Highly Efficient Lipase-Catalyzed Kinetic Resolution of Chiral Amines

The lipase Candida antarctica catalyzes the enantioselective acetylation of chiral primary amines, kinetic resolution leading to an enantiomeric excess (ee) of 90–98%.

Bibliographic Details
Published in:CHIMIA
Main Authors: Reetz, Manfred T., Dreisbach, Claus
Format: Article in Journal/Newspaper
Language:English
Published: Swiss Chemical Society 1994
Subjects:
Antarc*
Antarctica
Online Access:https://www.chimia.ch/chimia/article/view/1994_570
https://doi.org/10.2533/chimia.1994.570
Description
Summary:The lipase Candida antarctica catalyzes the enantioselective acetylation of chiral primary amines, kinetic resolution leading to an enantiomeric excess (ee) of 90–98%.

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