Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Objective: Tumours in the central nervous system are the second most common malignant diseases in children. With improved treatment, the number of survivors is increasing. Therefore, better knowledge of...
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Læknafélag Íslands, Læknafélag Reykjavíkur
2008
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/16315 2023-05-15T16:50:01+02:00 Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku Central nervous system tumours in Icelandic children; diagnoses, treatment results and late effects Hilma Hólm Ólafur Gísli Jónsson Árni V. Þórsson Bjarni Hannesson Guðmundur Kr. Jónmundsson Jón R. Kristinsson Ásgeir Haraldsson 2008-01-18 http://hdl.handle.net/2336/16315 ICE is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is/2002/1/fraedigreinar/nr/722/ Læknablaðið 2002, 88(1):21-7 0023-7213 16940661 http://hdl.handle.net/2336/16315 Læknablaðið Börn Aukaverkanir Miðtaugakerfi Æxli LBL12 Child Central Nervous System Neoplasms Article 2008 ftlandspitaliuni 2022-05-29T08:21:04Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Objective: Tumours in the central nervous system are the second most common malignant diseases in children. With improved treatment, the number of survivors is increasing. Therefore, better knowledge of the long-term effects of the disease and the therapy is needed. The aim of the current study was to find the incidence of central nervous system tumours in Iceland, evaluate the treatment results and study the long-term effects on the individuals. Material and methods: Data on diagnosis and treatment as well as demographic data were gathered from hospital records from the Reykjavik City Hospital and The University Hospital and operating lists at the Department of Neurosurgery were reviewed. On survivors, physical examination was carried out, blood tests and urine-analysis were done and hearing was tested. Social adaptation, school performance, memory, concentration and general well being were studied by a questionnaire. Results: In the years 1970-1995, 57 children, aged 16 and younger, were diagnosed in Iceland with central nervous system tumours, 30 girls and 27 boys. Two children with brain metastases were excluded. Of the 55 individuals, 38 are alive today, 19 girls and 19 boys. Seventeen children had astrocytoma, grade 1 or 2 and seven had astrocytoma of grade 3 or 4. Seven children had medulloblastoma, other tumours were less common. Four patients with benign tumours in the spine were excluded from the study; three are living abroad and three refused participation. Therefore, 28 patients were included in the further study, 15 males and 13 females. The mean age at diagnoses was 7 years and 8 months (7:8) (median 6:7 years, span 0:0-15:11), the mean age at study was 21:4 years (median 20:2 years, span 7:6-39:9) and the mean time from diagnosis until study was 12:8 years (median 11:5 years, span 2:5-26:3). The mean standard deviation score for height (SDS) was -0.63 at the time of study, five of the patients had ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Smella ENVELOPE(29.443,29.443,69.896,69.896) |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Börn Aukaverkanir Miðtaugakerfi Æxli LBL12 Child Central Nervous System Neoplasms |
spellingShingle |
Börn Aukaverkanir Miðtaugakerfi Æxli LBL12 Child Central Nervous System Neoplasms Hilma Hólm Ólafur Gísli Jónsson Árni V. Þórsson Bjarni Hannesson Guðmundur Kr. Jónmundsson Jón R. Kristinsson Ásgeir Haraldsson Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
topic_facet |
Börn Aukaverkanir Miðtaugakerfi Æxli LBL12 Child Central Nervous System Neoplasms |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open Objective: Tumours in the central nervous system are the second most common malignant diseases in children. With improved treatment, the number of survivors is increasing. Therefore, better knowledge of the long-term effects of the disease and the therapy is needed. The aim of the current study was to find the incidence of central nervous system tumours in Iceland, evaluate the treatment results and study the long-term effects on the individuals. Material and methods: Data on diagnosis and treatment as well as demographic data were gathered from hospital records from the Reykjavik City Hospital and The University Hospital and operating lists at the Department of Neurosurgery were reviewed. On survivors, physical examination was carried out, blood tests and urine-analysis were done and hearing was tested. Social adaptation, school performance, memory, concentration and general well being were studied by a questionnaire. Results: In the years 1970-1995, 57 children, aged 16 and younger, were diagnosed in Iceland with central nervous system tumours, 30 girls and 27 boys. Two children with brain metastases were excluded. Of the 55 individuals, 38 are alive today, 19 girls and 19 boys. Seventeen children had astrocytoma, grade 1 or 2 and seven had astrocytoma of grade 3 or 4. Seven children had medulloblastoma, other tumours were less common. Four patients with benign tumours in the spine were excluded from the study; three are living abroad and three refused participation. Therefore, 28 patients were included in the further study, 15 males and 13 females. The mean age at diagnoses was 7 years and 8 months (7:8) (median 6:7 years, span 0:0-15:11), the mean age at study was 21:4 years (median 20:2 years, span 7:6-39:9) and the mean time from diagnosis until study was 12:8 years (median 11:5 years, span 2:5-26:3). The mean standard deviation score for height (SDS) was -0.63 at the time of study, five of the patients had ... |
format |
Article in Journal/Newspaper |
author |
Hilma Hólm Ólafur Gísli Jónsson Árni V. Þórsson Bjarni Hannesson Guðmundur Kr. Jónmundsson Jón R. Kristinsson Ásgeir Haraldsson |
author_facet |
Hilma Hólm Ólafur Gísli Jónsson Árni V. Þórsson Bjarni Hannesson Guðmundur Kr. Jónmundsson Jón R. Kristinsson Ásgeir Haraldsson |
author_sort |
Hilma Hólm |
title |
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
title_short |
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
title_full |
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
title_fullStr |
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
title_full_unstemmed |
Greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
title_sort |
greining, árangur meðferðar og síðkomnar aukaverkanir æxla í miðtaugakerfi í æsku |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2008 |
url |
http://hdl.handle.net/2336/16315 |
long_lat |
ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
Smella |
geographic_facet |
Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is/2002/1/fraedigreinar/nr/722/ Læknablaðið 2002, 88(1):21-7 0023-7213 16940661 http://hdl.handle.net/2336/16315 Læknablaðið |
_version_ |
1766040195357999104 |