Glycoglycerolipids From Sargassum vulgare as Potential Antifouling Agents

• Published in: Frontiers in Marine Science
• Main Authors: Plouguerne, Erwan, Souza, Lauro M., De, Sassaki, Guilherme L., Hellio, Claire, Trepos, Rozenn, Gama, Bernardo A. P., Da, Crespo Pereira, Renato, Barreto-Bergter, Eliana
• Other Authors: Fluminense Federal University Niterói, Universidade Federal do Paraná (UFPR), Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR), Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM), Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Universidade Federal do Rio de Janeiro Brasil = Federal University of Rio de Janeiro Brazil = Université fédérale de Rio de Janeiro Brésil (UFRJ)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2020
• Subjects: ACL; macroalgae; growth; antifouling; marine; microfouling; crassostrea-gigas; sediments; defense; biocides; copper; glycoglycerolipids; metals; Sargassum vulgare; toxicities; [SDE.BE]Environmental Sciences/Biodiversity and Ecology; Crassostrea gigas
• Online Access: https://hal.science/hal-03010378; https://hal.science/hal-03010378/document; https://hal.science/hal-03010378/file/Plouguerne_etal_FiMS_2020.pdf; https://doi.org/10.3389/fmars.2020.00116

WOS:000519752500001 International audience Unraveling new environmentally friendly antifouling (AF) agents is one of the major quests currently facing marine biotechnology. Marine macroalgae represent a rich source of new compounds with promising biological properties, including AF activity, but most of the macroalgal compounds studied to date are terpenoids or polyphenolics. The aim of this work was to investigate the possible AF role played by a usually neglected class of marine natural products: glycolipids (monogalactosyldiacylglycerols - MGDG, digalactosyldiacylglycerols - DGDG and sulfoquinovosyldiacylglycerols - SQDG) isolated from the Phaeophyceae Sargassum vulgare collected along the coast of south-eastern Brazil. Among the 18 extracts, fractions and sub-fractions tested, 3 subfractions demonstrated particularly promising AF activity toward the growth inhibition of marine bacteria and microalgae: F3III117, F4II70a, and F4II70b. The main compounds present in these fractions were identified as MGDG, DGDG, and SQDG, respectively. These results highlight the potential of glycoglycerolipids from S. vulgare as new promising antifouling agents.