Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open) Introduction: A sublobar resection is performed on patients with non-small cell lung cancer (NSCLC) who are not candidates for a lobectomy due to reduced pulmonary function or comorbid diseas...
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Læknafélag Íslands, Læknafélag Reykjavíkur
2011
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Online Access: | http://hdl.handle.net/2336/129341 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/129341 2023-05-15T16:47:43+02:00 Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi Sublobar resection for non-small cell lung cancer in Iceland Ásgeir Alexandersson Steinn Jónsson Helgi J. Ísaksson Tómas Guðbjartsson 2011-05-10 http://hdl.handle.net/2336/129341 is ice Læknafélag Íslands, Læknafélag Reykjavíkur http://www.laeknabladid.is Læknablaðið 2011, 97(5):304-8 1022-2278 http://hdl.handle.net/2336/129341 Læknablaðið Lungnakrabbamein Lung Neoplasms Carcinoma Non-Small-Cell Lung Survival PubMed - in process Article 2011 ftlandspitaliuni 2022-05-29T08:21:45Z Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open) Introduction: A sublobar resection is performed on patients with non-small cell lung cancer (NSCLC) who are not candidates for a lobectomy due to reduced pulmonary function or comorbid disease. The aim of this study was to investigate the outcomes of these operations in Iceland. Material and methods: A retrospective study of all patients with NSCLC who underwent wedge resection or segmentectomy with curative intent during 1994-2008. Data on indication, pathological TNM-stage, complications and overall survival was analyzed. All histological samples were re-evaluated. Results: Forty four patients underwent 42 wedge and 5 segmental resections (age 69.1 yrs, 55.3% female), with 38.3% of cases detected incidentally. The majority of patients (55.3%) had a history of coronary artery disease and 40.4% had chronic obstructive pulmonary disease. Mean operative time was 83 minutes (range 30-131), mean intraoperative bleeding was 260 ml (range 100-650) and median hospital stay was 9 days (range 4-24). Pneumonia (14.9%) and prolonged air leakage (12.8%) were the most common complications. Two patients had major complications and 36.2% stayed in the intensive care unit overnight. No deaths occurred within 30 days of surgery. Adenocarcinoma was the most common histological type (66.7%). Most cases were stage IA/IB (78.7%), 17.0% were stage IIA/IIB and 4.3% were stage IIIA. One and 5 year survival was 85.1% and 40.9% respectively. Conclusion: In Iceland, both survival and complication rate after sublobar resection for NSCLC are comparable to results published for lobectomies, even though a higher percentage of patients have underlying cardiopulmonary disease. Inngangur: Hefðbundin aðgerð við lungnakrabbameini öðru en smáfrumukrabbameini er blaðnám. Í völdum tilvikum, einkum þegar lungnastarfsemi er mikið skert, er gripið til fleyg- eða geiraskurðar. Markmið þessarar rannsóknar var að kanna árangur þessara aðgerða ... Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive TNM ENVELOPE(-58.100,-58.100,-62.000,-62.000) Smella ENVELOPE(29.443,29.443,69.896,69.896) |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
Icelandic |
topic |
Lungnakrabbamein Lung Neoplasms Carcinoma Non-Small-Cell Lung Survival PubMed - in process |
spellingShingle |
Lungnakrabbamein Lung Neoplasms Carcinoma Non-Small-Cell Lung Survival PubMed - in process Ásgeir Alexandersson Steinn Jónsson Helgi J. Ísaksson Tómas Guðbjartsson Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
topic_facet |
Lungnakrabbamein Lung Neoplasms Carcinoma Non-Small-Cell Lung Survival PubMed - in process |
description |
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn Skoða/Opna(view/open) Introduction: A sublobar resection is performed on patients with non-small cell lung cancer (NSCLC) who are not candidates for a lobectomy due to reduced pulmonary function or comorbid disease. The aim of this study was to investigate the outcomes of these operations in Iceland. Material and methods: A retrospective study of all patients with NSCLC who underwent wedge resection or segmentectomy with curative intent during 1994-2008. Data on indication, pathological TNM-stage, complications and overall survival was analyzed. All histological samples were re-evaluated. Results: Forty four patients underwent 42 wedge and 5 segmental resections (age 69.1 yrs, 55.3% female), with 38.3% of cases detected incidentally. The majority of patients (55.3%) had a history of coronary artery disease and 40.4% had chronic obstructive pulmonary disease. Mean operative time was 83 minutes (range 30-131), mean intraoperative bleeding was 260 ml (range 100-650) and median hospital stay was 9 days (range 4-24). Pneumonia (14.9%) and prolonged air leakage (12.8%) were the most common complications. Two patients had major complications and 36.2% stayed in the intensive care unit overnight. No deaths occurred within 30 days of surgery. Adenocarcinoma was the most common histological type (66.7%). Most cases were stage IA/IB (78.7%), 17.0% were stage IIA/IIB and 4.3% were stage IIIA. One and 5 year survival was 85.1% and 40.9% respectively. Conclusion: In Iceland, both survival and complication rate after sublobar resection for NSCLC are comparable to results published for lobectomies, even though a higher percentage of patients have underlying cardiopulmonary disease. Inngangur: Hefðbundin aðgerð við lungnakrabbameini öðru en smáfrumukrabbameini er blaðnám. Í völdum tilvikum, einkum þegar lungnastarfsemi er mikið skert, er gripið til fleyg- eða geiraskurðar. Markmið þessarar rannsóknar var að kanna árangur þessara aðgerða ... |
format |
Article in Journal/Newspaper |
author |
Ásgeir Alexandersson Steinn Jónsson Helgi J. Ísaksson Tómas Guðbjartsson |
author_facet |
Ásgeir Alexandersson Steinn Jónsson Helgi J. Ísaksson Tómas Guðbjartsson |
author_sort |
Ásgeir Alexandersson |
title |
Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
title_short |
Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
title_full |
Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
title_fullStr |
Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
title_full_unstemmed |
Árangur fleyg- og geiraskurða við lungnakrabbameini á Íslandi |
title_sort |
árangur fleyg- og geiraskurða við lungnakrabbameini á íslandi |
publisher |
Læknafélag Íslands, Læknafélag Reykjavíkur |
publishDate |
2011 |
url |
http://hdl.handle.net/2336/129341 |
long_lat |
ENVELOPE(-58.100,-58.100,-62.000,-62.000) ENVELOPE(29.443,29.443,69.896,69.896) |
geographic |
TNM Smella |
geographic_facet |
TNM Smella |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://www.laeknabladid.is Læknablaðið 2011, 97(5):304-8 1022-2278 http://hdl.handle.net/2336/129341 Læknablaðið |
_version_ |
1766037811896516608 |