A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING
We have gone through various papers describing the mutations in between them and associated disease in a rapid pace. The articles of previous studies show that there is a need to acquire knowledge of gene mutation causing diseases and its association. The need cannot be solved manually, but it has t...
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ftjijitr:oai:ojs.ijitr.com:article/1547 2023-05-15T16:01:49+02:00 A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING Krishna, A.Murali Jyothi, Dr. S. 2017-01-17 application/pdf http://www.ijitr.com/index.php/ojs/article/view/1547 eng eng International Journal of Innovative Technology and Research http://www.ijitr.com/index.php/ojs/article/view/1547/pdf http://www.ijitr.com/index.php/ojs/article/view/1547 To The Editor-in-Chief, IJITR 1. I understand that the Editor-in-Chief may transfer the Copyright to a publisher at his discretion. 2. The author(s) reserve(s) all proprietary rights such as patent rights and the right to use all or part of the article in future works of their own such as lectures, press releases, and reviews of textbooks. In the case of republication of the whole, part, or parts thereof, in periodicals or reprint publications by a third party, written permission must be obtained from the The Editor-in-Chief IJITR, or his designated publisher. 3. I am authorized to execute this transfer of copyright on behalf of all the authors of the article named above. 4. I hereby declare that the material being presented by me in this paper is our original work, and does not contain or include material taken from other copyrighted sources. Wherever such material has been included, it has been clearly indented or/and identified by quotation marks and due and proper acknowledgements given by citing the source at appropriate places. International Journal of Innovative Technology and Research; Vol 5, No 1 (2017): December - January 2017; 5536-5542 CSE Mutation;Extraction;NLP;Text Mining;Pubmed;Gene info:eu-repo/semantics/article Peer-reviewed Article info:eu-repo/semantics/publishedVersion 2017 ftjijitr 2022-04-10T20:32:46Z We have gone through various papers describing the mutations in between them and associated disease in a rapid pace. The articles of previous studies show that there is a need to acquire knowledge of gene mutation causing diseases and its association. The need cannot be solved manually, but it has to be automated, so our study is based to develop a framework which gathers information of disease association mutation for knowledge sharing to doctors and researchers. Our work is done using texting mining for extraction of disease causing mutation and its associated NLP from previous abstracts. Our proposed system extracts mutation causing gene using NLP.DMLtool consists of modules of NLP that process text input using semantic and synaptic patterns to gain disease mutation. DML developed gives recall and precision high with F-score 0.87 , 0.89 and 0.91, which were evaluated on 3 various datasets related to associated disease mutations. In DML we used a special module which extracts mentioned mutation and its gene text associated with it. Various types of datasets have been evaluated on our framework and its performance has been check with performance metric.The obtained results shows better performance compared to the existing on association of disease-mutation and also solves problems of low precision and their approaches.LMA is applied to large data sets of different type of abstracts in Pubmed, it extracts associated disease-mutations and its related information of patients, population of data and its type size. The gained result from our work is stored in a database, which can be acquired by query processing. In our work we conclude that using text mining method, we can increase high throughput, this gives potential to the research and also assist the research in identifying mutation causing disease and it’s associated with. Article in Journal/Newspaper DML International Journal of Innovative Technology and Research (IJITR) |
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Open Polar |
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International Journal of Innovative Technology and Research (IJITR) |
op_collection_id |
ftjijitr |
language |
English |
topic |
CSE Mutation;Extraction;NLP;Text Mining;Pubmed;Gene |
spellingShingle |
CSE Mutation;Extraction;NLP;Text Mining;Pubmed;Gene Krishna, A.Murali Jyothi, Dr. S. A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
topic_facet |
CSE Mutation;Extraction;NLP;Text Mining;Pubmed;Gene |
description |
We have gone through various papers describing the mutations in between them and associated disease in a rapid pace. The articles of previous studies show that there is a need to acquire knowledge of gene mutation causing diseases and its association. The need cannot be solved manually, but it has to be automated, so our study is based to develop a framework which gathers information of disease association mutation for knowledge sharing to doctors and researchers. Our work is done using texting mining for extraction of disease causing mutation and its associated NLP from previous abstracts. Our proposed system extracts mutation causing gene using NLP.DMLtool consists of modules of NLP that process text input using semantic and synaptic patterns to gain disease mutation. DML developed gives recall and precision high with F-score 0.87 , 0.89 and 0.91, which were evaluated on 3 various datasets related to associated disease mutations. In DML we used a special module which extracts mentioned mutation and its gene text associated with it. Various types of datasets have been evaluated on our framework and its performance has been check with performance metric.The obtained results shows better performance compared to the existing on association of disease-mutation and also solves problems of low precision and their approaches.LMA is applied to large data sets of different type of abstracts in Pubmed, it extracts associated disease-mutations and its related information of patients, population of data and its type size. The gained result from our work is stored in a database, which can be acquired by query processing. In our work we conclude that using text mining method, we can increase high throughput, this gives potential to the research and also assist the research in identifying mutation causing disease and it’s associated with. |
format |
Article in Journal/Newspaper |
author |
Krishna, A.Murali Jyothi, Dr. S. |
author_facet |
Krishna, A.Murali Jyothi, Dr. S. |
author_sort |
Krishna, A.Murali |
title |
A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
title_short |
A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
title_full |
A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
title_fullStr |
A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
title_full_unstemmed |
A FRAME WORK FOR IDENTIFICATION OF RELATIONSHIP BETWEEN GENE AND DISEASE CAUSING MUTATION USING BIOLOGICAL TEXT MINING |
title_sort |
frame work for identification of relationship between gene and disease causing mutation using biological text mining |
publisher |
International Journal of Innovative Technology and Research |
publishDate |
2017 |
url |
http://www.ijitr.com/index.php/ojs/article/view/1547 |
genre |
DML |
genre_facet |
DML |
op_source |
International Journal of Innovative Technology and Research; Vol 5, No 1 (2017): December - January 2017; 5536-5542 |
op_relation |
http://www.ijitr.com/index.php/ojs/article/view/1547/pdf http://www.ijitr.com/index.php/ojs/article/view/1547 |
op_rights |
To The Editor-in-Chief, IJITR 1. I understand that the Editor-in-Chief may transfer the Copyright to a publisher at his discretion. 2. The author(s) reserve(s) all proprietary rights such as patent rights and the right to use all or part of the article in future works of their own such as lectures, press releases, and reviews of textbooks. In the case of republication of the whole, part, or parts thereof, in periodicals or reprint publications by a third party, written permission must be obtained from the The Editor-in-Chief IJITR, or his designated publisher. 3. I am authorized to execute this transfer of copyright on behalf of all the authors of the article named above. 4. I hereby declare that the material being presented by me in this paper is our original work, and does not contain or include material taken from other copyrighted sources. Wherever such material has been included, it has been clearly indented or/and identified by quotation marks and due and proper acknowledgements given by citing the source at appropriate places. |
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