Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog
A survey was performed to determine the number of Newfoundlands that were seen at the Iowa State University College of Veterinary Medicine (ISUCVM) for cranial cruciate ligament disease (CCLD) from January, 1996 through December, 2002. Of the 163 Newfoundlands seen at the ISU-CVM, 22% were diagnosed...
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ftiowastateuniv:oai:lib.dr.iastate.edu:ans_air-1129 2023-05-15T17:22:05+02:00 Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog Wilke, Vicki L. Kinghorn, Brian P. Conzemius, Mike G. Rothschild, Max F. 2004-01-01T08:00:00Z application/pdf https://lib.dr.iastate.edu/ans_air/vol650/iss1/129 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1129&context=ans_air en eng Iowa State University Digital Repository https://lib.dr.iastate.edu/ans_air/vol650/iss1/129 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1129&context=ans_air Animal Industry Report ASL R1970 Agriculture Animal Sciences text 2004 ftiowastateuniv 2018-11-26T03:17:13Z A survey was performed to determine the number of Newfoundlands that were seen at the Iowa State University College of Veterinary Medicine (ISUCVM) for cranial cruciate ligament disease (CCLD) from January, 1996 through December, 2002. Of the 163 Newfoundlands seen at the ISU-CVM, 22% were diagnosed with CCLD. Further study of Newfoundlands was performed to collect pedigrees and ascertain whether or not individuals that were affected with CCLD or not were related. This information was used to determine the level of inbreeding, and the pattern of inheritance (i.e. recessive, sex-linked) for CCLD. This study found a recessive pattern of inheritance with partial penetrance of 59%. Therefore a dog has a 59% chance of showing signs of the disease when it has the recessive genotype. Text Newfoundland Digital Repository @ Iowa State University |
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Digital Repository @ Iowa State University |
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ftiowastateuniv |
language |
English |
topic |
ASL R1970 Agriculture Animal Sciences |
spellingShingle |
ASL R1970 Agriculture Animal Sciences Wilke, Vicki L. Kinghorn, Brian P. Conzemius, Mike G. Rothschild, Max F. Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
topic_facet |
ASL R1970 Agriculture Animal Sciences |
description |
A survey was performed to determine the number of Newfoundlands that were seen at the Iowa State University College of Veterinary Medicine (ISUCVM) for cranial cruciate ligament disease (CCLD) from January, 1996 through December, 2002. Of the 163 Newfoundlands seen at the ISU-CVM, 22% were diagnosed with CCLD. Further study of Newfoundlands was performed to collect pedigrees and ascertain whether or not individuals that were affected with CCLD or not were related. This information was used to determine the level of inbreeding, and the pattern of inheritance (i.e. recessive, sex-linked) for CCLD. This study found a recessive pattern of inheritance with partial penetrance of 59%. Therefore a dog has a 59% chance of showing signs of the disease when it has the recessive genotype. |
format |
Text |
author |
Wilke, Vicki L. Kinghorn, Brian P. Conzemius, Mike G. Rothschild, Max F. |
author_facet |
Wilke, Vicki L. Kinghorn, Brian P. Conzemius, Mike G. Rothschild, Max F. |
author_sort |
Wilke, Vicki L. |
title |
Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
title_short |
Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
title_full |
Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
title_fullStr |
Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
title_full_unstemmed |
Determining the Genetic Basis for Knee Disease in the Newfoundland Breed of Dog |
title_sort |
determining the genetic basis for knee disease in the newfoundland breed of dog |
publisher |
Iowa State University Digital Repository |
publishDate |
2004 |
url |
https://lib.dr.iastate.edu/ans_air/vol650/iss1/129 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1129&context=ans_air |
genre |
Newfoundland |
genre_facet |
Newfoundland |
op_source |
Animal Industry Report |
op_relation |
https://lib.dr.iastate.edu/ans_air/vol650/iss1/129 https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1129&context=ans_air |
_version_ |
1766108376406687744 |