Comprehensive analysis of the 5-HTTLPR allelic polymorphism effect on behavioral and neurophysiological indicators of executive control in people from different ethnic groups in Siberia

• Published in: Vavilov Journal of Genetics and Breeding
• Main Authors: A. N. Savostyanov, D. V. Bazovkina, S. A. Lashin, S. S. Tamozhnikov, A. E. Saprygin, T. N. Astakhova, U. N. Kavai-ool, N. V. Borisova, A. G. Karpova, А. Н. Савостьянов, Д. В. Базовкина, С. А. Лашин, С. С. Таможников, А. Е. Сапрыгин, Т. Н. Астахова, У. Н. Кавай-оол, Н. В. Борисова, А. Г. Карпова
• Other Authors: The research was carried out with financial support from the Russian Foundation for Basic Research (grant No. 18-29-13027). The work of A.N. Savostyanov, A.E. Saprygin, and S.A. Lashin was supported from the funds of the budget project No. 0259-2021-0009 at the Institute of Cytology and Genetics of the SB RAS.
• Format: Article in Journal/Newspaper
• Language: English
• Published: Institute of Cytology and Genetics of Siberian Branch of the RAS 2021
• Subjects: премоторный вызванный потенциал; 5-HTTLPR polymorphism; personal anxiety; stop-signal paradigm; premotor evoked potential; полиморфизм 5-HTTLPR; личностная тревожность; парадигма стоп-сигнал; Sakha; Sakha Republic; Yakutia; Siberia
• Online Access: https://vavilov.elpub.ru/jour/article/view/3117; https://doi.org/10.18699/VJ21.066

The allelic polymorphism of the serotonin transporter’s gene 5-HTTLPR is considered as one of the factors determining an individual genetic predisposition to the development of a wide range of affective disorders, including depression. Many studies have shown that the climatic and social conditions...