Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom
To investigate possible relationships between polychlorinated biphenyl (PCB) exposure and infectious disease mortality in harbor porpoises (Phocoena phocoena) in United Kingdom waters, summed blubber concentrations of 25 chlorobiphenyl congeners (Sigma25CB) in healthy harbor porpoises that died of a...
Published in: | Environmental Toxicology and Chemistry |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | unknown |
Published: |
SETAC
2005
|
Subjects: | |
Online Access: | https://kar.kent.ac.uk/7514/ https://doi.org/10.1897/03-663.1 |
id |
ftkentuniv:oai:kar.kent.ac.uk:7514 |
---|---|
record_format |
openpolar |
spelling |
ftkentuniv:oai:kar.kent.ac.uk:7514 2024-06-09T07:49:03+00:00 Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom Jepson, Paul D. Bennett, Peter M. Deaville, Robert Allchin, Colin R. Baker, John R. Law, Robin J. 2005-01 https://kar.kent.ac.uk/7514/ https://doi.org/10.1897/03-663.1 unknown SETAC Jepson, Paul D., Bennett, Peter M., Deaville, Robert, Allchin, Colin R., Baker, John R., Law, Robin J. (2005) Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom. Environmental Toxicology and Chemistry, 24 (1). pp. 238-248. ISSN 0730-7268. (doi:10.1897/03-663.1 <https://doi.org/10.1897/03-663.1>) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:7514 </7514>) GE Environmental Sciences GN Anthropology Article PeerReviewed 2005 ftkentuniv https://doi.org/10.1897/03-663.1 2024-05-16T04:17:29Z To investigate possible relationships between polychlorinated biphenyl (PCB) exposure and infectious disease mortality in harbor porpoises (Phocoena phocoena) in United Kingdom waters, summed blubber concentrations of 25 chlorobiphenyl congeners (Sigma25CB) in healthy harbor porpoises that died of acute physical trauma (mainly by-catch; n = 175) were compared with Sigma25CB values in animals that died of infectious disease (n = 82). The infectious disease group had significantly greater Sigma25CB values (mean, 27.6 mg/kg lipid) than the physical trauma group (mean, 13.6 mg/kg lipid; p < 0.001). This association occurred independently of other potentially confounding variables, including age, sex, two indices of nutritional status, season, region, and year found. Total blubber PCB levels (as Aroclor 1254) were also calculated, enabling direct comparison with a proposed threshold for adverse health effects (including immunosuppression) in marine mammals of 17 mg/kg lipid. In porpoises with total PCB levels greater than 17 mg/kg lipid (n = 154), total PCB levels were significantly higher in the infectious disease group compared to the physical trauma group (p < 0.001). This association was no longer significant in porpoises with total PCB levels of less than 17 mg/kg lipid (n = 103; p > 0.55). These findings are consistent with a causal (immunotoxic) relationship between PCB exposure and infectious disease mortality, and they provide a framework for future quantitative risk-assessment analyses of porpoise populations of known size and PCB exposure. Article in Journal/Newspaper Phocoena phocoena University of Kent: KAR - Kent Academic Repository Environmental Toxicology and Chemistry 24 1 238 |
institution |
Open Polar |
collection |
University of Kent: KAR - Kent Academic Repository |
op_collection_id |
ftkentuniv |
language |
unknown |
topic |
GE Environmental Sciences GN Anthropology |
spellingShingle |
GE Environmental Sciences GN Anthropology Jepson, Paul D. Bennett, Peter M. Deaville, Robert Allchin, Colin R. Baker, John R. Law, Robin J. Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
topic_facet |
GE Environmental Sciences GN Anthropology |
description |
To investigate possible relationships between polychlorinated biphenyl (PCB) exposure and infectious disease mortality in harbor porpoises (Phocoena phocoena) in United Kingdom waters, summed blubber concentrations of 25 chlorobiphenyl congeners (Sigma25CB) in healthy harbor porpoises that died of acute physical trauma (mainly by-catch; n = 175) were compared with Sigma25CB values in animals that died of infectious disease (n = 82). The infectious disease group had significantly greater Sigma25CB values (mean, 27.6 mg/kg lipid) than the physical trauma group (mean, 13.6 mg/kg lipid; p < 0.001). This association occurred independently of other potentially confounding variables, including age, sex, two indices of nutritional status, season, region, and year found. Total blubber PCB levels (as Aroclor 1254) were also calculated, enabling direct comparison with a proposed threshold for adverse health effects (including immunosuppression) in marine mammals of 17 mg/kg lipid. In porpoises with total PCB levels greater than 17 mg/kg lipid (n = 154), total PCB levels were significantly higher in the infectious disease group compared to the physical trauma group (p < 0.001). This association was no longer significant in porpoises with total PCB levels of less than 17 mg/kg lipid (n = 103; p > 0.55). These findings are consistent with a causal (immunotoxic) relationship between PCB exposure and infectious disease mortality, and they provide a framework for future quantitative risk-assessment analyses of porpoise populations of known size and PCB exposure. |
format |
Article in Journal/Newspaper |
author |
Jepson, Paul D. Bennett, Peter M. Deaville, Robert Allchin, Colin R. Baker, John R. Law, Robin J. |
author_facet |
Jepson, Paul D. Bennett, Peter M. Deaville, Robert Allchin, Colin R. Baker, John R. Law, Robin J. |
author_sort |
Jepson, Paul D. |
title |
Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
title_short |
Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
title_full |
Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
title_fullStr |
Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
title_full_unstemmed |
Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom |
title_sort |
relationships between polychlorinated biphenyls and health status in harbor porpoises (phocoena phocoena) stranded in the united kingdom |
publisher |
SETAC |
publishDate |
2005 |
url |
https://kar.kent.ac.uk/7514/ https://doi.org/10.1897/03-663.1 |
genre |
Phocoena phocoena |
genre_facet |
Phocoena phocoena |
op_relation |
Jepson, Paul D., Bennett, Peter M., Deaville, Robert, Allchin, Colin R., Baker, John R., Law, Robin J. (2005) Relationships between polychlorinated biphenyls and health status in harbor porpoises (Phocoena phocoena) stranded in the United Kingdom. Environmental Toxicology and Chemistry, 24 (1). pp. 238-248. ISSN 0730-7268. (doi:10.1897/03-663.1 <https://doi.org/10.1897/03-663.1>) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:7514 </7514>) |
op_doi |
https://doi.org/10.1897/03-663.1 |
container_title |
Environmental Toxicology and Chemistry |
container_volume |
24 |
container_issue |
1 |
container_start_page |
238 |
_version_ |
1801381140179714048 |