Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study.
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known. OBJECTIVE: To investi...
Published in: | Archives of Ophthalmology |
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American Medical Association
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Online Access: | http://hdl.handle.net/2336/15852 https://doi.org/10.1001/archopht.123.8.1102 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/15852 2023-05-15T16:52:20+02:00 Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. Rafnsson, Vilhjalmur Olafsdottir, Eydis Hrafnkelsson, Jon Sasaki, Hiroshi Arnarsson, Arsaell Jonasson, Fridbert Department of Preventive Medicine, University of Iceland, Neshagi 16, 107 Reykjavik, Iceland. vilraf@hi.is 2007-01-09 http://hdl.handle.net/2336/15852 https://doi.org/10.1001/archopht.123.8.1102 en eng American Medical Association http://archopht.ama-assn.org/cgi/content/abstract/123/8/1102 Arch. Ophthalmol. 2005, 123(8):1102-5 0003-9950 16087845 doi:10.1001/archopht.123.8.1102 http://hdl.handle.net/2336/15852 1538-3601 Archives of ophthalmology Aerospace Medicine Aged Aircraft Case-Control Studies Cataract Cosmic Radiation Humans Iceland Lens Nucleus Crystalline Male Middle Aged Occupational Exposure Odds Ratio Radiation Dosage Radiation Injuries Radiation Ionizing Risk Factors Article 2007 ftlandspitaliuni https://doi.org/10.1001/archopht.123.8.1102 2022-05-29T08:21:04Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known. OBJECTIVE: To investigate whether employment as a commercial airline pilot and the resulting exposure to cosmic radiation is associated with lens opacification. METHODS: This is a population-based case-control study of 445 men. Lens opacification was classified into 4 types using the World Health Organization simplified grading system. These 4 types, serving as cases, included 71 persons with nuclear cataracts, 102 with cortical lens opacification, 69 with central optical zone involvement, and 32 with posterior subcapsular lens opacification. Control subjects are those with a different type of lens opacification or without lens opacification. Exposure was assessed based on employment time as pilots, annual number of hours flown on each aircraft type, time tables, flight profiles, and individual cumulative radiation doses (in millisieverts) calculated by a software program. Odds ratios were calculated using logistic regression. RESULTS: The odds ratio for nuclear cataract risk among cases and controls was 3.02 (95% confidence interval, 1.44-6.35) for pilots compared with nonpilots, adjusted for age, smoking status, and sunbathing habits. The odds ratio for nuclear cataract associated with estimation of cumulative radiation dose (in millisieverts) to the age of 40 years was 1.06 (95% confidence interval, 1.02-1.10), adjusted for age, smoking status, and sunbathing habits. CONCLUSION: The association between the cosmic radiation exposure of pilots and the risk of nuclear cataracts, adjusted for age, smoking status, and sunbathing habits, indicates that cosmic radiation may be a causative factor in nuclear cataracts among commercial airline pilots. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Archives of Ophthalmology 123 8 1102 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Aerospace Medicine Aged Aircraft Case-Control Studies Cataract Cosmic Radiation Humans Iceland Lens Nucleus Crystalline Male Middle Aged Occupational Exposure Odds Ratio Radiation Dosage Radiation Injuries Radiation Ionizing Risk Factors |
spellingShingle |
Aerospace Medicine Aged Aircraft Case-Control Studies Cataract Cosmic Radiation Humans Iceland Lens Nucleus Crystalline Male Middle Aged Occupational Exposure Odds Ratio Radiation Dosage Radiation Injuries Radiation Ionizing Risk Factors Rafnsson, Vilhjalmur Olafsdottir, Eydis Hrafnkelsson, Jon Sasaki, Hiroshi Arnarsson, Arsaell Jonasson, Fridbert Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
topic_facet |
Aerospace Medicine Aged Aircraft Case-Control Studies Cataract Cosmic Radiation Humans Iceland Lens Nucleus Crystalline Male Middle Aged Occupational Exposure Odds Ratio Radiation Dosage Radiation Injuries Radiation Ionizing Risk Factors |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field BACKGROUND: Aviation involves exposure to ionizing radiation of cosmic origin. The association between lesions of the ocular lens and ionizing radiation is well-known. OBJECTIVE: To investigate whether employment as a commercial airline pilot and the resulting exposure to cosmic radiation is associated with lens opacification. METHODS: This is a population-based case-control study of 445 men. Lens opacification was classified into 4 types using the World Health Organization simplified grading system. These 4 types, serving as cases, included 71 persons with nuclear cataracts, 102 with cortical lens opacification, 69 with central optical zone involvement, and 32 with posterior subcapsular lens opacification. Control subjects are those with a different type of lens opacification or without lens opacification. Exposure was assessed based on employment time as pilots, annual number of hours flown on each aircraft type, time tables, flight profiles, and individual cumulative radiation doses (in millisieverts) calculated by a software program. Odds ratios were calculated using logistic regression. RESULTS: The odds ratio for nuclear cataract risk among cases and controls was 3.02 (95% confidence interval, 1.44-6.35) for pilots compared with nonpilots, adjusted for age, smoking status, and sunbathing habits. The odds ratio for nuclear cataract associated with estimation of cumulative radiation dose (in millisieverts) to the age of 40 years was 1.06 (95% confidence interval, 1.02-1.10), adjusted for age, smoking status, and sunbathing habits. CONCLUSION: The association between the cosmic radiation exposure of pilots and the risk of nuclear cataracts, adjusted for age, smoking status, and sunbathing habits, indicates that cosmic radiation may be a causative factor in nuclear cataracts among commercial airline pilots. |
author2 |
Department of Preventive Medicine, University of Iceland, Neshagi 16, 107 Reykjavik, Iceland. vilraf@hi.is |
format |
Article in Journal/Newspaper |
author |
Rafnsson, Vilhjalmur Olafsdottir, Eydis Hrafnkelsson, Jon Sasaki, Hiroshi Arnarsson, Arsaell Jonasson, Fridbert |
author_facet |
Rafnsson, Vilhjalmur Olafsdottir, Eydis Hrafnkelsson, Jon Sasaki, Hiroshi Arnarsson, Arsaell Jonasson, Fridbert |
author_sort |
Rafnsson, Vilhjalmur |
title |
Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
title_short |
Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
title_full |
Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
title_fullStr |
Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
title_full_unstemmed |
Cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
title_sort |
cosmic radiation increases the risk of nuclear cataract in airline pilots: a population-based case-control study. |
publisher |
American Medical Association |
publishDate |
2007 |
url |
http://hdl.handle.net/2336/15852 https://doi.org/10.1001/archopht.123.8.1102 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://archopht.ama-assn.org/cgi/content/abstract/123/8/1102 Arch. Ophthalmol. 2005, 123(8):1102-5 0003-9950 16087845 doi:10.1001/archopht.123.8.1102 http://hdl.handle.net/2336/15852 1538-3601 Archives of ophthalmology |
op_doi |
https://doi.org/10.1001/archopht.123.8.1102 |
container_title |
Archives of Ophthalmology |
container_volume |
123 |
container_issue |
8 |
container_start_page |
1102 |
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1766042472263188480 |