Mutations in the stereospecificity pocket and at the entrance of the active site of Candida antarctica lipase B enhancing enzyme enantioselectivity
International audience Two different parts of Candida antarctica lipase B (stereospecificity pocket at the bottom of the active site and hydrophobic tunnel leading to the active site) were redesigned by single- or double-point mutations, in order to better control and improve enzyme enantioselectivi...
Main Authors: | , , , , , , , |
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Other Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2010
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Subjects: | |
Online Access: | https://hal.science/hal-00647795 https://hal.science/hal-00647795/document https://hal.science/hal-00647795/file/MOLCAB-D-09-00286_corrected.pdf |