Autism spectrum disorders in children with seizures in the first year of life - a population-based study
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To describe autistic spectrum disorders (ASDs) in a cohort of children with history of unprovoked seizures other than infantile spasms in the first year of life. METHODS: The sourc...
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Online Access: | http://hdl.handle.net/2336/14436 https://doi.org/10.1111/j.1528-1167.2007.01150.x |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/14436 2023-05-15T16:48:44+02:00 Autism spectrum disorders in children with seizures in the first year of life - a population-based study Saemundsen, Evald Ludvigsson, Petur Hilmarsdottir, Ingibjorg Rafnsson, Vilhjalmur 2007-11-02 YES http://hdl.handle.net/2336/14436 https://doi.org/10.1111/j.1528-1167.2007.01150.x en eng Blackwell Science http://onlinelibrary.wiley.com/doi/abs/10.1111/j.1528-1167.2007.01150.x Epilepsia 2007, 48(9):1724-30 0013-9580 17555525 doi:10.1111/j.1528-1167.2007.01150.x http://hdl.handle.net/2336/14436 Epilepsia Autistic Disorder Iceland/epidemiology Intelligence Tests Family Age of Onset Psychiatric Status Rating Scales Questionnaires Article 2007 ftlandspitaliuni https://doi.org/10.1111/j.1528-1167.2007.01150.x 2022-05-29T08:21:02Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To describe autistic spectrum disorders (ASDs) in a cohort of children with history of unprovoked seizures other than infantile spasms in the first year of life. METHODS: The source of data was computer records from all the three pediatric departments in Iceland. Children diagnosed 1982-2000 with unprovoked seizures with onset between 28 days and 12 months of age (N = 102) were invited to participate in a study. Children with known developmental disorders and those whose parents had concerns regarding their child's development or behavior were investigated for possible ASD. Parents were asked to complete the Social Communication Questionnaire and children scoring 10 points or higher were further examined with the Autism Diagnostic Interview-Revised and observational measures. RESULTS: Eighty-four children (82.4%), 28 boys and 56 girls, participated in the study and 36.9% (31/84) were investigated for possible ASD. Twenty-four (28.6%) had at least one neurodevelopmental disorder, 14.3% had mental retardation (MR), and six (7.1%) were diagnosed with ASD, all of whom also had MR and three of whom had congenital brain abnormalities. CONCLUSION: These results suggest that the estimated prevalence of ASD is higher in children with history of seizure in the first year of life than it is in the general population. There are indications that support the view that children with ASD and history of seizure in the first year of life have higher prevalence of congenital brain abnormalities and are more often female, than other children with ASD. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Epilepsia 48 9 1724 1730 |
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Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Autistic Disorder Iceland/epidemiology Intelligence Tests Family Age of Onset Psychiatric Status Rating Scales Questionnaires |
spellingShingle |
Autistic Disorder Iceland/epidemiology Intelligence Tests Family Age of Onset Psychiatric Status Rating Scales Questionnaires Saemundsen, Evald Ludvigsson, Petur Hilmarsdottir, Ingibjorg Rafnsson, Vilhjalmur Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
topic_facet |
Autistic Disorder Iceland/epidemiology Intelligence Tests Family Age of Onset Psychiatric Status Rating Scales Questionnaires |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field PURPOSE: To describe autistic spectrum disorders (ASDs) in a cohort of children with history of unprovoked seizures other than infantile spasms in the first year of life. METHODS: The source of data was computer records from all the three pediatric departments in Iceland. Children diagnosed 1982-2000 with unprovoked seizures with onset between 28 days and 12 months of age (N = 102) were invited to participate in a study. Children with known developmental disorders and those whose parents had concerns regarding their child's development or behavior were investigated for possible ASD. Parents were asked to complete the Social Communication Questionnaire and children scoring 10 points or higher were further examined with the Autism Diagnostic Interview-Revised and observational measures. RESULTS: Eighty-four children (82.4%), 28 boys and 56 girls, participated in the study and 36.9% (31/84) were investigated for possible ASD. Twenty-four (28.6%) had at least one neurodevelopmental disorder, 14.3% had mental retardation (MR), and six (7.1%) were diagnosed with ASD, all of whom also had MR and three of whom had congenital brain abnormalities. CONCLUSION: These results suggest that the estimated prevalence of ASD is higher in children with history of seizure in the first year of life than it is in the general population. There are indications that support the view that children with ASD and history of seizure in the first year of life have higher prevalence of congenital brain abnormalities and are more often female, than other children with ASD. |
format |
Article in Journal/Newspaper |
author |
Saemundsen, Evald Ludvigsson, Petur Hilmarsdottir, Ingibjorg Rafnsson, Vilhjalmur |
author_facet |
Saemundsen, Evald Ludvigsson, Petur Hilmarsdottir, Ingibjorg Rafnsson, Vilhjalmur |
author_sort |
Saemundsen, Evald |
title |
Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
title_short |
Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
title_full |
Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
title_fullStr |
Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
title_full_unstemmed |
Autism spectrum disorders in children with seizures in the first year of life - a population-based study |
title_sort |
autism spectrum disorders in children with seizures in the first year of life - a population-based study |
publisher |
Blackwell Science |
publishDate |
2007 |
url |
http://hdl.handle.net/2336/14436 https://doi.org/10.1111/j.1528-1167.2007.01150.x |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://onlinelibrary.wiley.com/doi/abs/10.1111/j.1528-1167.2007.01150.x Epilepsia 2007, 48(9):1724-30 0013-9580 17555525 doi:10.1111/j.1528-1167.2007.01150.x http://hdl.handle.net/2336/14436 Epilepsia |
op_doi |
https://doi.org/10.1111/j.1528-1167.2007.01150.x |
container_title |
Epilepsia |
container_volume |
48 |
container_issue |
9 |
container_start_page |
1724 |
op_container_end_page |
1730 |
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1766038820201955328 |