Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn
Adenocarcinoma of the appendix is less than 0.5% of all gastrointestinal cancers. The aim of this study was to analyse the incidence, symptoms, pathology and treatment of appendiceal adenocarcinoma in a well defined cohort as well as the prognosis of the patients. This is a retrospective study on al...
Main Authors: | , , |
---|---|
Format: | Article in Journal/Newspaper |
Language: | Icelandic |
Published: |
Læknafélag Íslands, Læknafélag Reykjavíkur
2011
|
Subjects: | |
Online Access: | http://hdl.handle.net/2336/182013 |
id |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/182013 |
---|---|
record_format |
openpolar |
spelling |
ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/182013 2023-05-15T16:49:08+02:00 Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn [Adenocarcinoma of the appendix in Iceland 1990-2009. A population based study]. Halla Viðarsdóttir Jón Gunnlaugur Jónasson Páll Helgi Möller 2011-10-28 http://hdl.handle.net/2336/182013 ice is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is/ Læknablaðið 2011, 97 (10):537-42 0023-7213 21998147 http://hdl.handle.net/2336/182013 Læknablaðið Krabbamein Botnlangaskurður Botnlangi Adenocarcinoma Appendix Article 2011 ftlandspitaliuni 2022-05-29T08:21:45Z Adenocarcinoma of the appendix is less than 0.5% of all gastrointestinal cancers. The aim of this study was to analyse the incidence, symptoms, pathology and treatment of appendiceal adenocarcinoma in a well defined cohort as well as the prognosis of the patients. This is a retrospective study on all patients diagnosed with adenocarcinoma of the appendix in Iceland from 1990-2009. Information on epidemiological factors, survival and treatment was collected. All histological material was reviewed. Overall survival was estimated with median follow up of 15 months (range, 0-158). A total of 22 patients were diagnosed with appendiceal adenocarinoma in the study period (median age 63 yrs, range: 30-88, 50% males). Age-standardized incidence was 0.4/100,000/year. The most common symptom was abdominal pain (n=10). Eight patients had clinical signs of appendicitis. Most patients were diagnosed at operation or at pathological examination but one patient was diagnosed at autopsy. Five patients had an appendectomy and 11 a right hemicolectomy. One patient was not operated on and in three patients only a biopsy was taken. Twelve patients had chemotherapy and seven of them for metastatic disease. Eight patients had adenocarcinoma, seven mucinous adenocarcinoma, three signet ring adenocarcinoma, one mixed goblet cell carcinoid and mucinous adenocarcinoma,one mixed adenocarcinoma and signet ring adenocarcinoma and two a mucinous tumour of unknown malignant potential. In eight cases the tumor originated in adenoma. Most of the patients had a stage IV disease (n=13), three stage III, three stage II and three stage I. Operative mortality was 4.8% (n=1). Disease specific five year survival was 54% but overall five year survival was 44% respectively. Adenocarcinoma of the appendix is a rare disease. No patients were diagnosed pre-operatively. Over half of the patients presented with stage IV disease. Tilgangur: Kirtilkrabbamein í botnlanga er innan við 0,5% krabbameina í meltingarvegi. Tilgangur rannsóknarinnar var að skoða ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Krabbamein Botnlangaskurður Botnlangi Adenocarcinoma Appendix |
spellingShingle |
Krabbamein Botnlangaskurður Botnlangi Adenocarcinoma Appendix Halla Viðarsdóttir Jón Gunnlaugur Jónasson Páll Helgi Möller Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
topic_facet |
Krabbamein Botnlangaskurður Botnlangi Adenocarcinoma Appendix |
description |
Adenocarcinoma of the appendix is less than 0.5% of all gastrointestinal cancers. The aim of this study was to analyse the incidence, symptoms, pathology and treatment of appendiceal adenocarcinoma in a well defined cohort as well as the prognosis of the patients. This is a retrospective study on all patients diagnosed with adenocarcinoma of the appendix in Iceland from 1990-2009. Information on epidemiological factors, survival and treatment was collected. All histological material was reviewed. Overall survival was estimated with median follow up of 15 months (range, 0-158). A total of 22 patients were diagnosed with appendiceal adenocarinoma in the study period (median age 63 yrs, range: 30-88, 50% males). Age-standardized incidence was 0.4/100,000/year. The most common symptom was abdominal pain (n=10). Eight patients had clinical signs of appendicitis. Most patients were diagnosed at operation or at pathological examination but one patient was diagnosed at autopsy. Five patients had an appendectomy and 11 a right hemicolectomy. One patient was not operated on and in three patients only a biopsy was taken. Twelve patients had chemotherapy and seven of them for metastatic disease. Eight patients had adenocarcinoma, seven mucinous adenocarcinoma, three signet ring adenocarcinoma, one mixed goblet cell carcinoid and mucinous adenocarcinoma,one mixed adenocarcinoma and signet ring adenocarcinoma and two a mucinous tumour of unknown malignant potential. In eight cases the tumor originated in adenoma. Most of the patients had a stage IV disease (n=13), three stage III, three stage II and three stage I. Operative mortality was 4.8% (n=1). Disease specific five year survival was 54% but overall five year survival was 44% respectively. Adenocarcinoma of the appendix is a rare disease. No patients were diagnosed pre-operatively. Over half of the patients presented with stage IV disease. Tilgangur: Kirtilkrabbamein í botnlanga er innan við 0,5% krabbameina í meltingarvegi. Tilgangur rannsóknarinnar var að skoða ... |
format |
Article in Journal/Newspaper |
author |
Halla Viðarsdóttir Jón Gunnlaugur Jónasson Páll Helgi Möller |
author_facet |
Halla Viðarsdóttir Jón Gunnlaugur Jónasson Páll Helgi Möller |
author_sort |
Halla Viðarsdóttir |
title |
Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
title_short |
Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
title_full |
Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
title_fullStr |
Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
title_full_unstemmed |
Kirtilkrabbamein í botnlanga á Íslandi 1990-2009 - lýðgrunduð rannsókn |
title_sort |
kirtilkrabbamein í botnlanga á íslandi 1990-2009 - lýðgrunduð rannsókn |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2011 |
url |
http://hdl.handle.net/2336/182013 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is/ Læknablaðið 2011, 97 (10):537-42 0023-7213 21998147 http://hdl.handle.net/2336/182013 Læknablaðið |
_version_ |
1766039209719627776 |