Lifrarfrumukrabbamein á Íslandi
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Introduction: The incidence of hepatocellular carcinoma (HCC) varies throughout the world, being relatively low in Northern Europe (less than five per 100,000 population) where the majority of the patien...
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Læknafélag Íslands, Læknafélag Reykjavíkur
2008
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/20856 2023-05-15T16:45:07+02:00 Lifrarfrumukrabbamein á Íslandi Hepatocellular carcinoma in Iceland Brynja Ragnarsdóttir Jón Gunnlaugur Jónasson Hrafn Tulinius Sigurður Ólafsson Department of Medicine, Landspitali University Hospital, Fossvogi, 108 Reykjavík, Iceland. sigurdol@landspitali.is. 2008-03-17 http://hdl.handle.net/2336/20856 ICE is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is Læknablaðið 2001, 87(6):527-31 0023-7213 17018993 http://hdl.handle.net/2336/20856 Læknablaðið Krabbamein Faraldsfræði Lifrarbólga LBL12 Carcinoma Hepatocellular Iceland Epidemiology Hepatitis C Article 2008 ftlandspitaliuni 2022-05-29T08:21:07Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Introduction: The incidence of hepatocellular carcinoma (HCC) varies throughout the world, being relatively low in Northern Europe (less than five per 100,000 population) where the majority of the patients have cirrhosis. In Iceland the prevalence of viral hepatitis and cirrhosis, the main risk factors for HCC, is lower than reported in many other countries. The aim of our study was to investigate the incidence and etiology of HCC in Iceland. Material and methods: All patients diagnosed with HCC in Iceland in 1984-1998 were included in the study. Histologic diagnosis was required for inclusion. Patients were identified from the Icelandic Cancer Registry and by reviewing autopsy and histopathology reports. Further information was obtained from medical records. Results: A total of 71 cases of HCC were identified, 51 males and 20 females. The mean age for males was 69.3 years (18-95) and 73 years (52-89) for females. The age-standardized annual incidence rate of HCC was 1.08/100,000 (males 2.10, females 0.67). The incidence did not increase significantly during the study period. Alcohol abuse (15.5%) and hemochromatosis (11%) were the most common risk factors. Twenty-three (32%) had cirrhosis but 39 (55%) had no known risk factors. Of 55 cases where non-neoplastic tissue was available for examination, 27 had liver disease. Conclusions: 1) The incidence of HCC in Iceland is lower than reported in other countries. 2) Alcohol abuse and hemochromatosis are the most common risk factors. 3) The ratio of patients with cirrhosis is low. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Smella ENVELOPE(29.443,29.443,69.896,69.896) |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Krabbamein Faraldsfræði Lifrarbólga LBL12 Carcinoma Hepatocellular Iceland Epidemiology Hepatitis C |
spellingShingle |
Krabbamein Faraldsfræði Lifrarbólga LBL12 Carcinoma Hepatocellular Iceland Epidemiology Hepatitis C Brynja Ragnarsdóttir Jón Gunnlaugur Jónasson Hrafn Tulinius Sigurður Ólafsson Lifrarfrumukrabbamein á Íslandi |
topic_facet |
Krabbamein Faraldsfræði Lifrarbólga LBL12 Carcinoma Hepatocellular Iceland Epidemiology Hepatitis C |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Introduction: The incidence of hepatocellular carcinoma (HCC) varies throughout the world, being relatively low in Northern Europe (less than five per 100,000 population) where the majority of the patients have cirrhosis. In Iceland the prevalence of viral hepatitis and cirrhosis, the main risk factors for HCC, is lower than reported in many other countries. The aim of our study was to investigate the incidence and etiology of HCC in Iceland. Material and methods: All patients diagnosed with HCC in Iceland in 1984-1998 were included in the study. Histologic diagnosis was required for inclusion. Patients were identified from the Icelandic Cancer Registry and by reviewing autopsy and histopathology reports. Further information was obtained from medical records. Results: A total of 71 cases of HCC were identified, 51 males and 20 females. The mean age for males was 69.3 years (18-95) and 73 years (52-89) for females. The age-standardized annual incidence rate of HCC was 1.08/100,000 (males 2.10, females 0.67). The incidence did not increase significantly during the study period. Alcohol abuse (15.5%) and hemochromatosis (11%) were the most common risk factors. Twenty-three (32%) had cirrhosis but 39 (55%) had no known risk factors. Of 55 cases where non-neoplastic tissue was available for examination, 27 had liver disease. Conclusions: 1) The incidence of HCC in Iceland is lower than reported in other countries. 2) Alcohol abuse and hemochromatosis are the most common risk factors. 3) The ratio of patients with cirrhosis is low. |
author2 |
Department of Medicine, Landspitali University Hospital, Fossvogi, 108 Reykjavík, Iceland. sigurdol@landspitali.is. |
format |
Article in Journal/Newspaper |
author |
Brynja Ragnarsdóttir Jón Gunnlaugur Jónasson Hrafn Tulinius Sigurður Ólafsson |
author_facet |
Brynja Ragnarsdóttir Jón Gunnlaugur Jónasson Hrafn Tulinius Sigurður Ólafsson |
author_sort |
Brynja Ragnarsdóttir |
title |
Lifrarfrumukrabbamein á Íslandi |
title_short |
Lifrarfrumukrabbamein á Íslandi |
title_full |
Lifrarfrumukrabbamein á Íslandi |
title_fullStr |
Lifrarfrumukrabbamein á Íslandi |
title_full_unstemmed |
Lifrarfrumukrabbamein á Íslandi |
title_sort |
lifrarfrumukrabbamein á íslandi |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2008 |
url |
http://hdl.handle.net/2336/20856 |
long_lat |
ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Smella |
geographic_facet |
Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is Læknablaðið 2001, 87(6):527-31 0023-7213 17018993 http://hdl.handle.net/2336/20856 Læknablaðið |
_version_ |
1766035323270201344 |