Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text BACKGROUND AND AIMS: Transarterial chemoembolization (TACE) is a loco-regional therapy performed to treat tumors in the liver. The branch of the hepatic artery supplying the tumor...
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Læknafélag Íslands, Læknafélag Reykjavíkur
2013
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Online Access: | http://hdl.handle.net/2336/238253 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/238253 2023-05-15T16:48:03+02:00 Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi Loco-regional therapy for liver malignancy in Iceland Þórarinn Árni Bjarnason Haraldur Bjarnason Óttar Már Bergmann Hjalti Már Þórisson Landspitali The National University Hospital, University of Iceland, Reykjavik, Iceland 2013-08-13 http://hdl.handle.net/2336/238253 ice is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www. laeknabladid.is Læknablaðið 2012, 98(6):334-40 0023-7213 22647444 http://hdl.handle.net/2336/238253 Læknablaðið Archived with thanks to Læknablađiđ Open Access - Opinn aðgangur Krabbameinslækningar Krabbamein Lifrarsjúkdómar Aged 80 and over Carcinoma Hepatocellular Catheter Ablation Chemoembolization Therapeutic Chemotherapy Adjuvant Female Hepatectomy Hepatic Artery Humans Iceland Liver Neoplasms Liver Transplantation Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Palliative Care Radiography Interventional Survival Analysis Time Factors Treatment Outcome Article Röntgen, meltingarfr 2013 ftlandspitaliuni 2022-05-29T08:21:49Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text BACKGROUND AND AIMS: Transarterial chemoembolization (TACE) is a loco-regional therapy performed to treat tumors in the liver. The branch of the hepatic artery supplying the tumor is catheterized and a mixture of iodized oil, chemotherapeutic agents and PVA embolic materials infused. TACE is a palliative treatment of unresectable cancer in the liver but can also be employed as adjunctive therapy to liver resection and/or radiofrequency ablation. The procedure can in certain instances downstage the disease and provide a bridge to liver transplantation. The aim of this study was to evaluate outcome in patients that have undergone loco-regional therapy in Iceland and the frequency and severity of complications related to the procedure. MATERIAL AND METHODS: All Icelandic patients that had undergone TACE, transarterial chemotherapy or bland embolization of liver tumors between 1 May 2007 and 1 March 2011 were included in the study. RESULTS: Eighteen TACE, six transarterial chemotherapy treatments and two bland embolizations were performed on nine patients with hepatocellular carcinoma (HCC), and three patients with carcinoid metastases in the liver. Mean-survival of patients with HCC was 15.2 months. Survival of patients with carcinoid metastases was between 61 and 180 months. Complete response was achieved twice and partial response four times. The disease remained stable after eleven procedures but progressed after three procedures. Minor complications were diagnosed in 6 of 26 procedures and one major complication. No patient suffered from liver failure due to the procedure. Of the 9 HCC patients, 1 patient was on the liver transplant list before TACE and later underwent successful transplantation. Additionally, 3 of the remaining 8 patients were downstaged and put on to the transplant list. Inngangur: Innæðakrabbameinslyfjameðferð með slagæðastíflun er staðbundin krabbameinsmeðferð til að ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Smella ENVELOPE(29.443,29.443,69.896,69.896) |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Krabbameinslækningar Krabbamein Lifrarsjúkdómar Aged 80 and over Carcinoma Hepatocellular Catheter Ablation Chemoembolization Therapeutic Chemotherapy Adjuvant Female Hepatectomy Hepatic Artery Humans Iceland Liver Neoplasms Liver Transplantation Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Palliative Care Radiography Interventional Survival Analysis Time Factors Treatment Outcome |
spellingShingle |
Krabbameinslækningar Krabbamein Lifrarsjúkdómar Aged 80 and over Carcinoma Hepatocellular Catheter Ablation Chemoembolization Therapeutic Chemotherapy Adjuvant Female Hepatectomy Hepatic Artery Humans Iceland Liver Neoplasms Liver Transplantation Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Palliative Care Radiography Interventional Survival Analysis Time Factors Treatment Outcome Þórarinn Árni Bjarnason Haraldur Bjarnason Óttar Már Bergmann Hjalti Már Þórisson Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
topic_facet |
Krabbameinslækningar Krabbamein Lifrarsjúkdómar Aged 80 and over Carcinoma Hepatocellular Catheter Ablation Chemoembolization Therapeutic Chemotherapy Adjuvant Female Hepatectomy Hepatic Artery Humans Iceland Liver Neoplasms Liver Transplantation Male Middle Aged Neoadjuvant Therapy Neoplasm Staging Palliative Care Radiography Interventional Survival Analysis Time Factors Treatment Outcome |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Allur texti - Full text BACKGROUND AND AIMS: Transarterial chemoembolization (TACE) is a loco-regional therapy performed to treat tumors in the liver. The branch of the hepatic artery supplying the tumor is catheterized and a mixture of iodized oil, chemotherapeutic agents and PVA embolic materials infused. TACE is a palliative treatment of unresectable cancer in the liver but can also be employed as adjunctive therapy to liver resection and/or radiofrequency ablation. The procedure can in certain instances downstage the disease and provide a bridge to liver transplantation. The aim of this study was to evaluate outcome in patients that have undergone loco-regional therapy in Iceland and the frequency and severity of complications related to the procedure. MATERIAL AND METHODS: All Icelandic patients that had undergone TACE, transarterial chemotherapy or bland embolization of liver tumors between 1 May 2007 and 1 March 2011 were included in the study. RESULTS: Eighteen TACE, six transarterial chemotherapy treatments and two bland embolizations were performed on nine patients with hepatocellular carcinoma (HCC), and three patients with carcinoid metastases in the liver. Mean-survival of patients with HCC was 15.2 months. Survival of patients with carcinoid metastases was between 61 and 180 months. Complete response was achieved twice and partial response four times. The disease remained stable after eleven procedures but progressed after three procedures. Minor complications were diagnosed in 6 of 26 procedures and one major complication. No patient suffered from liver failure due to the procedure. Of the 9 HCC patients, 1 patient was on the liver transplant list before TACE and later underwent successful transplantation. Additionally, 3 of the remaining 8 patients were downstaged and put on to the transplant list. Inngangur: Innæðakrabbameinslyfjameðferð með slagæðastíflun er staðbundin krabbameinsmeðferð til að ... |
author2 |
Landspitali The National University Hospital, University of Iceland, Reykjavik, Iceland |
format |
Article in Journal/Newspaper |
author |
Þórarinn Árni Bjarnason Haraldur Bjarnason Óttar Már Bergmann Hjalti Már Þórisson |
author_facet |
Þórarinn Árni Bjarnason Haraldur Bjarnason Óttar Már Bergmann Hjalti Már Þórisson |
author_sort |
Þórarinn Árni Bjarnason |
title |
Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
title_short |
Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
title_full |
Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
title_fullStr |
Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
title_full_unstemmed |
Innæða krabbameinslyfjameðferð með slagæðastíflun: Árangur staðbundinnar krabbameinsmeðferðar á Íslandi |
title_sort |
innæða krabbameinslyfjameðferð með slagæðastíflun: árangur staðbundinnar krabbameinsmeðferðar á íslandi |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2013 |
url |
http://hdl.handle.net/2336/238253 |
long_lat |
ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Smella |
geographic_facet |
Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www. laeknabladid.is Læknablaðið 2012, 98(6):334-40 0023-7213 22647444 http://hdl.handle.net/2336/238253 Læknablaðið |
op_rights |
Archived with thanks to Læknablađiđ Open Access - Opinn aðgangur |
_version_ |
1766038153202761728 |