CanisOme — The protein signatures of Canis lupus familiaris diseases
Although the applications of Proteomics in Human Biomedicine have been explored for some time now, in animal and veterinary research, the potential of this resource has just started to be explored, especially when companion animal health is considered. In the last years, knowledge on the Canis lupus...
Published in: | Journal of Proteomics |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2016
|
Subjects: | |
Online Access: | http://hdl.handle.net/10400.19/3140 https://doi.org/10.1016/j.jprot.2016.01.005 |
id |
ftipviseu:oai:repositorio.ipv.pt:10400.19/3140 |
---|---|
record_format |
openpolar |
spelling |
ftipviseu:oai:repositorio.ipv.pt:10400.19/3140 2023-05-15T15:49:28+02:00 CanisOme — The protein signatures of Canis lupus familiaris diseases Fernandes, Mónica Rosa, Nuno Esteves, Eduardo Correia, Maria José Arrais, Joel Ribeiro, Paulo Vala, Helena Barros, Marlene 2016-04-05T16:02:01Z http://hdl.handle.net/10400.19/3140 https://doi.org/10.1016/j.jprot.2016.01.005 eng eng Work developed in the SalivaTec laboratory was financed by Mais Centro — Programa Operacional Regional do Centro (CENTRO-07- CT62-FEDER-005,004) under the National Strategic Reference Frame- work and the European Regional Development Fund http://hdl.handle.net/10400.19/3140 doi:10.1016/j.jprot.2016.01.005 restrictedAccess CanisOme Canis DiseasOme Canis biomarkers Canis Leishmaniosis article 2016 ftipviseu https://doi.org/10.1016/j.jprot.2016.01.005 2022-01-05T01:05:47Z Although the applications of Proteomics in Human Biomedicine have been explored for some time now, in animal and veterinary research, the potential of this resource has just started to be explored, especially when companion animal health is considered. In the last years, knowledge on the Canis lupus familiaris proteome has been accumulating in the literature and a resource compiling all this information and critically reviewing it was lacking. This article presents such a resource for the first time. CanisOme is a database of all proteins identified in Canis lupus familiaris tissues, either in health or in disease, annotated with information on the proteins present on the sample and on the donors. This database reunites information on 549 proteins, associated with 63 dog diseases and 33 dog breeds. Examples of how this information may be used to produce new hypothesis on disease mechanisms is presented both through the functional analysis of the proteins quantified in canine cutaneous mast cell tumors and through the study of the interactome of C. lupus familiaris and Leishmania infantum. Therefore, the usefulness of CanisOme for researchers looking for protein biomarkers in dogs and interested in a comprehensive analysis of disease mechanisms is demonstrated. Article in Journal/Newspaper Canis lupus Repositório do Instituto Politécnico de Viseu Journal of Proteomics 136 193 201 |
institution |
Open Polar |
collection |
Repositório do Instituto Politécnico de Viseu |
op_collection_id |
ftipviseu |
language |
English |
topic |
CanisOme Canis DiseasOme Canis biomarkers Canis Leishmaniosis |
spellingShingle |
CanisOme Canis DiseasOme Canis biomarkers Canis Leishmaniosis Fernandes, Mónica Rosa, Nuno Esteves, Eduardo Correia, Maria José Arrais, Joel Ribeiro, Paulo Vala, Helena Barros, Marlene CanisOme — The protein signatures of Canis lupus familiaris diseases |
topic_facet |
CanisOme Canis DiseasOme Canis biomarkers Canis Leishmaniosis |
description |
Although the applications of Proteomics in Human Biomedicine have been explored for some time now, in animal and veterinary research, the potential of this resource has just started to be explored, especially when companion animal health is considered. In the last years, knowledge on the Canis lupus familiaris proteome has been accumulating in the literature and a resource compiling all this information and critically reviewing it was lacking. This article presents such a resource for the first time. CanisOme is a database of all proteins identified in Canis lupus familiaris tissues, either in health or in disease, annotated with information on the proteins present on the sample and on the donors. This database reunites information on 549 proteins, associated with 63 dog diseases and 33 dog breeds. Examples of how this information may be used to produce new hypothesis on disease mechanisms is presented both through the functional analysis of the proteins quantified in canine cutaneous mast cell tumors and through the study of the interactome of C. lupus familiaris and Leishmania infantum. Therefore, the usefulness of CanisOme for researchers looking for protein biomarkers in dogs and interested in a comprehensive analysis of disease mechanisms is demonstrated. |
format |
Article in Journal/Newspaper |
author |
Fernandes, Mónica Rosa, Nuno Esteves, Eduardo Correia, Maria José Arrais, Joel Ribeiro, Paulo Vala, Helena Barros, Marlene |
author_facet |
Fernandes, Mónica Rosa, Nuno Esteves, Eduardo Correia, Maria José Arrais, Joel Ribeiro, Paulo Vala, Helena Barros, Marlene |
author_sort |
Fernandes, Mónica |
title |
CanisOme — The protein signatures of Canis lupus familiaris diseases |
title_short |
CanisOme — The protein signatures of Canis lupus familiaris diseases |
title_full |
CanisOme — The protein signatures of Canis lupus familiaris diseases |
title_fullStr |
CanisOme — The protein signatures of Canis lupus familiaris diseases |
title_full_unstemmed |
CanisOme — The protein signatures of Canis lupus familiaris diseases |
title_sort |
canisome — the protein signatures of canis lupus familiaris diseases |
publishDate |
2016 |
url |
http://hdl.handle.net/10400.19/3140 https://doi.org/10.1016/j.jprot.2016.01.005 |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_relation |
Work developed in the SalivaTec laboratory was financed by Mais Centro — Programa Operacional Regional do Centro (CENTRO-07- CT62-FEDER-005,004) under the National Strategic Reference Frame- work and the European Regional Development Fund http://hdl.handle.net/10400.19/3140 doi:10.1016/j.jprot.2016.01.005 |
op_rights |
restrictedAccess |
op_doi |
https://doi.org/10.1016/j.jprot.2016.01.005 |
container_title |
Journal of Proteomics |
container_volume |
136 |
container_start_page |
193 |
op_container_end_page |
201 |
_version_ |
1766384493786038272 |