Variability of cancer risk within an area: time to complement the incidence rate
The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European agestandardized incidence rates (ASRs) for ‘all sites excluding nonmelan...
Published in: | European Journal of Cancer Prevention |
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LIPPINCOTT WILLIAMS & WILKINS
2017
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Online Access: | https://publications.jrc.ec.europa.eu/repository/handle/JRC106207 https://doi.org/10.1097/CEJ.0000000000000389 |
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ftjrc:oai:publications.jrc.ec.europa.eu:JRC106207 2023-05-15T16:10:57+02:00 Variability of cancer risk within an area: time to complement the incidence rate CROCETTI Emanuele GIUSTI Francesco MARTOS JIMENEZ Maria Del Carmen RANDI Giorgia DYBA Tadeusz Artur BETTIO Manola 2017 Printed https://publications.jrc.ec.europa.eu/repository/handle/JRC106207 https://doi.org/10.1097/CEJ.0000000000000389 ENG eng LIPPINCOTT WILLIAMS & WILKINS JRC106207 2017 ftjrc https://doi.org/10.1097/CEJ.0000000000000389 2022-05-01T08:20:02Z The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European agestandardized incidence rates (ASRs) for ‘all sites excluding nonmelanoma skin cancer’, for men, in 2014, for Nordic countries as a whole, for each country (Denmark, Faroe Islands, Finland, Greenland, Iceland, Sweden and Norway) and for their regions, were retrieved from the Nordcan with corresponding standard errors SEs. We compared the ASR for Nordic countries versus single country and single country versus specific regions. The overlapping of 95% confidence intervals was used for ASRs comparisons. As a measure of variability, we computed the range between the highest and the lowest ASR within an area and the ratio between this range and the ASR of the overall area, r/R=(range/ASR)×100. The 95% confidence interval of the ASR for Nordic countries as a whole did not overlap those of the majority of the single countries; in fact, the r/R – which provides a clue for the amount of underlying geographical variability – was rather large (57.1%). Within countries, the variability was negligible in Iceland (r/R=9.6%), whereas the highest value was found in Sweden (37.1%). The ASR does not provide any information on underlying geographical variability. Therefore, its interpretation could be misleading. When data for subareas are available, the r/R, which is simple to compute and to understand, should be added to the ASR for providing more truthful information. JRC.F.1 - Health in Society Other/Unknown Material Faroe Islands Greenland Iceland Joint Research Centre, European Commission: JRC Publications Repository Faroe Islands Greenland Norway European Journal of Cancer Prevention 26 5 442 446 |
institution |
Open Polar |
collection |
Joint Research Centre, European Commission: JRC Publications Repository |
op_collection_id |
ftjrc |
language |
English |
description |
The aim of this study was to show that age-adjusted cancer incidence rates for an area may not be representative of the incidence in subareas. We propose a simple measure to show the amount of geographical variability. European agestandardized incidence rates (ASRs) for ‘all sites excluding nonmelanoma skin cancer’, for men, in 2014, for Nordic countries as a whole, for each country (Denmark, Faroe Islands, Finland, Greenland, Iceland, Sweden and Norway) and for their regions, were retrieved from the Nordcan with corresponding standard errors SEs. We compared the ASR for Nordic countries versus single country and single country versus specific regions. The overlapping of 95% confidence intervals was used for ASRs comparisons. As a measure of variability, we computed the range between the highest and the lowest ASR within an area and the ratio between this range and the ASR of the overall area, r/R=(range/ASR)×100. The 95% confidence interval of the ASR for Nordic countries as a whole did not overlap those of the majority of the single countries; in fact, the r/R – which provides a clue for the amount of underlying geographical variability – was rather large (57.1%). Within countries, the variability was negligible in Iceland (r/R=9.6%), whereas the highest value was found in Sweden (37.1%). The ASR does not provide any information on underlying geographical variability. Therefore, its interpretation could be misleading. When data for subareas are available, the r/R, which is simple to compute and to understand, should be added to the ASR for providing more truthful information. JRC.F.1 - Health in Society |
author |
CROCETTI Emanuele GIUSTI Francesco MARTOS JIMENEZ Maria Del Carmen RANDI Giorgia DYBA Tadeusz Artur BETTIO Manola |
spellingShingle |
CROCETTI Emanuele GIUSTI Francesco MARTOS JIMENEZ Maria Del Carmen RANDI Giorgia DYBA Tadeusz Artur BETTIO Manola Variability of cancer risk within an area: time to complement the incidence rate |
author_facet |
CROCETTI Emanuele GIUSTI Francesco MARTOS JIMENEZ Maria Del Carmen RANDI Giorgia DYBA Tadeusz Artur BETTIO Manola |
author_sort |
CROCETTI Emanuele |
title |
Variability of cancer risk within an area: time to complement the incidence rate |
title_short |
Variability of cancer risk within an area: time to complement the incidence rate |
title_full |
Variability of cancer risk within an area: time to complement the incidence rate |
title_fullStr |
Variability of cancer risk within an area: time to complement the incidence rate |
title_full_unstemmed |
Variability of cancer risk within an area: time to complement the incidence rate |
title_sort |
variability of cancer risk within an area: time to complement the incidence rate |
publisher |
LIPPINCOTT WILLIAMS & WILKINS |
publishDate |
2017 |
url |
https://publications.jrc.ec.europa.eu/repository/handle/JRC106207 https://doi.org/10.1097/CEJ.0000000000000389 |
geographic |
Faroe Islands Greenland Norway |
geographic_facet |
Faroe Islands Greenland Norway |
genre |
Faroe Islands Greenland Iceland |
genre_facet |
Faroe Islands Greenland Iceland |
op_relation |
JRC106207 |
op_doi |
https://doi.org/10.1097/CEJ.0000000000000389 |
container_title |
European Journal of Cancer Prevention |
container_volume |
26 |
container_issue |
5 |
container_start_page |
442 |
op_container_end_page |
446 |
_version_ |
1765996077392068608 |