Open Access - Opinn aðgangur Anorexía Lystarstol Líkamasþyngd Beinþynning Konur Absorptiometry Photon Adolescent Adult Age Factors Anorexia Nervosa Body Mass Index Bone Density Bone Diseases Bone Remodeling Bone and Bones Female Femur Neck Hip Joint Humans Iceland Lumbar Vertebrae Retrospective Studies Sex Factors Young Adult Article Innkirtlalæknisfræði, Geðlækningar, Nýrnalæknisfræði 2012 ftlandspitaliuni 2022-05-29T08:21:49Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text OBJECTIVE: A decrease in bone mineral density (BMD) is frequently seen in patients with anorexia nervosa (AN). This study was designed to assess BMD of young Icelandic women with current or previous history of AN and identify predictors which might be targets for preventive measures. MATERIAL AND METHODS: The study was retrospective. Participants were women aged 18-40 years, with diagnosis of AN (F50.0, F50.1) attending the anorexia unit at Landspítali - The National University Hospital of Iceland - in 2001-2009, who had undergone measurement of BMD by dual-energy X-ray absorptiometry. A control group consisted of 58 healthy 30 years old women participating in a study of bone health in 2001-2003. RESULTS: At time of BMD measurement the median body mass index (BMI: kg/m2) in the AN group (n=40) was 17.4 (12.3-25.2) compared to 23.6 (18.1-43.7) in the control group (p<0,001). Lumbar spine and hip BMD were 15.3-17.5% lower in AN patients than in control subjects (p<0.001). In both groups there was a strong correlation between BMD and body weight (r=0.354-0.604, p<0.05) and lean mass (r=0.425-0.588, p<0.05). Among patients with AN a correlation was also seen between BMD and lowest weight during the illness (r=0.482-0.499, p<0.01). Among the 26 AN patients who had repeated BMD measurement, a significant decrease in BMD at femoral neck (-6.6%, p=0.030) was observed in those who lost weight between the measurements (n=9). Those who had BMI ≤17.5 between BMD measurements lost 5.5-7.1% of the BMD at the hip (p<0.05). CONCLUSION: Young women with AN have 15% lower bone mass than healthy young women. The relationship between BMD and body weight seems to be a continuum across disease states. Increased body weight may be the most important factor for recovery of bone mass in AN patients. Tilgangur: Lág beinþéttni er algeng hjá sjúklingum með lystarstol en það vantar rannsóknir ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Kvenna ENVELOPE(18.430,18.430,69.216,69.216) Smella ENVELOPE(29.443,29.443,69.896,69.896) |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Anorexía Lystarstol Líkamasþyngd Beinþynning Konur Absorptiometry Photon Adolescent Adult Age Factors Anorexia Nervosa Body Mass Index Bone Density Bone Diseases Bone Remodeling Bone and Bones Female Femur Neck Hip Joint Humans Iceland Lumbar Vertebrae Retrospective Studies Sex Factors Young Adult |
spellingShingle |
Anorexía Lystarstol Líkamasþyngd Beinþynning Konur Absorptiometry Photon Adolescent Adult Age Factors Anorexia Nervosa Body Mass Index Bone Density Bone Diseases Bone Remodeling Bone and Bones Female Femur Neck Hip Joint Humans Iceland Lumbar Vertebrae Retrospective Studies Sex Factors Young Adult Rebekka Guðrún Rúnarsdóttir Guðlaug Þorsteinsdóttir Ólafur Skúli Indriðason Gunnar Sigurðsson Beinþéttni ungra kvenna með sögu um lystarstol |
topic_facet |
Anorexía Lystarstol Líkamasþyngd Beinþynning Konur Absorptiometry Photon Adolescent Adult Age Factors Anorexia Nervosa Body Mass Index Bone Density Bone Diseases Bone Remodeling Bone and Bones Female Femur Neck Hip Joint Humans Iceland Lumbar Vertebrae Retrospective Studies Sex Factors Young Adult |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text OBJECTIVE: A decrease in bone mineral density (BMD) is frequently seen in patients with anorexia nervosa (AN). This study was designed to assess BMD of young Icelandic women with current or previous history of AN and identify predictors which might be targets for preventive measures. MATERIAL AND METHODS: The study was retrospective. Participants were women aged 18-40 years, with diagnosis of AN (F50.0, F50.1) attending the anorexia unit at Landspítali - The National University Hospital of Iceland - in 2001-2009, who had undergone measurement of BMD by dual-energy X-ray absorptiometry. A control group consisted of 58 healthy 30 years old women participating in a study of bone health in 2001-2003. RESULTS: At time of BMD measurement the median body mass index (BMI: kg/m2) in the AN group (n=40) was 17.4 (12.3-25.2) compared to 23.6 (18.1-43.7) in the control group (p<0,001). Lumbar spine and hip BMD were 15.3-17.5% lower in AN patients than in control subjects (p<0.001). In both groups there was a strong correlation between BMD and body weight (r=0.354-0.604, p<0.05) and lean mass (r=0.425-0.588, p<0.05). Among patients with AN a correlation was also seen between BMD and lowest weight during the illness (r=0.482-0.499, p<0.01). Among the 26 AN patients who had repeated BMD measurement, a significant decrease in BMD at femoral neck (-6.6%, p=0.030) was observed in those who lost weight between the measurements (n=9). Those who had BMI ≤17.5 between BMD measurements lost 5.5-7.1% of the BMD at the hip (p<0.05). CONCLUSION: Young women with AN have 15% lower bone mass than healthy young women. The relationship between BMD and body weight seems to be a continuum across disease states. Increased body weight may be the most important factor for recovery of bone mass in AN patients. Tilgangur: Lág beinþéttni er algeng hjá sjúklingum með lystarstol en það vantar rannsóknir ... |
author2 |
Landspitali The National University Hospital, Reykjavík, Iceland. Faculty of Medicine, University of Iceland, Iceland. |
format |
Article in Journal/Newspaper |
author |
Rebekka Guðrún Rúnarsdóttir Guðlaug Þorsteinsdóttir Ólafur Skúli Indriðason Gunnar Sigurðsson |
author_facet |
Rebekka Guðrún Rúnarsdóttir Guðlaug Þorsteinsdóttir Ólafur Skúli Indriðason Gunnar Sigurðsson |
author_sort |
Rebekka Guðrún Rúnarsdóttir |
title |
Beinþéttni ungra kvenna með sögu um lystarstol |
title_short |
Beinþéttni ungra kvenna með sögu um lystarstol |
title_full |
Beinþéttni ungra kvenna með sögu um lystarstol |
title_fullStr |
Beinþéttni ungra kvenna með sögu um lystarstol |
title_full_unstemmed |
Beinþéttni ungra kvenna með sögu um lystarstol |
title_sort |
beinþéttni ungra kvenna með sögu um lystarstol |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2012 |
url |
http://hdl.handle.net/2336/255254 |
long_lat |
ENVELOPE(18.430,18.430,69.216,69.216) ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Kvenna Smella |
geographic_facet |
Kvenna Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is Læknablaðið 2012, 98(10):523-9 0023-7213 23043065 http://hdl.handle.net/2336/255254 Læknablaðið |
op_rights |
Archived with thanks to Læknablađiđ Open Access - Opinn aðgangur |
_version_ |
1766040198202785792 |