A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries.
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Eight haematological quantities were measured in EDTA anticoagulated venous blood specimens collected from 1826 healthy male and female individuals between 18 and 90 years of age in the Nor...
Published in: | Scandinavian Journal of Clinical and Laboratory Investigation |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Taylor & Francis Health Sciences
2008
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/21872 https://doi.org/10.1080/00365510410002797 |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/21872 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/21872 2023-05-15T16:52:47+02:00 A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. Nordin, G Mårtensson, A Swolin, B Sandberg, S Christensen, N J Thorsteinsson, V Franzson, L Kairisto, V Savolainen, E-R 2008-03-28 http://hdl.handle.net/2336/21872 https://doi.org/10.1080/00365510410002797 en eng Taylor & Francis Health Sciences http://www.informaworld.com/10.1080/00365510410002797 Scand. J. Clin. Lab. Invest. 2004, 64(4):385-98 0036-5513 15223702 doi:10.1080/00365510410002797 http://hdl.handle.net/2336/21872 Scandinavian journal of clinical and laboratory investigation Adolescent Adult Aged 80 and over Chemistry Clinical Clinical Medicine Europe Female Hematologic Tests Humans International Cooperation Laboratories Hospital Male Middle Aged Reference Values Article 2008 ftlandspitaliuni https://doi.org/10.1080/00365510410002797 2022-05-29T08:21:07Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Eight haematological quantities were measured in EDTA anticoagulated venous blood specimens collected from 1826 healthy male and female individuals between 18 and 90 years of age in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden). The samples, collected between November 1999 and November 2001 as part of the Nordic Reference Interval Project (NORIP), were analysed on 12 different types of modern automated haematology instruments currently in use among the 60 laboratories participating in the study. Non-parametric reference intervals (between 2.5 and 97.5 percentiles) have been calculated for B-Haemoglobin (females 117-153 g/L, males 134-170 g/L), B-Erythrocytes (females 3.94-5.16 x 10(12)/L, males 4.25-5.71 x 10(12)/L), B-EVF (females 0.348-0.459, males 0.395-0.500), B-MCV (82-98 fL), Erc-MCH (27.1-33.3 pg), Erc-MCHC (317-357 g/L), B-Trc (females 165-387 x 10(9)/L, males 145 x 348 x 10(9)/L) and B-Lkc (3.5-8.8 x 10(9)/L). Partitioning of data according to age and gender was done according to a standardized procedure. For most variables the calculated reference intervals corresponded well with older and less well-defined reference intervals. The mean concentration of B-Haemoglobin increased by 0.08 g/L per year of age in women, and decreased by 0.1 g/L per year of age in men. B-Haemoglobin increased with body mass index in both men and women. Smoking increased the mean of B-Lkc by 1.1 x 10(9)/L and regular use of alcohol increased the mean of B-MCV by 0.8 fL. The influence of these factors was small overall and did not promote specific reference intervals. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Norway Scandinavian Journal of Clinical and Laboratory Investigation 64 4 385 398 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adolescent Adult Aged 80 and over Chemistry Clinical Clinical Medicine Europe Female Hematologic Tests Humans International Cooperation Laboratories Hospital Male Middle Aged Reference Values |
spellingShingle |
Adolescent Adult Aged 80 and over Chemistry Clinical Clinical Medicine Europe Female Hematologic Tests Humans International Cooperation Laboratories Hospital Male Middle Aged Reference Values Nordin, G Mårtensson, A Swolin, B Sandberg, S Christensen, N J Thorsteinsson, V Franzson, L Kairisto, V Savolainen, E-R A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
topic_facet |
Adolescent Adult Aged 80 and over Chemistry Clinical Clinical Medicine Europe Female Hematologic Tests Humans International Cooperation Laboratories Hospital Male Middle Aged Reference Values |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field Eight haematological quantities were measured in EDTA anticoagulated venous blood specimens collected from 1826 healthy male and female individuals between 18 and 90 years of age in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden). The samples, collected between November 1999 and November 2001 as part of the Nordic Reference Interval Project (NORIP), were analysed on 12 different types of modern automated haematology instruments currently in use among the 60 laboratories participating in the study. Non-parametric reference intervals (between 2.5 and 97.5 percentiles) have been calculated for B-Haemoglobin (females 117-153 g/L, males 134-170 g/L), B-Erythrocytes (females 3.94-5.16 x 10(12)/L, males 4.25-5.71 x 10(12)/L), B-EVF (females 0.348-0.459, males 0.395-0.500), B-MCV (82-98 fL), Erc-MCH (27.1-33.3 pg), Erc-MCHC (317-357 g/L), B-Trc (females 165-387 x 10(9)/L, males 145 x 348 x 10(9)/L) and B-Lkc (3.5-8.8 x 10(9)/L). Partitioning of data according to age and gender was done according to a standardized procedure. For most variables the calculated reference intervals corresponded well with older and less well-defined reference intervals. The mean concentration of B-Haemoglobin increased by 0.08 g/L per year of age in women, and decreased by 0.1 g/L per year of age in men. B-Haemoglobin increased with body mass index in both men and women. Smoking increased the mean of B-Lkc by 1.1 x 10(9)/L and regular use of alcohol increased the mean of B-MCV by 0.8 fL. The influence of these factors was small overall and did not promote specific reference intervals. |
format |
Article in Journal/Newspaper |
author |
Nordin, G Mårtensson, A Swolin, B Sandberg, S Christensen, N J Thorsteinsson, V Franzson, L Kairisto, V Savolainen, E-R |
author_facet |
Nordin, G Mårtensson, A Swolin, B Sandberg, S Christensen, N J Thorsteinsson, V Franzson, L Kairisto, V Savolainen, E-R |
author_sort |
Nordin, G |
title |
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
title_short |
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
title_full |
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
title_fullStr |
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
title_full_unstemmed |
A multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the Nordic countries. |
title_sort |
multicentre study of reference intervals for haemoglobin, basic blood cell counts and erythrocyte indices in the adult population of the nordic countries. |
publisher |
Taylor & Francis Health Sciences |
publishDate |
2008 |
url |
http://hdl.handle.net/2336/21872 https://doi.org/10.1080/00365510410002797 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.informaworld.com/10.1080/00365510410002797 Scand. J. Clin. Lab. Invest. 2004, 64(4):385-98 0036-5513 15223702 doi:10.1080/00365510410002797 http://hdl.handle.net/2336/21872 Scandinavian journal of clinical and laboratory investigation |
op_doi |
https://doi.org/10.1080/00365510410002797 |
container_title |
Scandinavian Journal of Clinical and Laboratory Investigation |
container_volume |
64 |
container_issue |
4 |
container_start_page |
385 |
op_container_end_page |
398 |
_version_ |
1766043167132483584 |