Patterns of homozygosity in insular and continental goat breeds
Background: Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds...
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ftiowastateuniv:oai:lib.dr.iastate.edu:ans_pubs-1453 2023-05-15T16:48:42+02:00 Patterns of homozygosity in insular and continental goat breeds Cardoso, Taina F. Amills, Marcel Bertolini, Francesca Rothschild, Max Marras, Gabriele Boink, Geert Jordana, Jordi Capote, Juan Carolan, Sean Hallsson, Jón H. Kantanen, Juha Pons, Agueda Lenstra, Johannes A. The AdaptMap Consortium 2018-11-19T08:00:00Z application/pdf https://lib.dr.iastate.edu/ans_pubs/453 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1453&context=ans_pubs en eng Iowa State University Digital Repository https://lib.dr.iastate.edu/ans_pubs/453 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1453&context=ans_pubs http://creativecommons.org/licenses/by/4.0/ CC-BY Animal Science Publications Agriculture Animal Sciences Genetics and Genomics Geography Sheep and Goat Science text 2018 ftiowastateuniv 2021-08-21T22:45:06Z Background: Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Results: Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and FROH values (P value < 0.05). Goats from Mediterranean islands represent a more complex case because certain populations displayed a significantly increased level of homozygosity (e.g. Girgentana) and others did not (e.g. Corse and Sarda). Correlations of number and total length of ROH for insular goat populations with the distance between islands and the nearest continental locations revealed an effect of extremely long distances on the patterns of homozygosity. Conclusions: These results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management. Text Iceland Digital Repository @ Iowa State University |
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Open Polar |
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Digital Repository @ Iowa State University |
op_collection_id |
ftiowastateuniv |
language |
English |
topic |
Agriculture Animal Sciences Genetics and Genomics Geography Sheep and Goat Science |
spellingShingle |
Agriculture Animal Sciences Genetics and Genomics Geography Sheep and Goat Science Cardoso, Taina F. Amills, Marcel Bertolini, Francesca Rothschild, Max Marras, Gabriele Boink, Geert Jordana, Jordi Capote, Juan Carolan, Sean Hallsson, Jón H. Kantanen, Juha Pons, Agueda Lenstra, Johannes A. The AdaptMap Consortium Patterns of homozygosity in insular and continental goat breeds |
topic_facet |
Agriculture Animal Sciences Genetics and Genomics Geography Sheep and Goat Science |
description |
Background: Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Results: Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and FROH values (P value < 0.05). Goats from Mediterranean islands represent a more complex case because certain populations displayed a significantly increased level of homozygosity (e.g. Girgentana) and others did not (e.g. Corse and Sarda). Correlations of number and total length of ROH for insular goat populations with the distance between islands and the nearest continental locations revealed an effect of extremely long distances on the patterns of homozygosity. Conclusions: These results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management. |
format |
Text |
author |
Cardoso, Taina F. Amills, Marcel Bertolini, Francesca Rothschild, Max Marras, Gabriele Boink, Geert Jordana, Jordi Capote, Juan Carolan, Sean Hallsson, Jón H. Kantanen, Juha Pons, Agueda Lenstra, Johannes A. The AdaptMap Consortium |
author_facet |
Cardoso, Taina F. Amills, Marcel Bertolini, Francesca Rothschild, Max Marras, Gabriele Boink, Geert Jordana, Jordi Capote, Juan Carolan, Sean Hallsson, Jón H. Kantanen, Juha Pons, Agueda Lenstra, Johannes A. The AdaptMap Consortium |
author_sort |
Cardoso, Taina F. |
title |
Patterns of homozygosity in insular and continental goat breeds |
title_short |
Patterns of homozygosity in insular and continental goat breeds |
title_full |
Patterns of homozygosity in insular and continental goat breeds |
title_fullStr |
Patterns of homozygosity in insular and continental goat breeds |
title_full_unstemmed |
Patterns of homozygosity in insular and continental goat breeds |
title_sort |
patterns of homozygosity in insular and continental goat breeds |
publisher |
Iowa State University Digital Repository |
publishDate |
2018 |
url |
https://lib.dr.iastate.edu/ans_pubs/453 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1453&context=ans_pubs |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Animal Science Publications |
op_relation |
https://lib.dr.iastate.edu/ans_pubs/453 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1453&context=ans_pubs |
op_rights |
http://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
_version_ |
1766038775623843840 |