Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages
International audience Background: In France, two main diseases threaten Pacific oyster production. Since 2008, Crassostrea gigas spat have suffered massive losses due to the ostreid herpesvirus OsHV-1, and since 2012, significant mortalities in commercial-size adults have been related to infection...
Published in: | Genetics Selection Evolution |
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Main Authors: | , , , , , |
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Format: | Article in Journal/Newspaper |
Language: | English |
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HAL CCSD
2017
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Online Access: | https://hal.science/hal-01479152 https://hal.science/hal-01479152/document https://hal.science/hal-01479152/file/12711_2017_Article_297.pdf https://doi.org/10.1186/s12711-017-0297-2 |
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openpolar |
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Open Polar |
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Institut national des sciences de l'Univers: HAL-INSU |
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English |
topic |
SELECTION ACL OSTREID HERPESVIRUS-1 INFECTION DISEASE RESISTANCE SUMMER MORTALITY HORIZONTAL TRANSMISSION PORTUGUESE OYSTER HERPES-VIRUS RISK-FACTORS FRANCE SPAT [SDV]Life Sciences [q-bio] [SDE.BE]Environmental Sciences/Biodiversity and Ecology |
spellingShingle |
SELECTION ACL OSTREID HERPESVIRUS-1 INFECTION DISEASE RESISTANCE SUMMER MORTALITY HORIZONTAL TRANSMISSION PORTUGUESE OYSTER HERPES-VIRUS RISK-FACTORS FRANCE SPAT [SDV]Life Sciences [q-bio] [SDE.BE]Environmental Sciences/Biodiversity and Ecology Azéma, Patrick Lamy, Jean-Baptiste Boudry, Pierre Renault, Tristan Travers, Marie-Agnès Dégremont, Lionel Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
topic_facet |
SELECTION ACL OSTREID HERPESVIRUS-1 INFECTION DISEASE RESISTANCE SUMMER MORTALITY HORIZONTAL TRANSMISSION PORTUGUESE OYSTER HERPES-VIRUS RISK-FACTORS FRANCE SPAT [SDV]Life Sciences [q-bio] [SDE.BE]Environmental Sciences/Biodiversity and Ecology |
description |
International audience Background: In France, two main diseases threaten Pacific oyster production. Since 2008, Crassostrea gigas spat have suffered massive losses due to the ostreid herpesvirus OsHV-1, and since 2012, significant mortalities in commercial-size adults have been related to infection by the bacterium Vibrio aestuarianus. The genetic basis for resistance to V. aestuarianus and OsHV-1 and the nature of the genetic correlation between these two traits were investigated by using 20 half-sib sire families, each containing two full-sib families. For each disease, controlled infectious challenges were conducted using naïve oysters that were 3 to 26 months old. In addition, siblings were tested under field, pond and raceway conditions to determine whether laboratory trials reflected mortality events that occur in the oyster industry.Results: First, we estimated the genetic basis of resistance to V. aestuarianus in C. gigas. Susceptibility to the infection was low for oysters in spat stage but increased with later life stages. Second, we confirmed a strong genetic basis of resistance to OsHV-1 infection at early stages and demonstrated that it was also strong at later stages. Most families had increased resistance to OsHV-1 infection from the spat to adult stages, while others consistently showed low or high mortality rates related to OsHV-1 infection, regardless of the life stage. Our third main finding was the absence of genetic correlations between resistance to OsHV-1 infection and resistance to V. aestuarianus infection.Conclusions: Selective breeding to enhance resistance to OsHV-1 infection could be achieved through selective breeding at early stages and would not affect resistance to V. aestuarianus infection. However, our results suggest that the potential to select for improved resistance to V. aestuarianus is lower. Selection for dual resistance to OsHV-1 and V. aestuarianus infection in C. gigas might reduce the impact of these two major diseases by selecting families that have the highest ... |
author2 |
Laboratoire de Génétique et Pathologie des Mollusques Marins (LGPMM) Unité Santé, Génétique et Microbiologie des Mollusques (SGMM) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR) Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM) Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) |
format |
Article in Journal/Newspaper |
author |
Azéma, Patrick Lamy, Jean-Baptiste Boudry, Pierre Renault, Tristan Travers, Marie-Agnès Dégremont, Lionel |
author_facet |
Azéma, Patrick Lamy, Jean-Baptiste Boudry, Pierre Renault, Tristan Travers, Marie-Agnès Dégremont, Lionel |
author_sort |
Azéma, Patrick |
title |
Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
title_short |
Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
title_full |
Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
title_fullStr |
Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
title_full_unstemmed |
Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages |
title_sort |
genetic parameters of resistance to vibrio aestuarianus, and oshv-1 infections in the pacific oyster, crassostrea gigas, at three different life stages |
publisher |
HAL CCSD |
publishDate |
2017 |
url |
https://hal.science/hal-01479152 https://hal.science/hal-01479152/document https://hal.science/hal-01479152/file/12711_2017_Article_297.pdf https://doi.org/10.1186/s12711-017-0297-2 |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
ISSN: 0999-193X EISSN: 1297-9686 Genetics Selection Evolution https://hal.science/hal-01479152 Genetics Selection Evolution, 2017, 49, pp.23. ⟨10.1186/s12711-017-0297-2⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12711-017-0297-2 hal-01479152 https://hal.science/hal-01479152 https://hal.science/hal-01479152/document https://hal.science/hal-01479152/file/12711_2017_Article_297.pdf doi:10.1186/s12711-017-0297-2 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1186/s12711-017-0297-2 |
container_title |
Genetics Selection Evolution |
container_volume |
49 |
container_issue |
1 |
_version_ |
1796941146116587520 |
spelling |
ftinsu:oai:HAL:hal-01479152v1 2024-04-21T08:00:43+00:00 Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages Azéma, Patrick Lamy, Jean-Baptiste Boudry, Pierre Renault, Tristan Travers, Marie-Agnès Dégremont, Lionel Laboratoire de Génétique et Pathologie des Mollusques Marins (LGPMM) Unité Santé, Génétique et Microbiologie des Mollusques (SGMM) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR) Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM) Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER) 2017-02-15 https://hal.science/hal-01479152 https://hal.science/hal-01479152/document https://hal.science/hal-01479152/file/12711_2017_Article_297.pdf https://doi.org/10.1186/s12711-017-0297-2 en eng HAL CCSD BioMed Central info:eu-repo/semantics/altIdentifier/doi/10.1186/s12711-017-0297-2 hal-01479152 https://hal.science/hal-01479152 https://hal.science/hal-01479152/document https://hal.science/hal-01479152/file/12711_2017_Article_297.pdf doi:10.1186/s12711-017-0297-2 info:eu-repo/semantics/OpenAccess ISSN: 0999-193X EISSN: 1297-9686 Genetics Selection Evolution https://hal.science/hal-01479152 Genetics Selection Evolution, 2017, 49, pp.23. ⟨10.1186/s12711-017-0297-2⟩ SELECTION ACL OSTREID HERPESVIRUS-1 INFECTION DISEASE RESISTANCE SUMMER MORTALITY HORIZONTAL TRANSMISSION PORTUGUESE OYSTER HERPES-VIRUS RISK-FACTORS FRANCE SPAT [SDV]Life Sciences [q-bio] [SDE.BE]Environmental Sciences/Biodiversity and Ecology info:eu-repo/semantics/article Journal articles 2017 ftinsu https://doi.org/10.1186/s12711-017-0297-2 2024-04-05T00:47:53Z International audience Background: In France, two main diseases threaten Pacific oyster production. Since 2008, Crassostrea gigas spat have suffered massive losses due to the ostreid herpesvirus OsHV-1, and since 2012, significant mortalities in commercial-size adults have been related to infection by the bacterium Vibrio aestuarianus. The genetic basis for resistance to V. aestuarianus and OsHV-1 and the nature of the genetic correlation between these two traits were investigated by using 20 half-sib sire families, each containing two full-sib families. For each disease, controlled infectious challenges were conducted using naïve oysters that were 3 to 26 months old. In addition, siblings were tested under field, pond and raceway conditions to determine whether laboratory trials reflected mortality events that occur in the oyster industry.Results: First, we estimated the genetic basis of resistance to V. aestuarianus in C. gigas. Susceptibility to the infection was low for oysters in spat stage but increased with later life stages. Second, we confirmed a strong genetic basis of resistance to OsHV-1 infection at early stages and demonstrated that it was also strong at later stages. Most families had increased resistance to OsHV-1 infection from the spat to adult stages, while others consistently showed low or high mortality rates related to OsHV-1 infection, regardless of the life stage. Our third main finding was the absence of genetic correlations between resistance to OsHV-1 infection and resistance to V. aestuarianus infection.Conclusions: Selective breeding to enhance resistance to OsHV-1 infection could be achieved through selective breeding at early stages and would not affect resistance to V. aestuarianus infection. However, our results suggest that the potential to select for improved resistance to V. aestuarianus is lower. Selection for dual resistance to OsHV-1 and V. aestuarianus infection in C. gigas might reduce the impact of these two major diseases by selecting families that have the highest ... Article in Journal/Newspaper Crassostrea gigas Pacific oyster Institut national des sciences de l'Univers: HAL-INSU Genetics Selection Evolution 49 1 |