VARIABILITY OF INTERLEUKIN 4 AND ITS RECEPTOR GENES IN NATIVE POPULATIONS OF SIBERIA
Genetic diversity of SNP markers of Interleukin 4 alpha and Interleukin 4 receptor genes was investigated in 4 populations of native Siberian ethnic groups (Buryat, Yakut, Ket and Khant). In the populations under study, except Khants, the close spectrum of allele frequencies and similar level of exp...
Main Authors: | , , , , , , , |
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Other Authors: | |
Format: | Article in Journal/Newspaper |
Language: | Russian |
Published: |
Publishing House «Genius Media» LLC
2015
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Subjects: | |
Online Access: | https://www.medgen-journal.ru/jour/article/view/49 https://doi.org/10.1234/XXXX-XXXX-2013-4-38-40 |
Summary: | Genetic diversity of SNP markers of Interleukin 4 alpha and Interleukin 4 receptor genes was investigated in 4 populations of native Siberian ethnic groups (Buryat, Yakut, Ket and Khant). In the populations under study, except Khants, the close spectrum of allele frequencies and similar level of expected heterozygosity were revealed and low level of genetic differentiation was found. Исследовано генетическое разнообразие популяций четырёх этнических групп коренного населения Сибири (буряты, якуты, кеты, ханты) по SNP-маркёрам генов интерлейкина 4 и α-цепи рецептора интерлейкина 4. В исследованных популяциях, за исключением хантов, выявлен близкий спектр частот аллелей, сходный уровень ожидаемой гетерозиготности и показана низкая степень генетической дифференциации популяций. |
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