Transcriptomic profiling of adaptive responses to ocean acidification
Some populations of marine organisms appear to have inherent tolerance or the capacity for acclimation to stressful environmental conditions, including those associated with climate change. Sydney rock oysters from the B2 breeding line exhibit resilience to ocean acidification (OA) at the physiologi...
Published in: | Molecular Ecology |
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Blackwell Publishing
2017
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Online Access: | https://researchonline.jcu.edu.au/51710/1/Jones%20et%20al.pdf |
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ftjamescook:oai:researchonline.jcu.edu.au:51710 2024-02-11T10:07:28+01:00 Transcriptomic profiling of adaptive responses to ocean acidification Goncalves, Priscila Jones, David B. Thompson, Emma L. Parker, Laura M. Ross, Pauline M. Raftos, David A. 2017-11 application/pdf https://researchonline.jcu.edu.au/51710/1/Jones%20et%20al.pdf unknown Blackwell Publishing http://dx.doi.org/10.1111/mec.14333 https://researchonline.jcu.edu.au/51710/ https://researchonline.jcu.edu.au/51710/1/Jones%20et%20al.pdf Goncalves, Priscila, Jones, David B., Thompson, Emma L., Parker, Laura M., Ross, Pauline M., and Raftos, David A. (2017) Transcriptomic profiling of adaptive responses to ocean acidification. Molecular Ecology, 26 (21). pp. 5974-5988. restricted Article PeerReviewed 2017 ftjamescook https://doi.org/10.1111/mec.14333 2024-01-22T23:41:07Z Some populations of marine organisms appear to have inherent tolerance or the capacity for acclimation to stressful environmental conditions, including those associated with climate change. Sydney rock oysters from the B2 breeding line exhibit resilience to ocean acidification (OA) at the physiological level. To understand the molecular basis of this physiological resilience, we analysed the gill transcriptome of B2 oysters that had been exposed to near-future projected ocean pH over two consecutive generations. Our results suggest that the distinctive performance of B2 oysters in the face of OA is mediated by the selective expression of genes involved in multiple cellular processes. Subsequent high-throughput qPCR revealed that some of these transcriptional changes are exclusive to B2 oysters and so may be associated with their resilience to OA. The intracellular processes mediated by the differentially abundant genes primarily involve control of the cell cycle and maintenance of cellular homeostasis. These changes may enable B2 oysters to prevent apoptosis resulting from oxidative damage or to alleviate the effects of apoptosis through regulation of the cell cycle. Comparative analysis of the OA conditioning effects across sequential generations supported the contention that B2 and wild-type oysters have different trajectories of changing gene expression and responding to OA. Our findings reveal the broad set of molecular processes underlying transgenerational conditioning and potential resilience to OA in a marine calcifier. Identifying the mechanisms of stress resilience can uncover the intracellular basis for these organisms to survive and thrive in a rapidly changing ocean. Article in Journal/Newspaper Ocean acidification James Cook University, Australia: ResearchOnline@JCU Molecular Ecology 26 21 5974 5988 |
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James Cook University, Australia: ResearchOnline@JCU |
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ftjamescook |
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description |
Some populations of marine organisms appear to have inherent tolerance or the capacity for acclimation to stressful environmental conditions, including those associated with climate change. Sydney rock oysters from the B2 breeding line exhibit resilience to ocean acidification (OA) at the physiological level. To understand the molecular basis of this physiological resilience, we analysed the gill transcriptome of B2 oysters that had been exposed to near-future projected ocean pH over two consecutive generations. Our results suggest that the distinctive performance of B2 oysters in the face of OA is mediated by the selective expression of genes involved in multiple cellular processes. Subsequent high-throughput qPCR revealed that some of these transcriptional changes are exclusive to B2 oysters and so may be associated with their resilience to OA. The intracellular processes mediated by the differentially abundant genes primarily involve control of the cell cycle and maintenance of cellular homeostasis. These changes may enable B2 oysters to prevent apoptosis resulting from oxidative damage or to alleviate the effects of apoptosis through regulation of the cell cycle. Comparative analysis of the OA conditioning effects across sequential generations supported the contention that B2 and wild-type oysters have different trajectories of changing gene expression and responding to OA. Our findings reveal the broad set of molecular processes underlying transgenerational conditioning and potential resilience to OA in a marine calcifier. Identifying the mechanisms of stress resilience can uncover the intracellular basis for these organisms to survive and thrive in a rapidly changing ocean. |
format |
Article in Journal/Newspaper |
author |
Goncalves, Priscila Jones, David B. Thompson, Emma L. Parker, Laura M. Ross, Pauline M. Raftos, David A. |
spellingShingle |
Goncalves, Priscila Jones, David B. Thompson, Emma L. Parker, Laura M. Ross, Pauline M. Raftos, David A. Transcriptomic profiling of adaptive responses to ocean acidification |
author_facet |
Goncalves, Priscila Jones, David B. Thompson, Emma L. Parker, Laura M. Ross, Pauline M. Raftos, David A. |
author_sort |
Goncalves, Priscila |
title |
Transcriptomic profiling of adaptive responses to ocean acidification |
title_short |
Transcriptomic profiling of adaptive responses to ocean acidification |
title_full |
Transcriptomic profiling of adaptive responses to ocean acidification |
title_fullStr |
Transcriptomic profiling of adaptive responses to ocean acidification |
title_full_unstemmed |
Transcriptomic profiling of adaptive responses to ocean acidification |
title_sort |
transcriptomic profiling of adaptive responses to ocean acidification |
publisher |
Blackwell Publishing |
publishDate |
2017 |
url |
https://researchonline.jcu.edu.au/51710/1/Jones%20et%20al.pdf |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_relation |
http://dx.doi.org/10.1111/mec.14333 https://researchonline.jcu.edu.au/51710/ https://researchonline.jcu.edu.au/51710/1/Jones%20et%20al.pdf Goncalves, Priscila, Jones, David B., Thompson, Emma L., Parker, Laura M., Ross, Pauline M., and Raftos, David A. (2017) Transcriptomic profiling of adaptive responses to ocean acidification. Molecular Ecology, 26 (21). pp. 5974-5988. |
op_rights |
restricted |
op_doi |
https://doi.org/10.1111/mec.14333 |
container_title |
Molecular Ecology |
container_volume |
26 |
container_issue |
21 |
container_start_page |
5974 |
op_container_end_page |
5988 |
_version_ |
1790606040124882944 |