A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The significance of incidental diagnosing in relation to survival of renal cell carcinoma (RCC) patients is not known. A retrospective, population-based study was carried out in order to ev...
Published in: | Scandinavian Journal of Urology and Nephrology |
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Online Access: | http://hdl.handle.net/2336/111856 https://doi.org/10.3109/00365599609182322 |
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ftlandspitaliuni:oai:www.hirsla.lsh.is:2336/111856 2023-05-15T16:46:44+02:00 A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 Gudbjartsson, T Einarsson, G V Magnusson, J Department of Urology, Landspítalinn, University Hospital, Reykjavík, Iceland. 2010-09-27 http://hdl.handle.net/2336/111856 https://doi.org/10.3109/00365599609182322 en eng Taylor & Francis http://dx.doi.org/10.3109/00365599609182322 Scand. J. Urol. Nephrol. 1996, 30(6):451-5 0036-5599 9008024 doi:10.3109/00365599609182322 http://hdl.handle.net/2336/111856 Scandinavian journal of urology and nephrology Adolescent Adult Aged 80 and over Carcinoma Renal Cell Cross-Cultural Comparison Cross-Sectional Studies Humans Iceland Incidence Kidney Neoplasms Middle Aged Neoplasm Staging Retrospective Studies Article 2010 ftlandspitaliuni https://doi.org/10.3109/00365599609182322 2022-05-29T08:21:37Z To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The significance of incidental diagnosing in relation to survival of renal cell carcinoma (RCC) patients is not known. A retrospective, population-based study was carried out in order to evaluate the survival of RCC patients, with emphasis on incidental diagnosing. Included in the study were all patients diagnosed with RCC in Iceland between 1971 and 1990. The tumours were classified and the extent of the disease staged by Robson's method. Crude probability of survival was evaluated for every stage, and multivariate analysis applied in order to determine prognostic factors. Out of 408 patients, 15% were diagnosed incidentally between 1971 and 1980 and 20% between 1981 and 1990 (p > 0.1), most often by intravenous urography. Only 5 tumours were detected incidentally by ultrasound techniques and 4 by CT scans. Crude five-year survival was 76% for stage I disease and 11% for stage IV disease. After correction for staging by multivariate analysis, incidental diagnosis and the year of diagnosis were not independent significant prognostic factors for mortality. As in many other studies, our data indicate that incidentally diagnosed RCCs are at a lower stage at the time of diagnosis. On the other hand, the results of our population-based study show that ultrasound and CT scanning have not significantly increased the number of incidentally diagnosed tumours. It is therefore not very surprising that surviving of RCC patients in Iceland has remained the same for the last two decades. Article in Journal/Newspaper Iceland Hirsla - Landspítali University Hospital research archive Scandinavian Journal of Urology and Nephrology 30 6 451 455 |
institution |
Open Polar |
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Hirsla - Landspítali University Hospital research archive |
op_collection_id |
ftlandspitaliuni |
language |
English |
topic |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Cross-Cultural Comparison Cross-Sectional Studies Humans Iceland Incidence Kidney Neoplasms Middle Aged Neoplasm Staging Retrospective Studies |
spellingShingle |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Cross-Cultural Comparison Cross-Sectional Studies Humans Iceland Incidence Kidney Neoplasms Middle Aged Neoplasm Staging Retrospective Studies Gudbjartsson, T Einarsson, G V Magnusson, J A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
topic_facet |
Adolescent Adult Aged 80 and over Carcinoma Renal Cell Cross-Cultural Comparison Cross-Sectional Studies Humans Iceland Incidence Kidney Neoplasms Middle Aged Neoplasm Staging Retrospective Studies |
description |
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field The significance of incidental diagnosing in relation to survival of renal cell carcinoma (RCC) patients is not known. A retrospective, population-based study was carried out in order to evaluate the survival of RCC patients, with emphasis on incidental diagnosing. Included in the study were all patients diagnosed with RCC in Iceland between 1971 and 1990. The tumours were classified and the extent of the disease staged by Robson's method. Crude probability of survival was evaluated for every stage, and multivariate analysis applied in order to determine prognostic factors. Out of 408 patients, 15% were diagnosed incidentally between 1971 and 1980 and 20% between 1981 and 1990 (p > 0.1), most often by intravenous urography. Only 5 tumours were detected incidentally by ultrasound techniques and 4 by CT scans. Crude five-year survival was 76% for stage I disease and 11% for stage IV disease. After correction for staging by multivariate analysis, incidental diagnosis and the year of diagnosis were not independent significant prognostic factors for mortality. As in many other studies, our data indicate that incidentally diagnosed RCCs are at a lower stage at the time of diagnosis. On the other hand, the results of our population-based study show that ultrasound and CT scanning have not significantly increased the number of incidentally diagnosed tumours. It is therefore not very surprising that surviving of RCC patients in Iceland has remained the same for the last two decades. |
author2 |
Department of Urology, Landspítalinn, University Hospital, Reykjavík, Iceland. |
format |
Article in Journal/Newspaper |
author |
Gudbjartsson, T Einarsson, G V Magnusson, J |
author_facet |
Gudbjartsson, T Einarsson, G V Magnusson, J |
author_sort |
Gudbjartsson, T |
title |
A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
title_short |
A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
title_full |
A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
title_fullStr |
A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
title_full_unstemmed |
A population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in Iceland, 1971-1990 |
title_sort |
population-based analysis of survival and incidental diagnosing of renal cell carcinoma patients in iceland, 1971-1990 |
publisher |
Taylor & Francis |
publishDate |
2010 |
url |
http://hdl.handle.net/2336/111856 https://doi.org/10.3109/00365599609182322 |
genre |
Iceland |
genre_facet |
Iceland |
op_relation |
http://dx.doi.org/10.3109/00365599609182322 Scand. J. Urol. Nephrol. 1996, 30(6):451-5 0036-5599 9008024 doi:10.3109/00365599609182322 http://hdl.handle.net/2336/111856 Scandinavian journal of urology and nephrology |
op_doi |
https://doi.org/10.3109/00365599609182322 |
container_title |
Scandinavian Journal of Urology and Nephrology |
container_volume |
30 |
container_issue |
6 |
container_start_page |
451 |
op_container_end_page |
455 |
_version_ |
1766036834222080000 |