Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup.
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. OBJECTIVE: To evaluate the association between radiographic hip osteoarthritis (OA) and future total hip replacement (THR) due to OA or hip fracture. METHODS: We studied a cohort of indivi...
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/223612 2023-05-15T16:52:47+02:00 Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. Franklin, Jonas Ingvarsson, Thorvaldur Englund, Martin Ingimarsson, Olafur Robertsson, Otto Lohmander, L Stefan Landspitali The National University Hospital, Reykjavík, Iceland. University Hospital, Akureyri, Iceland. 2012-05-14 http://hdl.handle.net/2336/223612 https://doi.org/10.1002/acr.20412 en eng John Wiley & Sons http://dx.doi.org/10.1002/acr.20412 Arthritis. Care. Res. (Hoboken). 2011, 63 (5):689-95 2151-4658 21557524 doi:10.1002/acr.20412 http://hdl.handle.net/2336/223612 Arthritis care & research Archived with thanks to Arthritis care & research Adult Aged 80 and over Arthroplasty Replacement Hip Disease Progression Female Follow-Up Studies Hip Fractures Hip Joint Humans Iceland Male Middle Aged Osteoarthritis Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Assessment Risk Factors Severity of Illness Index Time Factors Article 2012 ftlandspitaliuni https://doi.org/10.1002/acr.20412 2022-05-29T08:21:46Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. OBJECTIVE: To evaluate the association between radiographic hip osteoarthritis (OA) and future total hip replacement (THR) due to OA or hip fracture. METHODS: We studied a cohort of individuals who had colon radiography from 1980-1997. Minimal joint space (MJS) was measured and each hip was graded for radiographic OA according to the Kellgren/Lawrence scale. Subjects were followed until the end of 2008. A Cox proportional hazards model, adjusted for age and sex, was used to evaluate factors associated with THR and hip fracture. RESULTS: A total of 2,953 hips were studied (57% women). The cumulative incidence of THR was 2.5% and the cumulative incidence of hip fracture was 2.6%. For hips with radiographic hip OA (MJS of 2.5 mm or less), the cumulative incidence of THR was 16.9% and the hazard ratio (HR) for THR was 13.2 (95% confidence interval [95% CI] 8.1-21). Using Kellgren/Lawrence grading, the HR for THR was 12.9 (95% CI 7.9-21) for hips with radiographic OA compared to those without. The HR for all types of hip fracture for hips with radiographic OA (MJS of 2.5 mm or less) was 0.47 (95% CI 0.15-1.5), for intracapsular fractures was 0.29 (95% CI 0.04-2.1), and for extracapsular fractures was 0.67 (95% CI 0.16-2.8). CONCLUSION: The risk of THR due to OA is substantially increased in patients with radiographic hip OA, regardless of symptoms, and increases with decreasing MJS. However, 11-28 years after having had radiographic hip OA, more than 4 of 5 of those having radiographic signs of hip OA had not had a THR for OA. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Arthritis Care & Research 63 5 689 695 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adult Aged 80 and over Arthroplasty Replacement Hip Disease Progression Female Follow-Up Studies Hip Fractures Hip Joint Humans Iceland Male Middle Aged Osteoarthritis Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Assessment Risk Factors Severity of Illness Index Time Factors |
spellingShingle |
Adult Aged 80 and over Arthroplasty Replacement Hip Disease Progression Female Follow-Up Studies Hip Fractures Hip Joint Humans Iceland Male Middle Aged Osteoarthritis Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Assessment Risk Factors Severity of Illness Index Time Factors Franklin, Jonas Ingvarsson, Thorvaldur Englund, Martin Ingimarsson, Olafur Robertsson, Otto Lohmander, L Stefan Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
topic_facet |
Adult Aged 80 and over Arthroplasty Replacement Hip Disease Progression Female Follow-Up Studies Hip Fractures Hip Joint Humans Iceland Male Middle Aged Osteoarthritis Predictive Value of Tests Proportional Hazards Models Retrospective Studies Risk Assessment Risk Factors Severity of Illness Index Time Factors |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field. OBJECTIVE: To evaluate the association between radiographic hip osteoarthritis (OA) and future total hip replacement (THR) due to OA or hip fracture. METHODS: We studied a cohort of individuals who had colon radiography from 1980-1997. Minimal joint space (MJS) was measured and each hip was graded for radiographic OA according to the Kellgren/Lawrence scale. Subjects were followed until the end of 2008. A Cox proportional hazards model, adjusted for age and sex, was used to evaluate factors associated with THR and hip fracture. RESULTS: A total of 2,953 hips were studied (57% women). The cumulative incidence of THR was 2.5% and the cumulative incidence of hip fracture was 2.6%. For hips with radiographic hip OA (MJS of 2.5 mm or less), the cumulative incidence of THR was 16.9% and the hazard ratio (HR) for THR was 13.2 (95% confidence interval [95% CI] 8.1-21). Using Kellgren/Lawrence grading, the HR for THR was 12.9 (95% CI 7.9-21) for hips with radiographic OA compared to those without. The HR for all types of hip fracture for hips with radiographic OA (MJS of 2.5 mm or less) was 0.47 (95% CI 0.15-1.5), for intracapsular fractures was 0.29 (95% CI 0.04-2.1), and for extracapsular fractures was 0.67 (95% CI 0.16-2.8). CONCLUSION: The risk of THR due to OA is substantially increased in patients with radiographic hip OA, regardless of symptoms, and increases with decreasing MJS. However, 11-28 years after having had radiographic hip OA, more than 4 of 5 of those having radiographic signs of hip OA had not had a THR for OA. |
author2 |
Landspitali The National University Hospital, Reykjavík, Iceland. University Hospital, Akureyri, Iceland. |
format |
Article in Journal/Newspaper |
author |
Franklin, Jonas Ingvarsson, Thorvaldur Englund, Martin Ingimarsson, Olafur Robertsson, Otto Lohmander, L Stefan |
author_facet |
Franklin, Jonas Ingvarsson, Thorvaldur Englund, Martin Ingimarsson, Olafur Robertsson, Otto Lohmander, L Stefan |
author_sort |
Franklin, Jonas |
title |
Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
title_short |
Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
title_full |
Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
title_fullStr |
Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
title_full_unstemmed |
Natural history of radiographic hip osteoarthritis: A retrospective cohort study with 11-28 years of followup. |
title_sort |
natural history of radiographic hip osteoarthritis: a retrospective cohort study with 11-28 years of followup. |
publisher |
John Wiley & Sons |
publishDate |
2012 |
url |
http://hdl.handle.net/2336/223612 https://doi.org/10.1002/acr.20412 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1002/acr.20412 Arthritis. Care. Res. (Hoboken). 2011, 63 (5):689-95 2151-4658 21557524 doi:10.1002/acr.20412 http://hdl.handle.net/2336/223612 Arthritis care & research |
op_rights |
Archived with thanks to Arthritis care & research |
op_doi |
https://doi.org/10.1002/acr.20412 |
container_title |
Arthritis Care & Research |
container_volume |
63 |
container_issue |
5 |
container_start_page |
689 |
op_container_end_page |
695 |
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1766043184918429696 |