North Asian population relationships in a global context
Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia mic...
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ftistanbuluniv:oai:http://acikerisim.istanbul.edu.tr:20.500.12627/185308 2023-05-15T17:02:52+02:00 North Asian population relationships in a global context Speed, William C. Pakstis, Andrew J. Cherni, Lotfi Murtha, Michael Kidd, Judith R. Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos Gurkan, Cemal Bulbul, Ozlem Yale University , , 3422259 2022 https://hdl.handle.net/20.500.12627/185308 https://avesis.istanbul.edu.tr/api/publication/f0212473-8e79-448f-a335-a538912f2ae9/file https://doi.org/10.1038/s41598-022-10706-x eng eng SCIENTIFIC REPORTS Kidd K. K. , Evsanaa B., Togtokh A., Brissenden J. E. , Roscoe J. M. , Dogan M., Neophytou P., Gurkan C., Bulbul O., Cherni L., et al., "North Asian population relationships in a global context", SCIENTIFIC REPORTS, cilt.12, sa.1, 2022 2045-2322 vv_1032021 av_f0212473-8e79-448f-a335-a538912f2ae9 http://hdl.handle.net/20.500.12627/185308 https://avesis.istanbul.edu.tr/api/publication/f0212473-8e79-448f-a335-a538912f2ae9/file https://doi.org/10.1038/s41598-022-10706-x 12 1 Temel Bilimler Doğa Bilimleri Genel Multidisciplinary Temel Bilimler (SCI) ÇOK DİSİPLİNLİ BİLİMLER Makale 2022 ftistanbuluniv https://doi.org/20.500.12627/185308 https://doi.org/10.1038/s41598-022-10706-x 2022-08-10T13:04:40Z Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia microhaplotype data. We combined genotypes from our laboratory on 58 microhaplotypes, distributed across 18 autosomes, on 3945 individuals from 75 populations with corresponding data extracted for 26 populations from the Thousand Genomes consortium and for 22 populations from the GenomeAsia 100 K project. A total of 7107 individuals in 122 total populations are analyzed using STRUCTURE, Principal Component Analysis, and phylogenetic tree analyses. North Asia populations sampled in Mongolia include: Buryats, Mongolians, Altai Kazakhs, and Tsaatans. Available Siberians include samples of Yakut, Khanty, and Komi Zyriane. Analyses of all 122 populations confirm many known relationships and show that most populations from North Asia form a cluster distinct from all other groups. Refinement of analyses on smaller subsets of populations reinforces the distinctiveness of North Asia and shows that the North Asia cluster identifies a region that is ancestral to Native Americans. Article in Journal/Newspaper khanty İstanbul Üniversitesi Açık Erişim Sistemi Scientific Reports 12 1 |
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İstanbul Üniversitesi Açık Erişim Sistemi |
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ftistanbuluniv |
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English |
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Temel Bilimler Doğa Bilimleri Genel Multidisciplinary Temel Bilimler (SCI) ÇOK DİSİPLİNLİ BİLİMLER |
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Temel Bilimler Doğa Bilimleri Genel Multidisciplinary Temel Bilimler (SCI) ÇOK DİSİPLİNLİ BİLİMLER Speed, William C. Pakstis, Andrew J. Cherni, Lotfi Murtha, Michael Kidd, Judith R. Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos Gurkan, Cemal Bulbul, Ozlem North Asian population relationships in a global context |
topic_facet |
Temel Bilimler Doğa Bilimleri Genel Multidisciplinary Temel Bilimler (SCI) ÇOK DİSİPLİNLİ BİLİMLER |
description |
Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia microhaplotype data. We combined genotypes from our laboratory on 58 microhaplotypes, distributed across 18 autosomes, on 3945 individuals from 75 populations with corresponding data extracted for 26 populations from the Thousand Genomes consortium and for 22 populations from the GenomeAsia 100 K project. A total of 7107 individuals in 122 total populations are analyzed using STRUCTURE, Principal Component Analysis, and phylogenetic tree analyses. North Asia populations sampled in Mongolia include: Buryats, Mongolians, Altai Kazakhs, and Tsaatans. Available Siberians include samples of Yakut, Khanty, and Komi Zyriane. Analyses of all 122 populations confirm many known relationships and show that most populations from North Asia form a cluster distinct from all other groups. Refinement of analyses on smaller subsets of populations reinforces the distinctiveness of North Asia and shows that the North Asia cluster identifies a region that is ancestral to Native Americans. |
author2 |
Yale University , , 3422259 |
format |
Article in Journal/Newspaper |
author |
Speed, William C. Pakstis, Andrew J. Cherni, Lotfi Murtha, Michael Kidd, Judith R. Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos Gurkan, Cemal Bulbul, Ozlem |
author_facet |
Speed, William C. Pakstis, Andrew J. Cherni, Lotfi Murtha, Michael Kidd, Judith R. Kidd, Kenneth K. Evsanaa, Baigalmaa Togtokh, Ariunaa Brissenden, Jane E. Roscoe, Janet M. Dogan, Mustafa Neophytou, Pavlos Gurkan, Cemal Bulbul, Ozlem |
author_sort |
Speed, William C. |
title |
North Asian population relationships in a global context |
title_short |
North Asian population relationships in a global context |
title_full |
North Asian population relationships in a global context |
title_fullStr |
North Asian population relationships in a global context |
title_full_unstemmed |
North Asian population relationships in a global context |
title_sort |
north asian population relationships in a global context |
publishDate |
2022 |
url |
https://hdl.handle.net/20.500.12627/185308 https://avesis.istanbul.edu.tr/api/publication/f0212473-8e79-448f-a335-a538912f2ae9/file https://doi.org/10.1038/s41598-022-10706-x |
genre |
khanty |
genre_facet |
khanty |
op_relation |
SCIENTIFIC REPORTS Kidd K. K. , Evsanaa B., Togtokh A., Brissenden J. E. , Roscoe J. M. , Dogan M., Neophytou P., Gurkan C., Bulbul O., Cherni L., et al., "North Asian population relationships in a global context", SCIENTIFIC REPORTS, cilt.12, sa.1, 2022 2045-2322 vv_1032021 av_f0212473-8e79-448f-a335-a538912f2ae9 http://hdl.handle.net/20.500.12627/185308 https://avesis.istanbul.edu.tr/api/publication/f0212473-8e79-448f-a335-a538912f2ae9/file https://doi.org/10.1038/s41598-022-10706-x 12 1 |
op_doi |
https://doi.org/20.500.12627/185308 https://doi.org/10.1038/s41598-022-10706-x |
container_title |
Scientific Reports |
container_volume |
12 |
container_issue |
1 |
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1766056556321832960 |