A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The epidemiology of peripheral vascular disease has been studied much less extensively than the epidemiology of coronary heart disease (CHD). The prospective Reykjavik Study gave an opportu...
Published in: | Journal of Clinical Epidemiology |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/120510 2023-05-15T16:48:11+02:00 A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study Ingolfsson, I O Sigurdsson, G Sigvaldason, H Thorgeirsson, G Sigfusson, N Department of Medicine, Reykjavik City Hospital, University of Iceland 2011-01-27 http://hdl.handle.net/2336/120510 https://doi.org/10.1016/0895-4356(94)90128-7 en eng Elsevier http://dx.doi.org/10.1016/0895-4356(94)90128-7 J Clin Epidemiol 1994, 47(11):1237-43 0895-4356 7722559 doi:10.1016/0895-4356(94)90128-7 http://hdl.handle.net/2336/120510 Journal of clinical epidemiology Adult Aged Cholesterol Epidemiology Humans Iceland Incidence Intermittent Claudication Logistic Models Male Middle Aged Multivariate Analysis Prevalence Prospective Studies Risk Factors Smoking Article 2011 ftlandspitaliuni https://doi.org/10.1016/0895-4356(94)90128-7 2022-05-29T08:21:41Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The epidemiology of peripheral vascular disease has been studied much less extensively than the epidemiology of coronary heart disease (CHD). The prospective Reykjavik Study gave an opportunity to monitor secular trends from 1968 to 1986 of clinical intermittent claudication (IC) amongst Icelandic males, aged 34-80 and to assess the importance of possible risk factors. Both prevalence and incidence of IC decreased sharply after 1970 in all age groups, and this decline occurred a few years earlier than the decline of CHD in Iceland. The only significant risk factors for intermittent claudication, in addition to age, were smoking which increased the risk of IC 8- to 10-fold and serum cholesterol level. Approximately one-half of the striking decline in the incidence of IC can be explained by decreased smoking and cholesterol levels amongst Icelandic men. A follow-up study verified that IC patients stood twice the risk of cardiovascular and total mortality as non-IC patients, indicating that IC is a high risk group which should receive all possible preventive measures. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Journal of Clinical Epidemiology 47 11 1237 1243 |
institution |
Open Polar |
collection |
Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adult Aged Cholesterol Epidemiology Humans Iceland Incidence Intermittent Claudication Logistic Models Male Middle Aged Multivariate Analysis Prevalence Prospective Studies Risk Factors Smoking |
spellingShingle |
Adult Aged Cholesterol Epidemiology Humans Iceland Incidence Intermittent Claudication Logistic Models Male Middle Aged Multivariate Analysis Prevalence Prospective Studies Risk Factors Smoking Ingolfsson, I O Sigurdsson, G Sigvaldason, H Thorgeirsson, G Sigfusson, N A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
topic_facet |
Adult Aged Cholesterol Epidemiology Humans Iceland Incidence Intermittent Claudication Logistic Models Male Middle Aged Multivariate Analysis Prevalence Prospective Studies Risk Factors Smoking |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The epidemiology of peripheral vascular disease has been studied much less extensively than the epidemiology of coronary heart disease (CHD). The prospective Reykjavik Study gave an opportunity to monitor secular trends from 1968 to 1986 of clinical intermittent claudication (IC) amongst Icelandic males, aged 34-80 and to assess the importance of possible risk factors. Both prevalence and incidence of IC decreased sharply after 1970 in all age groups, and this decline occurred a few years earlier than the decline of CHD in Iceland. The only significant risk factors for intermittent claudication, in addition to age, were smoking which increased the risk of IC 8- to 10-fold and serum cholesterol level. Approximately one-half of the striking decline in the incidence of IC can be explained by decreased smoking and cholesterol levels amongst Icelandic men. A follow-up study verified that IC patients stood twice the risk of cardiovascular and total mortality as non-IC patients, indicating that IC is a high risk group which should receive all possible preventive measures. |
author2 |
Department of Medicine, Reykjavik City Hospital, University of Iceland |
format |
Article in Journal/Newspaper |
author |
Ingolfsson, I O Sigurdsson, G Sigvaldason, H Thorgeirsson, G Sigfusson, N |
author_facet |
Ingolfsson, I O Sigurdsson, G Sigvaldason, H Thorgeirsson, G Sigfusson, N |
author_sort |
Ingolfsson, I O |
title |
A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
title_short |
A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
title_full |
A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
title_fullStr |
A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
title_full_unstemmed |
A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the Reykjavik Study |
title_sort |
marked decline in the prevalence and incidence of intermittent claudication in icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol--the reykjavik study |
publisher |
Elsevier |
publishDate |
2011 |
url |
http://hdl.handle.net/2336/120510 https://doi.org/10.1016/0895-4356(94)90128-7 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.1016/0895-4356(94)90128-7 J Clin Epidemiol 1994, 47(11):1237-43 0895-4356 7722559 doi:10.1016/0895-4356(94)90128-7 http://hdl.handle.net/2336/120510 Journal of clinical epidemiology |
op_doi |
https://doi.org/10.1016/0895-4356(94)90128-7 |
container_title |
Journal of Clinical Epidemiology |
container_volume |
47 |
container_issue |
11 |
container_start_page |
1237 |
op_container_end_page |
1243 |
_version_ |
1766038294913613824 |